Results 61 to 70 of about 573,656 (267)

SAW devices and its signal processing applications

open access: yesVojnotehnički Glasnik, 1999
SAW or surface acoustic wave devices have a wide application in analog signal processing. Many different signal processing functions can be achieved by different SAW devices.
Igor S. Simić , Aleksa J. Zejak
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Miniaturized overlapped LC phase delay line

open access: yesAIP Advances, 2014
A novel miniaturized ultra-wide bandwidth (DC–35 GHz) LC phase delay line (PDL) based on overlapped meander inductors and air-bridge capacitors is proposed and fabricated.
Xin Guo, Ling Li, Chenxu Zhao, Zewen Liu
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Single-Path High-Resolution Digital PWM Architectures With Cascadability of Delay Lines

open access: yesIEEE Open Journal of Power Electronics
This paper introduces two new single-path and cascaded High-Resolution Digital Pulse Width Modulation (HRDPWM) architectures. The proposed single-path architecture uses fewer FPGA resources to achieve the same resolution as conventional dual-path ...
Marziyeh Hajiheidari   +5 more
doaj   +1 more source

A Linearization Time-Domain CMOS Smart Temperature Sensor Using a Curvature Compensation Oscillator

open access: yesSensors, 2013
This paper presents an area-efficient time-domain CMOS smart temperature sensor using a curvature compensation oscillator for linearity enhancement with a −40 to 120 °C temperature range operability.
Hao-Wen Chen, Chun-Chi Chen
doaj   +1 more source

Linear rotary optical delay lines

open access: yesOptics Express, 2014
I present several classes of analytical and semi-analytical solutions for the design of high-speed rotary optical delay lines that use a combination of stationary and rotating curvilinear reflectors. Detailed analysis of four distinct classes of optical delay lines is presented. Particularly, I consider delay lines based on a single rotating reflector,
openaire   +3 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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