Pathophysiology of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage: A Review [PDF]
Delayed cerebral ischemia is a major predictor of poor outcomes in patients who suffer subarachnoid hemorrhage. Treatment options are limited and often ineffective despite many years of investigation and clinical trials.
William S. Dodd +9 more
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Beyond Vasospasm: Dual Milrinone and Balloon Angioplasty in Refractory Delayed Cerebral Ischemia Post‐Subarachnoid Hemorrhage [PDF]
Cerebral vasospasm is a major complication of aneurysmal subarachnoid hemorrhage and a key contributor to delayed cerebral ischemia, which remains a leading cause of morbidity despite standard therapy with nimodipine and induced hypertension.
Paul Cardozo Gil +7 more
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Time-to-maximum Analysis Using Rapid Processing of Perfusion and Diffusion Software for Assessment of the Risk of Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage [PDF]
Perfusion computed tomography predicts and diagnoses delayed cerebral ischemia after subarachnoid hemorrhage, but challenges in precision and interpretation limit its adoption.
Shimpei TSUBOKI +6 more
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Comparison of non-contrast CT, CT perfusion, and CT angiography for predicting delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage [PDF]
Objective Non-contrast CT (NCCT), CT perfusion (CTP), and CT angiography (CTA) are recommended for predicting delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH). However, not all patients can undergo all three examinations on
Xin Yao +7 more
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Delayed cerebral ischemia and therapeutic approaches after subarachnoid hemorrhage
Delayed cerebral ischemia after subarachnoid hemorrhage is one of the most important causes of mortality and poor functional outcome in patients. Initially, the etiology and treatment of delayed cerebral ischemia focused primarily on cerebral vasospasm ...
Fettah Eren +4 more
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Early MEK1/2 inhibition after global cerebral ischemia in rats reduces brain damage and improves outcome by preventing delayed vasoconstrictor receptor upregulation. [PDF]
BACKGROUND: Global cerebral ischemia following cardiac arrest is associated with increased cerebral vasoconstriction and decreased cerebral blood flow, contributing to delayed neuronal cell death and neurological detriments in affected patients.
Sara Ellinor Johansson +3 more
doaj +1 more source
Multimodality Monitoring for Delayed Cerebral Ischemia in Subarachnoid Hemorrhage: A Mini Review
Aneurysmal subarachnoid hemorrhage is a disease with high mortality and morbidity due in large part to delayed effects of the hemorrhage, including vasospasm, and delayed cerebral ischemia.
Collin M. Labak +7 more
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Plain Language Summary Aneurysmal subarachnoid hemorrhage is a medical emergency in which an aneurysm, a weakened outpouching of a cerebral blood vessel, ruptures causing bleeding in the subarachnoid space.
François-Xavier Chalet +5 more
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Background: Delayed cerebral ischemia is a common complication after aneurysmal subarachnoid hemorrhage, which accounts for high morbidity and mortality in these patients.
N.O.S. Moreno +3 more
doaj +1 more source
Cocaine is a known vasoactive drug associated with poor clinical outcomes and high in-hospital mortality related to aneurysmal subarachnoid hemorrhage; however, the association of prior cocaine use with the incidence of vasospasm and delayed cerebral ...
Brendan J. Klein, DO +5 more
doaj +1 more source

