Results 81 to 90 of about 5,559,122 (287)

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Highly scalable serial-parallel optical delay line

open access: yes, 2003
We present a complete analysis of the operation of an ultra-fast tunable parallel optical delay line. Based on our analysis, we propose and experimentally demonstrate a generalized serial–parallel delay line structure, which provides better scalability ...
Glesk, Ivan   +4 more
core   +3 more sources

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Estimating Angle of Arrival (AOA) for Wideband Signal by Sensor Delay Line (SDL) and Tapped Delay Line (TDL) Processors

open access: yesJournal of Engineering, 2018
Angle of arrival (AOA) estimation for wideband signal becomes more necessary for modern communication systems like Global System for Mobile (GSM), satellite, military applications and spread spectrum (frequency hopping and direct sequence).
Bassim Sayed Mohammed   +1 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Acoustic sensor for remote measuring of pressure [PDF]

open access: yesTekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2008
The paper deals with sensors based on delay lines on surface acoustic waves (SAW), having a receiving-emitting and a reflective interdigital transducers (IDT).
Kataev V. F.   +3 more
doaj  

A p-HEMT 920 ps True Time Delay Line Integrated Circuit for X-Band Imaging Radars [PDF]

open access: yesJournal of Microwaves, Optoelectronics and Electromagnetic Applications
This paper presents a novel design of an X-band (812 GHz) 4-bit monolithic microwave integrated circuit (MMIC) type true-time-delay (TTD) line for wideband high-resolution imaging radar applications.
Kilari Sreenivasulu   +3 more
doaj   +1 more source

On Global Exponential Stability Preservation under Sampling for Globally Lipschitz Delay-Free and Retarded Systems

open access: yes, 2016
The paper shows that the global exponential stability property is preserved, under suitable fast sampling, whenever the dynamics of the system at hand is described by globally Lipschitz functions.
Fridman, E., PEPE, PIERDOMENICO
core   +1 more source

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