Results 261 to 270 of about 543,196 (314)
Enzyme response to thyrotoxicosis and hypothyroidism in human liver and muscle [PDF]
, 1972 Bachmaier, B. +5 more
core
Apoptotic Bodies Restore NAD and Mitochondrial Homeostasis in Fibroblasts
Advanced Science, EarlyView.Mesenchymal stem cell‐derived apoptotic bodies (MSC‐ABs) target keloid fibroblasts (KFs), restoring nicotinamide adenine dinucleotide (NAD) metabolism and mitochondrial function, suppressing collagen overproduction, and rebalancing tissue homeostasis, offering a novel therapy for keloid.
Shutong Qian +10 more
wiley +1 more source
Advanced Science, EarlyView.Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen +12 more
wiley +1 more source
Advanced Science, EarlyView.Enhanced arginine uptake is a critical feature of metabolic reprogramming in PTCL, characterized by elevated expression of the arginine transporter SLC3A2. SLC3A2‐mediated arginine uptake facilitates PTCL proliferation and survival by enhancing OXPHOS metabolism and inducing immune evasion.
Yimin Ren +13 more
wiley +1 more source
The Inhibition of Beef Liver Glutamic Dehydrogenase by Metal-binding Agents
, 1959 S. James Adelstein, Bert L. Vallée
openalex +1 more source
Structural and Biochemical Characterization of a Widespread Enterobacterial Peroxidase Encapsulin
Advanced Science, EarlyView.Encapsulins are self‐assembling bacterial protein compartments loaded with cargo enzymes. The most abundant encapsulin cargo class are Dye‐decolorizing Peroxidases (DyPs). In this study, we structurally and biochemically characterize a DyP encapsulin found in many enterobacteria.
Natalia C. Ubilla‐Rodriguez +2 more
wiley +1 more source
Advanced Science, EarlyView.Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang +10 more
wiley +1 more source
ON THE ACTION OF PYROPHOSPHATE ON 3-PHOSPHOGLYCERALDEHYDE DEHYDROGENASE
, 1957 Gale W. Rafter, Sidney P. Colowick
openalex +1 more source
Advanced Science, EarlyView.The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou +11 more
wiley +1 more source