Results 61 to 70 of about 43,728 (258)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Periodic Solutions in a Simple Delay Differential Equation

Mathematical and Computational Applications
A simple-form scalar differential equation with delay and nonlinear negative periodic feedback is considered. The existence of several types of slowly oscillating periodic solutions is shown with the same and double periods of the feedback coefficient ...
Anatoli Ivanov, Sergiy Shelyag
doaj   +1 more source

Stability of delay differential equations via delayed matrix sine and cosine of polynomial degrees

Advances in Difference Equations, 2017
In this paper, we study the finite time stability of delay differential equations via a delayed matrix cosine and sine of polynomial degrees. Firstly, we give two alternative formulas of the solutions for a delay linear differential equation.
Chengbin Liang, Wei Wei, JinRong Wang
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Dynamics of a state-dependent delay-differential equation

Electronic Journal of Qualitative Theory of Differential Equations
We present a detailed study of a scalar differential equation with threshold state-dependent delayed feedback. This equation arises as a simplification of a gene regulatory model.
Tomas Gedeon, Antony Humphries, Michael Mackey, Hans-Otto Walther, Zhao Wang   +4 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Asymptotic Stability of Differential Equations with Infinite Delay

Journal of Applied Mathematics, 2012
A theorem on asymptotic stability is obtained for a differential equation with an infinite delay in a function space which is suitable for the numerical computation of the solution to the infinite delay equation.
D. Piriadarshani, T. Sengadir
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

On the stability of the third order partial differential equation with time delay

Қарағанды университетінің хабаршысы. Математика сериясы
In this paper, the initial value problem for a third-order partial differential equation with time delay within a Hilbert space was analyzed. We establish a key theorem regarding the stability of this problem.
A. Ashyralyev, S. Ibrahim, E. Hincal
doaj   +1 more source

Oscillatory behavior of the second order noncanonical differential equations

Electronic Journal of Qualitative Theory of Differential Equations, 2019
Establishing monotonical properties of nonoscillatory solutions we introduce new oscillatory criteria for the second order noncanonical differential equation with delay/advanced argument \begin{equation*} (r(t)y'(t))'+p(t)y(\tau(t))=0. \end{equation*}
Blanka Baculíková
doaj   +1 more source