Results 71 to 80 of about 573,656 (267)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Unified Interpretation of Angular and Cumulative Angular Phase Representations with Best-Practice Guidelines for Differential Phase Shift Extraction in Nematic Liquid Crystal-Based Reconfigurable Phase Shifters

Crystals
Electromagnetic phase reconfigurability is a critical functionality for many emerging applications in electronics, defence, and other disruptive technologies.
Jinfeng Li, Haorong Li, Yunchen Xiao
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Long-range frequency-domain optical delay line based on a spinning tilted mirror for low-cost ocular biometry. [PDF]

Biomed Opt Express, 2023
Urizar MP, Gambra E, de Castro A, de la Peña Á, Pascual D, Cetinkaya O, Marcos S, Curatolo A.   +7 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Development and research of the structure of a digital frequency meter for an instantaneous frequency measurement system

Омский научный вестник
The article proposes a new method for measuring frequency based on a one-bit ADC. In contrast to the known method of measuring frequency using a delay line, the developed structure of a meter that implements the proposed method makes it possible to get ...
A. N. Lyashuk, P. I. Puzyrev, S. A. Zavyalov   +2 more
doaj   +1 more source

Attosecond stable dispersion-free delay line for easy ultrafast metrology. [PDF]

Sci Rep, 2022
Tyagi A, Sidhu MS, Mandal A, Kapoor S, Dahiya S, Rost JM, Pfeifer T, Singh KP.   +7 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Preparation of MoS₂ Nanospheres using a Hydrothermal Method and Their Application as Ammonia Gas Sensors Based on Delay Line Surface Acoustic Wave Devices. [PDF]

Materials (Basel), 2023
Chung CY, Chen YC, Juang FR, Kao KS, Lee EI.   +4 more
europepmc   +1 more source