Results 251 to 260 of about 543,196 (314)
Diallyl trisulfides (DATs) selectively induce cuproptosis in hepatic stellate cells (HSCs) by targeting Ras‐related protein Rab‐18 (RAB18) and regulating lipophagy. DATs promote RAB18 phase separation, enhance mitochondrial‐associated membrane structures (MAMs) formation, and increase succinylation of dihydrolipoamide dehydrogenase (DLD) at K320.
Haoyuan Tian+16 more
wiley +1 more source
Confined Migration Drives Stem Cell Differentiation
Human mesenchymal stem cell (hMSC) homing to sites of regeneration requires navigation through mechanically confining extracellular matrix environments, inducing rapid and dramatic morphological adaptation. By exposing hMSCs to specific levels of physiological confinement, it is demonstrated that confinement can induce osteogenesis, and that this fate ...
Xu Gao+6 more
wiley +1 more source
The Hydrolytic Activity of Glyceraldehyde-3-Phosphate Dehydrogenase
Jane Harting Park, Daniel E. Koshland
openalex +1 more source
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang+12 more
wiley +1 more source
Dehydrogenase Characteristics of the Pneumococci [PDF]
openaire +4 more sources
Genomic and Cis‐Regulatory Basis of a Plastic C3‐C4 Photosynthesis in Eleocharis Baldwinii
The sedge Eleocharis baldwinii remarkably switches between C3‐like and C4‐like photosynthesis in response to environmental conditions. Combining gap‐free genome assembly with single‐cell multi‐omics, this study uncovers how subgenome dominance and cell‐specific cis‐regulation enable C4 photosynthesis.
Lu Chen+11 more
wiley +1 more source
IR783‐stabilized nanodrugs composed of NIR dye IR783, ROS inducer β‐lapachone, and epigenetic modulator CUDC101 are designed for breast cancer immunotherapy. The nanodrugs can not only promote cancer cell apoptosis through HDAC inhibition‐enhanced oxidation therapy but also reshape the immunosuppressive microenvironment, which provides a novel strategy
Jinzhao Liu+6 more
wiley +1 more source
A FURTHER PURIFICATION OF d-GLUCOSE DEHYDROGENASE
Eleanor. Brunelli, W.W. Wainio
openalex +1 more source