Results 41 to 50 of about 154,529 (215)

Effect of daily teriparatide for delayed union of fracture neck of the femur

Journal of Orthopedics, Traumatology and Rehabilitation, 2019
Background: Delayed union and nonunion of fracture neck of the femur remains a therapeutic challenge to orthopedic surgeons worldwide which is why this fracture is aptly named as unsolved fracture.
Jitendra Kumar Mishra, Nirmal Chandra Mohapatra, Bikram Keshari Kar   +2 more
doaj   +1 more source

Shear movement at the fracture site delays healing in a diaphyseal fracture model [PDF]

Journal of Orthopaedic Research, 2003
AbstractThis study tested the hypothesis that interfragmentary axial movement of transverse diaphyseal osteotomies would result in improved fracture healing compared to interfragmentary shear movement. Ten skeletally mature merino sheep underwent a mid‐diaphyseal osteotomy of the right tibia, stabilized by external fixation with an interfragmentary gap
Peter, Augat, Johannes, Burger, Sandra, Schorlemmer, Thomas, Henke, Manfred, Peraus, Lutz, Claes   +5 more
openaire   +2 more sources

Modern methods of medication and local therapy for delayed fracture consolidation (literature review)

Гений oртопедии, 2022
Introduction Management of post-traumatic disorders of bone regeneration continues to be a substantial clinical challenge in orthopaedic trauma. These include refracture, nonunion, delayed consolidation.
Rustem I. Sadykov, Ildar F. Akhtyamov
doaj   +1 more source

Bone turnover markers as surrogates of fracture healing after intramedullary fixation of tibia and femur fractures

Bone & Joint Research, 2022
Aims: Bone turnover markers (BTMs) follow distinct trends after fractures and limited evidence suggests differential levels in BTMs in patients with delayed healing.
Christopher C. Stewart, Nathan N. O’Hara, Sofia Bzovsky, Chelsea S. Bahney, Sheila Sprague, Gerard P. Slobogean, On behalf of Vita-Shock Investigators   +6 more
doaj   +1 more source

Deficiency of PDK1 in osteoclasts delays fracture healing and repair

Molecular Medicine Reports, 2020
Bone fractures are common traumatic injuries of the musculoskeletal system. However, delayed union and non‑union fractures are a major clinical problem that present significant socioeconomic burden to patients and the public health sector. The bone‑resorbing osteoclasts and bone‑forming osteoblasts serve important roles in the fracture repair/healing ...
Xiao, Dongliang, Zhou, Quan, Bai, Yiguang, Cao, Baichuan, Zhang, Qiong, Zeng, Gaofeng, Zong, Shaohui   +6 more
openaire   +3 more sources

Early versus delayed hip reduction in the surgical treatment of femoral head fracture combined with posterior hip dislocation: a comparative study

BMC Musculoskeletal Disorders, 2021
Background Few studies focus on the treatment of femoral head fracture combined with posterior hip dislocation, and the safe interval time between injury and hip reduction remains controversial.
Shanxi Wang, Bohua Li, Zhengdong Zhang, Xiaojun Yu, Qin Li, Lei Liu   +5 more
doaj   +1 more source

Gait Analysis to Monitor Fracture Healing of the Lower Leg

Bioengineering, 2023
Fracture healing is typically monitored by infrequent radiographs. Radiographs come at the cost of radiation exposure and reflect fracture healing with a time lag due to delayed fracture mineralization following increases in stiffness.
E. Warmerdam, M. Orth, T. Pohlemann, B. Ganse   +3 more
semanticscholar   +1 more source

The role of oxygen during fracture healing [PDF]

, 2013
Oxygen affects the activity of multiple skeletogenic cells and is involved in many processes that are important for fracture healing. However, the role of oxygen in fracture healing has not been fully studied.
Lu, Chuanyong, Kazakia, Galateia, Williams, Benjamin, Miclau, Theodore, Sinha, Arjun, Decker, Sebastian, Swartz, Harold M, Wang, Xiaodong, Saless, Neema, Hou, Huagang, Hunt, Thomas K, Marcucio, Ralph S   +11 more
core   +1 more source

Rodent animal models of delayed bone healing and non-union formation: a comprehensive review [PDF]

European Cells & Materials, 2013
Despite the growing knowledge on the mechanisms of fracture healing, delayed healing and non-union formation remain a major clinical challenge. Animal models are needed to study the complex process of normal and impaired fracture healing and to develop ...
P Garcia, T Histing, JH Holstein, M Klein, MW Laschke, R Matthys, A Ignatius, B Wildemann, J Lienau, A Peters, B Willie, G Duda, L Claes, T Pohlemann, MD Menger   +14 more
doaj  

Prognostic and therapeutic potential of microRNAs for fracture healing processes and non‐union fractures: A systematic review

Clinical and Translational Medicine, 2023
Background Approximately 10% of all bone fractures result in delayed fracture healing or non‐union; thus, the identification of biomarkers and prognostic factors is of great clinical interest. MicroRNAs (miRNAs) are known to be involved in the regulation
F. Breulmann, L. P. Hatt, B. Schmitz, E. Wehrle, R. G. Richards, E. Della Bella, M. Stoddart   +6 more
semanticscholar   +1 more source