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Formate is a substrate, or product, of diverse reactions catalyzed by eukaryotic organisms, eubacteria, and archaebacteria. A survey of metabolic groups reveals that formate is a common growth substrate, especially among the anaerobic eubacteria and archaebacteria.
openaire +2 more sources
Immunosuppressants and risk of Parkinson disease [PDF]
We performed a population-based case-control study of United States Medicare beneficiaries age 60-90 in 2009 with prescription data (48,295 incident Parkinson disease cases and 52,324 controls) to examine the risk of Parkinson disease in relation to use ...
Camacho-Soto, Alejandra+5 more
core +2 more sources
Introduction In consonance with current the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (2016), histological diagnosis of gliomas should be reinforced by molecular information.
Santosh Sharma+5 more
doaj +1 more source
Isocitrate dehydrogenase mutations in myeloid malignancies
Alterations to genes involved in cellular metabolism and epigenetic regulation are implicated in the pathogenesis of myeloid malignancies. Recurring mutations in isocitrate dehydrogenase (IDH) genes are detected in approximately 20% of adult patients ...
B. Medeiros+5 more
semanticscholar +1 more source
Study on metabolic status of tear fluid in hypothyroidism patients with dry eye syndrome
Introduction. Dry eye syndrome (DES) is associated with a complicated multifactorial mechanism, the peculiarities of which are being studied at the moment.
M.I. Pavlovskii , G.I. Drozhzhyna
doaj +1 more source
The paper presents data on a three-year study (2020-2022) of the effect of a liquid-phase biological product containing iron nanoparticles (LPB-Fe), obtained by biosynthesis using green tea extract, on the yield of potatoes of the Skarb variety and the ...
N. A. Lyubimova, G. Yu. Rabinovich
doaj +1 more source
Integrating Horizontal Gene Transfer and Common Descent to Depict Evolution and Contrast It with ‘‘Common Design [PDF]
Horizontal gene transfer (HGT) and common descent interact in space and time. Because events of HGT co-occur with phylogenetic evolution, it is difficult to depict evolutionary patterns graphically. Tree-like representations of life’s diversification are
Espinosa, Avelina+1 more
core +2 more sources
Mitochondrial dysfunction is a hallmark of metabolic diseases such as obesity, type 2 diabetes mellitus, neurodegenerative diseases, and cancers. Dysfunction occurs in part because of altered regulation of the mitochondrial pyruvate dehydrogenase complex
Sungmi Park+6 more
semanticscholar +1 more source
E2F1 Suppresses Oxidative Metabolism and Endothelial Differentiation of Bone Marrow Progenitor Cells [PDF]
RATIONALE: The majority of current cardiovascular cell therapy trials use bone marrow progenitor cells (BM PCs) and achieve only modest efficacy; the limited potential of these cells to differentiate into endothelial-lineage cells is one of the major ...
Boriboun, Chan+17 more
core +1 more source
Cancer cells use alterations of normal metabolic processes to sustain proliferation indefinitely. Transcriptional and posttranscriptional control of the pyruvate dehydrogenase kinase (PDK) family is one way in which cancer cells alter normal pyruvate ...
B. Woolbright+3 more
semanticscholar +1 more source