Results 61 to 70 of about 154,529 (215)

Simulation of the nutrient supply in fracture healing

open access: yes, 2009
The healing process for bone fractures is sensitive to mechanical stability and blood supply at the fracture site. Most currently available mechanobiological algorithms of bone healing are based solely on mechanical stimuli, while the explicit analysis ...
Schuetz, M.A.   +6 more
core   +1 more source

MiR-328-5p/BCL7A axis is involved in fracture healing by modulating osteoblast function

open access: yesJournal of Orthopaedic Surgery and Research
Background Delayed fracture healing severely impacts patients’ quality of life and imposes economic burdens. Objective This study aimed to investigate the role of miR-328-5p in fracture healing and its underlying molecular mechanisms, providing novel ...
Zhen Han, Chengjian Wei
doaj   +1 more source

Biomechanical Characteristics of Osteoporotic Fracture Healing in Ovariectomized Rats: A Systematic Review.

open access: yesPLoS ONE, 2016
Biomechanical tests are widely used in animal studies on osteoporotic fracture healing. However, the biomechanical recovery process is still unknown, leading to difficulty in choosing time points for biomechanical tests and in correctly assessing ...
Lin Chen   +6 more
doaj   +1 more source

Use of teriparatide in preventing delayed bone healing in complex biosseous leg fracture: a case report [PDF]

open access: yes, 2021
Fracture nonunion is one of the greatest challenges for orthopedic surgeons. We present the case of a young man with a complex open biosseous fracture of the leg who underwent surgery and early systemic pharmacological treatment with teriparatide ...
V. Bottai   +6 more
core   +1 more source

Research progress in the roles of Notch signaling pathway during fracture healing

open access: yesShanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Fracture is the most common large-organ injury in humans. It takes several months or even longer from the onset to the completion of bone reconstruction. In severe cases, delayed healing or even bone discontinuity can occur.
GUO Liqiang, ZHAO Shitian, SHU Bing
doaj   +1 more source

The predictive value of stress-induced hyperglycemia parameters for delayed healing after tibial fracture post-surgery

open access: yesJournal of Orthopaedic Surgery and Research
The objective of this retrospective cohort study was to investigate the predictive value of stress-induced hyperglycemia parameters for delayed healing after tibial fracture post-surgery.
Xiang Ji   +4 more
semanticscholar   +1 more source

Delayed Expression of Circulating TGF-β1 and BMP-2 Levels in Human Nonunion Long Bone Fracture Healing.

open access: yesJournal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2017
BACKGROUND The healing process of bone fracture requires a well-controlled multistage and sequential order beginning immediately after the injury.
Y. Hara   +9 more
semanticscholar   +1 more source

The role of hypertrophic chondrocytes in regulation of the cartilage-to-bone transition in fracture healing

open access: yesBone Reports, 2022
Endochondral bone formation is an important pathway in fracture healing, involving the formation of a cartilaginous soft callus and the process of cartilage-to-bone transition.
Joe Kodama   +4 more
semanticscholar   +1 more source

Demystifying the status of fracture healing using tomosynthesis: A case report

open access: yesRadiology Case Reports, 2015
Radiography is the most common imaging method for assessing the progress of fracture healing. However, accurate assessment may be confounded by fracture complexity in which a combination of anatomic overlay and hypertrophic callous can be visually ...
Eira S. Roth, MD   +2 more
doaj   +1 more source

Time Course of Immune Response and Immunomodulation During Normal and Delayed Healing of Musculoskeletal Wounds

open access: yesFrontiers in Immunology, 2020
Single trauma injuries or isolated fractures are often manageable and generally heal without complications. In contrast, high-energy trauma results in multi/poly-trauma injury patterns presenting imbalanced pro- and anti- inflammatory responses often ...
Preeti J. Muire   +2 more
doaj   +1 more source

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