Results 71 to 80 of about 154,529 (215)

The Intersection of Fracture Healing and Infection: ORS Workshop 2021

open access: yesJournal of Orthopaedic Research, 2022
Infection is a common cause of impaired fracture healing. In the clinical setting, definitive fracture treatment and infection are often treated separately and sequentially, by different clinical specialties.
Justin E. Hellwinkel   +5 more
semanticscholar   +1 more source

Impact of osteoporosis and osteoporosis medications on fracture healing: a narrative review

open access: yesOsteoporosis International
Antiresorptive medications do not negatively affect fracture healing in humans. Teriparatide may decrease time to fracture healing. Romosozumab has not shown a beneficial effect on human fracture healing.
M. Chandran   +39 more
semanticscholar   +1 more source

Which non-infection related risk factors are associated with impaired proximal femur fracture healing in patients under the age of 70 years?

open access: yesBMC Musculoskeletal Disorders, 2023
Background/purpose Impaired healing is a feared complication with devastating outcomes for each patient. Most studies focus on geriatric fracture fixation and assess well known risk factors such as infections.
Sascha Halvachizadeh   +6 more
doaj   +1 more source

Temporal dynamics of immune-stromal cell interactions in fracture healing

open access: yesFrontiers in Immunology
Bone fracture repair is a complex, multi-step process that involves communication between immune and stromal cells to coordinate the repair and regeneration of damaged tissue. In the US, 10% of all bone fractures do not heal properly without intervention,
Christina A. Capobianco   +2 more
semanticscholar   +1 more source

Analysis of delayed fracture healing following unreamed tibial nailing

open access: yes, 2004
In order to determine the factors that affect tibial fracture union after unreamed nailing and the variables that have a negative impact on the healing process or the complication rate, 158 patients with 160 tibial shaft fractures treated using the AO ...
Salem, Khaled Hamed
core   +1 more source

Altering the course of fracture healing monitoring

open access: yes, 2023
Effective detection of delayed union and non-union related to bone fracture healing can reduce the individual and social burdens associated with fracture management.
Marco P. Soares dos Santos   +2 more
core   +1 more source

Fracture healing in the elderly: A review.

open access: yes, 2016
Older patients are commonly at a higher risk of experiencing a bone fracture. Complications during fracture healing, including delayed union and non-union, can arise as a result of a multitude of patient and treatment factors. This review describes those
Murray, David W.   +3 more
core   +1 more source

Insufficient Mechanical Loading Downregulates Piezo1 in Chondrocytes and Impairs Fracture Healing Through ApoE‐Induced Senescence

open access: yesAdvancement of science
Insufficient mechanical loading impairs fracture healing; however, the underlying mechanisms remain unclear. Increasing evidence indicates that Piezo1 plays an important role in fracture healing, although the effect of Piezo1 on the endochondral ...
Siming Jia   +13 more
semanticscholar   +1 more source

Influence of the mechanical environment upon the healing of segmental bone defects in the rat femur [PDF]

open access: yes
Loss of large segments of bone creates critical size defects (CSDs). These fail to heal spontaneously and present major clinical challenges to orthopaedic surgeons. The research described in this thesis is based upon the hypothesis that the healing of
Glatt, Vaida
core  

Functional mechanism and clinical implications of mir-1271-5p in pilon fracture healing processes

open access: yesJournal of Orthopaedic Surgery and Research
Pilon fractures are challenging to treat and carry a risk of delayed healing. MicroRNA (miRNA) is closely associated with various diseases due to its ability to regulate gene expression.
Zhihan Zhang   +4 more
semanticscholar   +1 more source

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