Results 251 to 260 of about 1,210,240 (343)

Restoration of Enzymatic Activity of Energy-Related Proteins in Rats with Traumatic Brain Injury Following Administration of Gamma-Glutamylcysteine Ethyl Ester. [PDF]

Brain Sci
Rice B, Overbay J, Sebastian A, Sullivan PG, Reed TT.   +4 more
europepmc   +1 more source

Exploring Functionally Enhanced BLP‐Trained Macrophage Subpopulations in S. Aureus Infection: Underlying Mechanisms and Therapeutic Significance

Advanced Science, EarlyView.
BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan, Yinghao Hong, Xiangjun Ji, Jing Xiang, Jinxi Liu, Lixin Liang, Meng Ren, Wenhan Chen, Tengfei Xu, Zhijie Li, Tieliu Shi, Yong Jiang, Huaping Liang, Jinghua Liu   +13 more
wiley   +1 more source

Regeneration of cofactor NAD(P)⁺ with NAD(P)H oxidase for the production of value-added chemicals. [PDF]

Front Bioeng Biotechnol
Zhou LJ, Long SX, Huan T, Wu Y, Zhang YW.   +4 more
europepmc   +1 more source

Immp2l Enhances the Structure and Function of Mitochondrial Gpd2 Dehydrogenase [PDF]

Raymond A. Clarke, Hemna Govindaraju, Martina Beretta, Ellen M. Olzomer, Adam J. Lawther, Adam K. Walker, Zhiming Fang, Valsamma Eapen, Tzipi Cohen Hyams, Murray C. Killingsworth, Wallace Bridge, Nigel Turner, Khawar Sohail Siddiqui   +12 more
openalex   +1 more source

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids

Advanced Science, EarlyView.
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang, Tsering Yangzom, Ning Lu, Shenglong Deng, Xianglu Xiao, Guang Yang, Kristina Xiao Liang   +6 more
wiley   +1 more source

Clinical Significance of Lactate Dehydrogenase A Expression in Colorectal Cancer. [PDF]

Cureus
Ngamkham J, Moungthard H, Thesawadwomg T, Mus-U-Dee M, Phansri T, Boonmark K, Phukhan T.   +6 more
europepmc   +1 more source

Subventricular Zone‐on‐a‐Chip: A Model to Study Neurogenesis Disruption in Neonatal Intraventricular Hemorrhage

Advanced Science, EarlyView.
A human subventricular zone‐on‐a‐chip is developed to model intraventricular hemorrhage (IVH) in preterm infants. This platform enables the study of inflammation‐driven neurogenic disruption. Exposure to hemorrhagic cerebrospinal fluid and red blood cell lysate activated inflammatory pathways, with IL1B emerging as a key mediator.
Laura Nicoleti Zamproni, Begüm Gökçe, Magnus Gram, Coco Holliday, Aylin Sendemir, Marimélia Aparecida Porcionatto, Anna Herland   +6 more
wiley   +1 more source

Lactate Dehydrogenase-to-Albumin Ratio as a Predictor of In-Hospital Mortality in Predicted Severe Acute Pancreatitis: Evidence from an 18-Year Cohort Study. [PDF]

J Inflamm Res
Zou Y, Kuang M, Xiong S, Xu X, Li X, Ding L, He C, Li N, Ke H, Huang X, Lei Y, Xiong H, He W, Xia L, Lu N, Wan J, Zhu Y.   +16 more
europepmc   +1 more source

Dehydrogenase Characteristics of the Pneumococci [PDF]

Journal of Bacteriology, 1945
openaire   +3 more sources

Replacing BPA: Structural Substitutes BPAF Binding to the Progesterone Receptor Elevates Breast Cancer Risk

Advanced Science, EarlyView.
This study demonstrates that bisphenol analogues, particularly BPAF, bind to progesterone receptor, promoting breast cancer cell proliferation, migration, and mammary tumor growth, indicating that bisphenol A substitutes may pose equal or greater health risks.
Xiaotong Ji, Peilin Li, Haoyang Wu, Linzhuo Shen, Xiaoyun Wu, Peiyun Jiang, Yating Li, Xiaozheng Zhang, Huifeng Yue   +8 more
wiley   +1 more source