Mechanisms of antiviral action and toxicities of ipecac alkaloids: Emetine and dehydroemetine exhibit anti-coronaviral activities at non-cardiotoxic concentrations [PDF]
Virus ResearchThe emergence of highly infectious pathogens with their potential for triggering global pandemics necessitate the development of effective treatment strategies, including broad-spectrum antiviral therapies to safeguard human health.
Arthur P. Grollman +2 more
exaly +4 more sources
Emetine, Ipecac, Ipecac Alkaloids and Analogues as Potential Antiviral Agents for Coronaviruses [PDF]
Pharmaceuticals, 2020 The COVID-19 coronavirus is currently spreading around the globe with limited treatment options available. This article presents the rationale for potentially using old drugs (emetine, other ipecac alkaloids or analogues) that have been used to treat ...
Martin D. Bleasel, Gregory M. Peterson
doaj +2 more sources
Emetine Is Not Ipecac: Considerations for Its Use as Treatment for SARS-CoV2 [PDF]
Pharmaceuticals, 2020 Emetine is a potent antiviral that acts on many viruses in the low-nM range, with several studies in animals and humans demonstrating antiviral activity.
Martin D. Bleasel, Gregory M. Peterson
doaj +2 more sources
Lead Optimization of Dehydroemetine for Repositioned Use in Malaria. [PDF]
Antimicrobial Agents and Chemotherapy, 2020 Niroshini J Nirmalan +2 more
exaly +2 more sources
Journal of Food Quality, Volume 2022, Issue 1, 2022., 2022 The Papaver L. plant (Papaver decaisnei) has ethnobotanical records in many countries including Iraqi Kurdistan. The current study investigates the methanol (99.9%) extracts (10 μg/mL) of roots, leaves, and flowers of Papaver decaisnei in terms of phytochemistry by gas chromatography‐mass spectrophotometry GC‐MS, in vitro antioxidant activity by ...
Ahmed Aj. Jabbar +5 more
wiley +1 more source
Hepatic amebiasis: experience in the therapy of 56 cases.
Acta Médica Portuguesa, 1981 The results of therapy in 56 consecutive cases of hepatic amebiasis are reviewed. In retrospect, the results in patients receiving metronidazole alone, dehydroemetine combined with chloroquine, and dehydroemetine combined with chloroquine and ...
Ireneu Cruz, F. J. Z. Carneiro Chaves
doaj +1 more source
Praziquantel Failure in the Treatment of Fasciola hepatica
Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 3, Issue 1, Page 33-36, 1992., 1990 A case of human fascioliasis is presented in which the patient remained symptomatic after treatment with praziquantel and other agents but eventually responded to bithionol. The difficulties in finding an efficacious and tolerable drug therapy for this condition are reviewed with reference to the life cycle and pathogenesis of the parasite.
David Michael Patrick +1 more
wiley +1 more source
The First Case of Human Hepatic Fasciolosis Presented as Hepatic Pseudotumor Histopathologically Diagnosed in Romania-A Case Report. [PDF]
Healthcare (Basel), 2023 Birlutiu V, Birlutiu RM.
europepmc +1 more source
Fasciola hepatica association with gallbladder malignancy: A rare case report. [PDF]
Trop Parasitol, 2021 Swain B, Otta S, Sahu MK, Uthansingh K.
europepmc +1 more source
Use of PCR in the diagnosis of pericardial amebiasis: a case report and systematic review of the literature. [PDF]
BMC Infect Dis, 2021 Matsuo T +13 more
europepmc +1 more source