Results 21 to 30 of about 154,529 (215)

High concentrations of several metabolites and growth factors in patients with delayed lower limb fracture healing [PDF]

Гений oртопедии, 2018
Purpose To study concentrations of metabolites and growth factors as well as hematological parameters in patients with delayed lower limb fracture healing Material and methods Concentrations of several metabolites and growth factors as well as ...
Maksim V. Stogov, Anatolii G. Karasev, Elena A. Kireeva, Natalia V. Tushina   +3 more
doaj   +2 more sources

Delayed Fracture Healing in Aged Senescence-Accelerated P6 Mice

Journal of Investigative Surgery, 2012
Osteoporosis is characterized by poor bone quality. However, it is still controversially discussed whether osteoporosis compromises fracture healing. Herein, we studied whether the course of healing of a femur fracture is affected by osteoporosis or age.Using the senescence-accelerated osteoporotic mouse, strain P6 (SAMP6), and a closed femur fracture ...
Tina, Histing, Swantje, Kuntz, David, Stenger, Claudia, Scheuer, Patric, Garcia, Joerg H, Holstein, Moritz, Klein, Tim, Pohlemann, Michael D, Menger   +8 more
openaire   +3 more sources

Scope and Limits of Teriparatide Use in Delayed and Nonunions: A Case Series

Clinics and Practice, 2021
Nonunion is known to occur in up to 10% of all bone fractures. Until recently, the treatment options considered in cases of delayed union and nonunion focused on revision surgery and improvement of local healing.
Petros Ismailidis, Norbert Suhm, Martin Clauss, Annegret Mündermann, Dieter Cadosch   +4 more
doaj   +1 more source

Targeting senescent cells to boost bone fracture healing

The Journal of Clinical Investigation
Bone fracture healing is a complex process with distinct phases: the inflammatory phase, the soft and hard callus formation, and the remodeling phase. In older individuals, bone healing can be delayed or disturbed, leading to non-union fractures at worst.
Lorenz C. Hofbauer, Ulrike Baschant, Christine Hofbauer   +2 more
doaj   +2 more sources

Histological Analysis of Bone Callus in Delayed Union Model Fracture Healing Stimulated with Pulsed Electromagnetic Fields (PEMF)

Scientifica, 2021
Delayed union and nonunion fractures are clinical challenges for orthopedic surgeons. The development of fracture complications, such as delayed union and nonunion fractures, is still difficult to predict.
U. Umiatin, Ismail Hadisoebroto Dilogo, Puji Sari, Sastra Kusuma Wijaya   +3 more
doaj   +1 more source

Radiographic, Biomechanical and Histological Characterization of Femoral Fracture Healing in Aged CD-1 Mice

Bioengineering, 2023
With a gradually increasing elderly population, the treatment of geriatric patients represents a major challenge for trauma and reconstructive surgery.
Maximilian M. Menger, Ruben Manuschewski, Sabrina Ehnert, Mika F. Rollmann, Tanja C. Maisenbacher, Anne L. Tobias, Michael D. Menger, Matthias W. Laschke, Tina Histing   +8 more
doaj   +1 more source

Development of an ischemic fracture healing model in mice

Acta Orthopaedica, 2022
Background and purpose: In fracture healing, ischemia caused by vascular injuries, chronic vascular diseases, and metabolic comorbidities is one of the major risk factors for delayed union and non-union formation.
Maximilian M Menger, Janine Stutz, Sabrina Ehnert, Andreas K Nussler, Mika F Rollmann, Steven C Herath, Benedikt J Braun, Tim Pohlemann, Michael D Menger, Tina Histing   +9 more
doaj   +1 more source

Severe Hemorrhagic Shock Leads to a Delayed Fracture Healing and Decreased Bone Callus Strength in a Mouse Model [PDF]

Clin Orthop Relat Res, 2017
K. Bundkirchen, C. Macke, J. Reifenrath, L. Schäck, S. Noack, B. Relja, Philipp Naber, B. Welke, M. Fehr, C. Krettek, C. Neunaber   +10 more
semanticscholar   +2 more sources

The effect of osteoporosis and its treatment on fracture healing a systematic review of animal and clinical studies

Bone Reports, 2021
Introduction: Osteoporosis is characterised by low bone mass and micro-architectural deterioration of bone structure. Its treatment is directed at the processes of bone formation or resorption, that are of utmost importance in fracture healing.
E.A. Gorter, C.R. Reinders, P. Krijnen, N.M. Appelman-Dijkstra, I.B. Schipper   +4 more
doaj   +1 more source

Dynamization of the plate in treating nonunion of the tibial fracture: Case report

Journal of Orthopaedic Reports, 2023
Background: Plate osteosynthesis for the tibial fracture is one of the alternative treatments with satisfactory outcomes. Appropriate surgical techniques, including an open or minimally invasive approach, absolute or relative stability regarding fracture
Chittawee Jiamton, Pongsakorn Rungchamrussopa, Pariwat Taweekitikul, Techit Leelasestaporn, Theerachai Apivatthakakul   +4 more
doaj   +1 more source