Results 11 to 20 of about 1,145,903 (339)

D-3-Phosphoglycerate Dehydrogenase [PDF]

Frontiers in Molecular Biosciences, 2018
l-Serine is the immediate precursor of d-serine, a major agonist of the N-methyl-d-aspartate (NMDA) receptor. l-Serine is a pivotal amino acid since it serves as a precursor to a large number of essential metabolites besides d-serine.
Gregory A. Grant, Gregory A. Grant
doaj   +3 more sources

Localization of TCA cycle dehydrogenases in the mitochondria [PDF]

, 1967
The site of localization of TCA cycle dehydrogenases in mitochondria has been investigated by observing the dehydrogenase activities and fine structure of the fractionated samples after freezing and thawing or sonication of beef heart and rat liver ...
Inaba, Kozo, Oda, Takuzo, Wakabayashi, Akira   +2 more
core   +1 more source

Advances in Immune Microenvironment and Immunotherapy of Isocitrate Dehydrogenase Mutated Glioma

Frontiers in Immunology, 2022
The tumor immune microenvironment and immunotherapy have become current important tumor research concerns. The unique immune microenvironment plays a crucial role in the malignant progression of isocitrate dehydrogenase (IDH) mutant gliomas.
Dongming Yan, Weicheng Li, Qibing Liu, Qibing Liu, Kun Yang   +4 more
doaj   +1 more source

New biotechnological perspectives of a NADH oxidase variant from Thermus thermophilus HB27 as NAD⁺-recycling enzyme

BMC Biotechnology, 2011
Background The number of biotransformations that use nicotinamide recycling systems is exponentially growing. For this reason one of the current challenges in biocatalysis is to develop and optimize more simple and efficient cofactor recycling systems ...
Rocha-Martín Javier, Vega Daniel, Bolivar Juan M, Godoy Cesar A, Hidalgo Aurelio, Berenguer José, Guisán José M, López-Gallego Fernando   +7 more
doaj   +1 more source

Alcohol dehydrogenase and aldehyde dehydrogenase in malignant neoplasms [PDF]

Clinical and Experimental Medicine, 2016
According to International Agency for Research on Cancer, ethanol and acetaldehyde belong to group 1 of human carcinogens. The accurate mechanism by which alcohol consumption enhances carcinogenesis is still unexplained. Alcohol is oxidized primarily by alcohol dehydrogenase (ADH) to acetaldehyde, a substance capable of initiating carcinogenesis by ...
Maciej Szmitkowski, Karolina Orywal
openaire   +3 more sources

Respiratory electron transfer pathways in plant mitochondria

Frontiers in Plant Science, 2014
The respiratory electron transport chain (ETC) couples electron transfer from organic substrates onto molecular oxygen with proton translocation across the inner mitochondrial membrane.
Peter eSchertl, Hans-Peter eBraun
doaj   +1 more source

Effect of Thiosemicarbazone Derivatives and Fusarium culmorum (Wm.G. Sm.) Sacc. Infection of Winter Wheat Seedlings on Their Health Status and Soil Biological Activity

Agronomy, 2022
Climate change has an impact on agricultural production, including the greater persistence of plant pathogens in the environment. Therefore, the question arises as to how to effectively and safely protect plants by using chemicals, the number of which is
Agnieszka Jamiołkowska, Barbara Skwaryło-Bednarz, Elżbieta Mielniczuk, Franco Bisceglie, Giorgio Pelosi, Francesca Degola, Anna Gałązka, Emilia Grzęda   +7 more
doaj   +1 more source

Functional Characterization and Structural Analysis of NADH Oxidase Mutants from Thermus thermophilus HB27: Role of Residues 166, 174, and 194 in the Catalytic Properties and Thermostability

Microorganisms, 2019
The Thermus thermophilus strain HB27 NADH-oxidase (Tt27-NOX) catalyzes the oxidation of nicotinamide adenine dinucleotide (NAD(P)H) by reducing molecular oxygen to hydrogen peroxide in a two-electron transfer mechanism.
Javier Rocha-Martin, Pedro A. Sánchez-Murcia, Fernando López-Gallego, Aurelio Hidalgo, José Berenguer, José M. Guisan   +5 more
doaj   +1 more source

Functional and Biogenetical Heterogeneity of the Inner Membrane of Rat-Liver Mitochondria [PDF]

, 1971
Rat liver mitochondria were fragmented by a combined technique of swelling, shrinking, and sonication. Fragments of inner membrane were separated by density gradient centrifugation.
Allmann D. W., Ashwell M., Beattie D. S., Beattie D. S., Brunner G., Burstone M. S., Davis K. A., Delbruck A., Fiske C. H., Folch J., Gear A. R. L., Gear A. R. L., Gear A. R. L., Gelder B. F., Gotterer G. S., Hasegawa E., Hawley E. S., Johnson A. B., Klingenberg M., Kuntzel H., Labbe R. F., Lentz P. E., Neupert W., Neupert W., Novikoff A. B., Ohnishi K., Omura T., Parsons D. F., Parsons D. F., Pette D., Pollak J. K., Pullmann M. E., Raw J., Raw J., Reith A., Schneider W. C., Schuel H., Schumacher H.-H., Sebald W., Sebald W., Seligman A. M., Sies H., Sottocasa G. L., Stoffel W., Strecker H. J., Swick R. W., Szarkowska L., Tabor C. W., Tol A., Vazquez J. J., Yonetani T.   +50 more
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Study of Surrogate Immunohistochemical Markers IDH1, ATRX, BRAF V600E, and p53 Mutation in Astrocytic and Oligodendroglial Tumors

Indian Journal of Neurosurgery, 2023
Introduction In consonance with current the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (2016), histological diagnosis of gliomas should be reinforced by molecular information.
Santosh Sharma, Kusum Mathur, Alka Mittal, Meel Mukta, Arpita Jindal, Mukesh Kumar   +5 more
doaj   +1 more source