Results 101 to 110 of about 673,566 (301)

Impulsivity Relates To Striatal Gray Matter Volumes In Humans: Evidence From A Delay Discounting Paradigm

open access: yesFrontiers in Human Neuroscience, 2015
Time-stable personality traits, such as impulsivity and its relationship with functional and structural brain alterations, have gained much attention in the recent literature.
Melanie eTschernegg   +7 more
doaj   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló   +5 more
wiley   +1 more source

Gamification and motivation: Impact on delay discounting performance.

open access: yesPLoS ONE
Delay discounting is a phenomenon strongly associated with impulsivity. However, in order for a measured discounting rate in an experiment to meaningfully generalize to choices made elsewhere in life, participants must provide thoughtful, engaged answers
Sophie Harvey   +2 more
doaj   +1 more source

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

Event-Related Potentials Reveal Differential Brain Regions Implicated in Discounting in Two Tasks [PDF]

open access: yes
The way people make decisions about future benefits termed discounting - has important implications for both financial planning and health behaviour. Several theories assume that, when delaying gratification, the lower weight given to future benefits ...
Richard A.P. Roche   +4 more
core  

Anxious Individuals Are Impulsive Decision-Makers in the Delay Discounting Task: An ERP Study [PDF]

open access: yes, 2017
Impulsivity, which is linked to a wide range of psychiatric disorders, is often characterized by a preference for immediate but smaller rewards over delayed but larger rewards. However, debate exists on the relationship between anxiety and impulsivity.
Yuejia Luo   +7 more
core   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić   +4 more
wiley   +1 more source

Time Preference, Time Discounting, and Smoking Decisions [PDF]

open access: yes
This study examines the relationship between time discounting, other sources of time preference, and intertemporal choices about smoking. Using a survey fielded for our analysis, we elicit rates of time discount from choices in financial and health ...
Dan Silverman, Frank Sloan, Ahmed Khwaja
core  

Single‐subject designs in character education: Methods for rigorous, contextual, and practitioner‐led research

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Character education research is often constrained by blunt methodological tools. Surveys capture breadth without depth; case studies offer richness but lack replicability; and randomised controlled trials (RCTs), though indispensable at the policy level, are costly, disruptive and ill‐suited to everyday practice with individual pupils.
Shane McLoughlin
wiley   +1 more source

‘I was treated as a deficit’: Immigrant teachers' career progression in Australia

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Immigrant teachers have long been recruited through skilled and employer‐sponsored migration schemes to address teacher shortages in Australia, yet their career trajectories remain constrained by systemic inequities that limit their integration and professional development opportunities.
Ching Ting Tany Kwee   +2 more
wiley   +1 more source

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