Results 81 to 90 of about 3,913,526 (305)

Bandwidth-Unlimited, Dispersion-Free Tunable Optical Delay Using a Prism Pair [PDF]

arXiv, 2009
We report a nearly perfect bandwidth-unlimited, dispersion-free tunable optical delay system using a prism pair. The observed delay-bandwidth product using a 25-femtosecond light pulse is ~7x104, where the delay time is independent of the signal bandwidth. The present technique breaks from the conventional methods constrained by delay-bandwidth product,
arxiv  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Ergodic Interference Alignment with Delayed Feedback [PDF]

arXiv, 2013
We propose new ergodic interference alignment techniques for $K$-user interference channels with delayed feedback. Two delayed feedback scenarios are considered -- delayed channel information at transmitter (CIT) and delayed output feedback. It is proved that the proposed techniques achieve total $2K/(K+2)$ DoF which is higher than that by the ...
arxiv  

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Numerical bifurcation and hybrid control of a Gompertz model with time delay

Journal of Hebei University of Science and Technology, 2019
In order to study the stability of species, the biological systems are required to reduce or expand the stable region. For a Gompertz model with time delay, a hybrid control Euler method is proposed in which state feedback and parameter perturbation are ...
Jizhi SONG, Yuanyuan WANG
doaj   +1 more source

On the Min-Max-Delay Problem: NP-completeness, Algorithm, and Integrality Gap

, 2018
We study a delay-sensitive information flow problem where a source streams information to a sink over a directed graph G(V,E) at a fixed rate R possibly using multiple paths to minimize the maximum end-to-end delay, denoted as the Min-Max-Delay problem ...
Chen, Minghua, Deng, Lei, Liu, Qingyu, Zeng, Haibo   +3 more
core   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

2,5-Dimethyl-4-hydroxy-3(2H)-furanone (Furaneol®) from Methyl ?-D-Glucopyranoside

CHIMIA, 1992
An efficient synthesis of 2,5-dimethyl-4-hydroxy-3(2H)-furanone (Furaneol®), an important strawberry flavour, starting from the readily available and cheap methyl ?-D-glucopyranoside is described.
François Mazenod, François Delay, Ferdinand Näf   +2 more
doaj   +2 more sources

Delay time modulation induced oscillating synchronization and intermittent anticipatory/lag and complete synchronizations in time-delay nonlinear dynamical systems [PDF]

arXiv, 2005
Existence of a new type of oscillating synchronization that oscillates between three different types of synchronizations (anticipatory, complete and lag synchronizations) is identified in unidirectionally coupled nonlinear time-delay systems having two different time-delays, that is feedback delay with a periodic delay time modulation and a constant ...
arxiv