Results 21 to 30 of about 226 (125)

Systematic Optimization of an SLE‐DAPTAD LC–MS/MS Workflow for Simultaneous Quantification of Low‐Abundance Vitamin D3 Metabolites in Plasma

Rapid Communications in Mass Spectrometry, Volume 40, Issue 20, 30 October 2026.
ABSTRACT Rationale Liquid chromatography–tandem mass spectrometry (LC–MS/MS) analysis of vitamin D3 metabolites is analytically challenging because these compounds are structurally similar, strongly matrix‐associated, and have poor ionization efficiency.
Marzieh Amirmostofian, Michael D. Wiese, Paul H. Anderson, Peter Hoffmann   +3 more
wiley   +1 more source

HvarAKR1B1‐mediated tolerance in Hippodamia variegata: Deciphering the metabolic adaptation and fitness costs under prolonged starvation

Pest Management Science, Volume 82, Issue 8, Page 7903-7914, August 2026.
Starvation stress significantly affected the growth and development of Hippodamia variegata. Combined transcriptome and metabolome analysis and RNA interference verification revealed that HvarAKR1B1 may be involved in the response of Hippodamia variegata to starvation stress.
Bing‐mei Song, De‐qin Hu, Yuan Li, Wang‐quan Jiao, Xiao‐li Ma, Hong‐sheng Pan   +5 more
wiley   +1 more source

Does the Combination of Abdominal Obesity and Vitamin D Deficiency Increase the Risk of Death in Individuals Aged 50 or Older? Evidence From the ELSA Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6607-6617, August 2026.
ABSTRACT Aims Despite the known association between abdominal obesity (AO) and vitamin D deficiency, it remains unclear whether this combination is associated with higher mortality risk. We investigated whether the coexistence of AO and vitamin D deficiency elevates the risk of death.
Joyce da Silva Milliati, Thaís Barros Pereira da Silva, Roberta de Oliveira Máximo, Mariane Marques Luiz, Sara Souza Lima, Andrew Steptoe, Cesar de Oliveira, Tiago da Silva Alexandre   +7 more
wiley   +1 more source

Metabolic engineering of Saccharomyces cerevisiae for 7-dehydrocholesterol overproduction [PDF]

Biotechnology for Biofuels, 2018
7-Dehydrocholesterol (7-DHC) has attracted increasing attentions due to its great medical value and the enlarging market demand of its ultraviolet-catalyzed product vitamin D3. Microbial production of 7-DHC from simple carbon has been recognized as an attractive complement to the traditional sources.
Xiao-Jing Guo, Wen-Hai Xiao, Ying Wang, Ming-Dong Yao, Bo-Xuan Zeng, Hong Liu, Guang-Rong Zhao, Ying-Jin Yuan   +7 more
openaire   +3 more sources

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, Volume 293, Issue 15, Page 4554-4577, August 2026.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Reconfiguring biofortification strategies to transform food systems and address micronutrient deficiency of the 21st century

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2511-2547, August 2026.
This review explores how to make staple foods and horticultural crops more nutritious, including how artificial intelligence‐based screening of gene banks helps deploy nutritionally rich germplasm into breeding. Genome editing can help develop crops richer in minerals, vitamins, and health‐promoting compounds, supporting healthier diets and more ...
Rhowell Jr. N. Tiozon, Alisdair R. Fernie, Nese Sreenivasulu   +2 more
wiley   +1 more source

Alliin Regulates Intracellular Cholesterol Metabolism Through the PCSK9/LDLR Axis in Ox‐LDL‐Induced HepG2 Cells: A Proteomics Study

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This study demonstrates that alliin reduces intracellular lipid accumulation and alters protein expression in ox‐LDL‐induced HepG2 cells. These effects are linked to cholesterol metabolism and the PPAR and PI3K/Akt signaling pathways. Mechanistically, alliin regulates the PCSK9/LDLR axis, indicating its role in maintaining intracellular cholesterol ...
Yuanyuan Tang, Xiaoshi Liu
wiley   +1 more source

The Photochemical Dehydrogenation of Ergosterol and 7-Dehydrocholesterol [PDF]

Bulletin of the Chemical Society of Japan, 1939
Abstract Ergopinacone and 7-dehydrocholesterol-pinacone have been prepared by two different methods, viz., the boiling method and the carbon dioxide method. The products obtained by the two methods as well as diacetates and dibenzoates derived from them have been compared.
openaire   +1 more source

Human Milk Bioactive Compounds and Psychomotor Outcomes in Infants and Children: A Systematic Review

Molecular Nutrition &Food Research, Volume 70, Issue 14, 29 July 2026.
In our review, we assess the role of HM fatty acids, oligosaccharides, proteins, and carotenoids, on psychomotor development in children up to 18 years. Findings suggest that HM BCs, particularly n‐3 PUFAs and fucosylated HMOs, might contribute to a favorable psychomotor development in infancy, preschool age, and school age.
Lara Huber, Eduard Flores Ventura, Regina Ensenauer, Daria Guseva   +3 more
wiley   +1 more source

Ontogenetic Sequence of Differential Gene Expression in Predator‐Induced Daphnia pulex

Molecular Ecology, Volume 35, Issue 13, July 2026.
ABSTRACT In response to predators, many Daphnia species develop inducible morphological defenses. These traits are phenotypically plastic, meaning their production is suppressed in the absence of the predator. While previous studies have identified several neurohumoral factors and candidate genes involved in the development of the defenses, the ...
Andrey Rozenberg, Linda C. Weiss, Tatjana Schwarz, Nancy Kühne, Uwe John, Ralph Tollrian   +5 more
wiley   +1 more source