Results 71 to 80 of about 5,559,122 (287)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Miniaturized overlapped LC phase delay line

open access: yesAIP Advances, 2014
A novel miniaturized ultra-wide bandwidth (DC–35 GHz) LC phase delay line (PDL) based on overlapped meander inductors and air-bridge capacitors is proposed and fabricated.
Xin Guo, Ling Li, Chenxu Zhao, Zewen Liu
doaj   +1 more source

A Linearization Time-Domain CMOS Smart Temperature Sensor Using a Curvature Compensation Oscillator

open access: yesSensors, 2013
This paper presents an area-efficient time-domain CMOS smart temperature sensor using a curvature compensation oscillator for linearity enhancement with a −40 to 120 °C temperature range operability.
Hao-Wen Chen, Chun-Chi Chen
doaj   +1 more source

Continuously Tuneable MZI-based Delay Line Overcoming Delay-Bandwidth Product

open access: yes, 2022
A silicon photonic integrated circuit, implementing a novel delay-line architecture, is proposed. The device, based on a set of four nested Mach-Zehnder Interferometers, overcomes typical delay-bandwidth product.
Matteo Petrini   +3 more
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

A Kac CROW delay line

open access: yes2013 IEEE Photonics Conference, 2013
A low-loss CROW delay line with a weak inter-resonator coupling determined by the Kac matrix is dispersionless and can be easily impedance-matched by adjusting the coupling to the input/output waveguide.
openaire   +2 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

THEORY OF GUIDED WAVES IN THE INFINITE SYSTEMS OF COUPLED DIELECTRIC RESONATORS

open access: yesInformation and Telecommunication Sciences
Background. One of the promising elements of optical and quantum communication systems is various delay lines built on the high-quality dielectric resonators (DRs).
Alexander Trubin
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

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