Results 51 to 60 of about 13,186 (178)

Dehydroepiandrosterone and Its Metabolite 5-Androstenediol: New Therapeutic Targets and Possibilities for Clinical Application

Pharmaceuticals
Dehydroepiandrosterone and its sulfate are the most abundant steroids in humans. The metabolism of dehydroepiandrosterone can differ significantly depending on the organ or tissue and the subtype of steroid receptors expressed in it.
Tatiana A. Fedotcheva, Maria E. Uspenskaya, Darya N. Ulchenko, Nikolay L. Shimanovsky   +3 more
doaj   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Cellular and molecular mechanisms of action of neurosteroids in various parts of the central nervous system (Part 2)

Якутский медицинский журнал
Neurosteroids (or neuroactive steroids) are a class of endogenous compounds which are synthesized in nervous tissue or\and able to modulate the brain functional activity, the class also includes steroids from gonads or adrenals, which are capable of ...
D. V. Dmitrenko, S. N. Zobova, T. G. Ruksha, T. I. Prusova, A. A. Usoltseva   +4 more
doaj   +1 more source

Sex steroid hormones and allergic diseases in children: a pilot birth cohort study in the Japan Environment and Children’s Study cohort

BMC Pediatrics, 2023
Background Numerous studies suggest that sex steroids might play a role in sex disparity observed in allergic diseases in adults. However, whether sex hormones influence allergic diseases in children remains unclear.
Yumiko Miyaji, Kiwako Yamamoto-Hanada, Limin Yang, Mayako Saito-Abe, Miori Sato, Hidetoshi Mezawa, Minaho Nishizato, Masayuki Ochiai, Shouichi Ohga, Masako Oda, Hiroshi Mitsubuchi, Masayuki Shimono, Reiko Suga, Nathan Mise, Makiko Sekiyama, Shoji F. Nakayama, Yukihiro Ohya, the Japan Environment and Children’s Study (JECS)   +17 more
doaj   +1 more source

Anti‐Müllerian Hormone and Metabolic–Hormonal Profiles in Women With and Without Polycystic Ovary Syndrome: A Population‐Based Study

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
In this population‐based study of 883 women, AMH declined less with age in women with PCOS than in healthy women. Higher AMH may protect older healthy women from T2DM but indicates elevated metabolic risk in younger women with PCOS, supporting its role as a life‐course biomarker for metabolic risk stratification.
Fahimeh Ramezani Tehrani, Maryam Mousavi, Marzieh Saei Ghare Naz, Maryam Farahmand, Masoumeh Jorjani, Fatemeh Mahboobifard   +5 more
wiley   +1 more source

Oncocytoma Arising From an Accessory Adrenal Gland: A Case Report

IJU Case Reports, Volume 9, Issue 5, September 2026.
ABSTRACT Introduction Accessory adrenal oncocytomas are rare. Consequently, the clinical characteristics and management of this entity remain poorly defined. Case Presentation A 65‐year‐old man presented with a retroperitoneal mass. Imaging revealed a 103 × 96 mm tumor adjacent to the left kidney.
Yuki Seki, Kento Morozumi, Naomi Sato, Masaaki Oikawa, Hiroki Kusumoto, Nao Iwamoto, Naoki Kawamorita, Takayuki Yamada, Yasuhiro Nakamura, Yasuhiro Kaiho   +9 more
wiley   +1 more source

Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management

Clinical Endocrinology, Volume 105, Issue 3, Page 271-284, September 2026.
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu, Yue Li, Meng Sun, Yulin Li, Panpan Li, Hui Zou   +5 more
wiley   +1 more source

Maternal serum Dehydroepiandrosterone Sulfate levels and the efficiency of labor [PDF]

Acta Medica Iranica, 2001
To evaluate the maternal serum dehydroepiandrosterone (DHEA) sulfate levels as a factor influencing labor ‘efficiency’ at term and unsuccessful labor induction. This is a prospective study.
"Modares Gilani M, Peikari N, Ziai S, Faghihzadeh B "   +3 more
doaj   +2 more sources

Migraine and cluster headache show impaired neurosteroids patterns

The Journal of Headache and Pain, 2019
Background Perturbation of neuronal excitability contributes to migraine. Neurosteroids modulate the activity of γ-aminobutyric acid A and N-methyl-d-aspartate receptors, and might be involved in the pathogenesis of migraine.
Angela Koverech, Claudia Cicione, Luana Lionetto, Marta Maestri, Francesco Passariello, Elisabetta Sabbatini, Matilde Capi, Cristiano Maria De Marco, Martina Guglielmetti, Andrea Negro, Luisa Di Menna, Maurizio Simmaco, Ferdinando Nicoletti, Paolo Martelletti   +13 more
doaj   +1 more source

Circulating Sex Hormone Levels and Survival in Men With Esophageal Squamous Cell Carcinoma

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Men with esophageal squamous cell carcinoma (ESCC) have worse survival than women, a disparity in which sex hormones may play a role. Yet, whether circulating sex hormone levels are associated with survival in ESCC remains largely unexplored.
Zhiqiang Liu, Zhifeng Lin, Jesper Lagergren, Hejie Wang, Xiaodan Mao, Mei Ma, Zhijian Hu, Shao‐Hua Xie   +7 more
wiley   +1 more source