Results 31 to 40 of about 1,320,603 (414)
Molecular mechanisms of the non-coenzyme action of thiamin in brain. Biochemical, structural and pathway analysis [PDF]
, 2015 Thiamin (vitamin B1) is a pharmacological agent boosting central metabolism through the action of the coenzyme thiamin diphosphate (ThDP). However, positive effects, including improved cognition, of high thiamin doses in neurodegeneration may be ...
Andrey, Vovk +9 more
core +1 more source
Journal of the National Cancer Institute, 2017 The mitochondrial pyruvate dehydrogenase complex (PDC) irreversibly decarboxylates pyruvate to acetyl coenzyme A, thereby linking glycolysis to the tricarboxylic acid cycle and defining a critical step in cellular bioenergetics.
P. Stacpoole
semanticscholar +1 more source
Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis
Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022 One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen +3 more
wiley +1 more source
Microbial Activity in Forest Soil Under Beech, Spruce, Douglas Fir and Fir
Contemporary Agriculture, 2016 The aim of this research was to investigate the microbial activity in forest soil from different sites under deciduous and coniferous trees in Serbia.
Hajnal-Jafari Timea +4 more
doaj +1 more source
Indian Journal of Neurosurgery, 2023 Introduction In consonance with current the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (2016), histological diagnosis of gliomas should be reinforced by molecular information.
Santosh Sharma +5 more
doaj +1 more source
Kinetic Model for a Threshold Filter in an Enzymatic System for Bioanalytical and Biocomputing Applications [PDF]
J. Phys. Chem. B 118, 12435-12443 (2014), 2014 A recently experimentally observed biochemical "threshold filtering" mechanism by processes catalyzed by the enzyme malate dehydrogenase is explained in terms of a model that incorporates an unusual mechanism of inhibition of this enzyme that has a reversible mechanism of action.
arxiv +1 more source
Identification of 3-deoxyglucosone dehydrogenase as aldehyde dehydrogenase 1A1 (retinaldehyde dehydrogenase 1) [PDF]
Biochimie, 2007 One of the metabolic fates of 3-deoxyglucosone, a product of protein deglycation and a potent glycating agent, is to be oxidized to 2-keto-3-deoxygluconate, but the enzyme that catalyzes this reaction is presently unknown. Starting from human erythrocytes, which are known to convert 3-deoxyglucosone to 2-keto-3-deoxygluconate, we have purified to near ...
Collard, François +4 more
openaire +4 more sources
Phenotypic continuum of NFU1‐related disorders
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 2025-2035, December 2022., 2022 Abstract Bi‐allelic variants in Iron–Sulfur Cluster Scaffold (NFU1) have previously been associated with multiple mitochondrial dysfunctions syndrome 1 (MMDS1) characterized by early‐onset rapidly fatal leukoencephalopathy. We report 19 affected individuals from 10 independent families with ultra‐rare bi‐allelic NFU1 missense variants associated with a
Rauan Kaiyrzhanov +45 more
wiley +1 more source
Assessment of the microbiological activity in agricultural and urban soils
Soil Science Annual, 2014 The aim of this study was to evaluate the enzymatic soil and the number of selected microorganisms in urban soil, which are located in the lane of the reconstructed road and compare it with a soil cultivated for agricultural purposes.
DEC DOROTA
doaj +1 more source
Agronomy, 2021 Soil pollution by trace elements is a huge problem around the globe. In addition, heavy metal immobilization and primary productivity are two soil ecosystem services of contemporary importance to society.
Paloma Campos +3 more
doaj +1 more source