Results 151 to 160 of about 1,025,936 (342)

Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery

Advanced Healthcare Materials, EarlyView.
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang, Yue Hui, Zichao Guo, Dawei Liu, Yun Liu, Huajian Gao, Chun‐Xia Zhao   +6 more
wiley   +1 more source

Functionalized Reduced Graphene Oxide‐Based Nanocomposite Hydrogels for Enhanced Osteogenesis in Bone Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Charge‐opposed reduced graphene oxide fillers are co‐integrated into biopolymeric nanocomposite scaffolds, synergistically enhance osteogenesis. Multiscale characterization reveals how surface chemistry and porosity dictate ectopic mineral architecture.
George Mihail Vlăsceanu, Cătălina Ionela Zamfir, Cornel Baltă, Hildegard Herman, Alina Ciceu, Maria Alexandra Duma, Mariana Ioniță, Roxana‐Cristina Popescu, Anca Hermenean   +8 more
wiley   +1 more source

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

Proceedings of the National Academy of Sciences of the United States of America, 2010
A. Le, Charles R Cooper, A. Gouw, Ramani Dinavahi, A. Maitra, L. Deck, R. Royer, D. V. Vander Jagt, G. Semenza, C. Dang   +9 more
semanticscholar   +1 more source

Separation and Purification of Sarcosine Dehydrogenase and Dimethylglycine Dehydrogenase

Journal of Biological Chemistry, 1962
Wilhelm R. Frisell, Cosmo G. Mackenzie
openaire   +3 more sources

Inhalability and Bioactivity of Spray‐Dried versus Pressurized Gas eXpanded Liquid Technology‐Processed Yeast Beta‐Glucan Microparticles for Anti‐Fibrotic Therapies

Advanced Healthcare Materials, EarlyView.
PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall, Safaa Naiel, Quan Zhou, Pareesa Ali, Tamana Rubina Yousof, Emily Wong, Ricardo Couto, Byron Yépez, Bernhard Seifried, Paul Moquin, Rod Rhem, Myrna Dolovich, Martin Rainer Kolb, Kjetil Ask, Todd Hoare   +14 more
wiley   +1 more source

Biocompatible Multifunctional Polymeric Material for Mineralized Tissue Adhesion

Advanced Healthcare Materials, EarlyView.
A multifunctional thiol‐ene resin system is developed that provides a strong adhesive interface with dentin while maintaining biocompatibility with dental pulp cells. The addition of an acidic monomer to a triacrylate‐trithiol‐based resin achieves over 10 MPa shear bond strength by reinforcing the hybrid interface.
Yan Luo, Chenyang Zhang, Sage Fulco, Jingyi Liu, Keyu Chen, Yuntao Hu, Yuchen Jiang, Rui Xu, Leela Rakesh, Ozer Fusun, Ottman Tertuliano, Kevin Turner, Kyle H. Vining   +12 more
wiley   +1 more source

Regeneration of cofactor NAD(P)⁺ with NAD(P)H oxidase for the production of value-added chemicals. [PDF]

Front Bioeng Biotechnol
Zhou LJ, Long SX, Huan T, Wu Y, Zhang YW.   +4 more
europepmc   +1 more source

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

Advanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček   +8 more
wiley   +1 more source

Dysregulation of cellular metabolism within the gut-brain axis is associated with behavioural changes in chronic intestinal inflammation. [PDF]

J Neuroinflammation
Devereaux J, Robinson AM, Stavely R, Davidson M, Filippone RT, Ephraim R, Kiatos D, Apostolopoulos V, Nurgali K.   +8 more
europepmc   +1 more source

QUANTITATIVE ASSAY OF THE 3β-OL-DEHYDROGENASE SYSTEM IN WHOLE ADRENAL HOMOGENATE¹

, 1957
Benjamin Rubin, Ralph I. Dorfman
openalex   +1 more source