Results 101 to 110 of about 78,171 (296)

Review of NSAID Hypersensitivity Reactions Based on Clinical Phenotyping

open access: yesJournal of Clinical Rheumatology and Immunology
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for their analgesic, antipyretic, and anti-inflammatory properties. However, they are also associated with a broad spectrum of hypersensitivity reactions, ranging from mild cutaneous ...
Cheong Si Leong   +3 more
doaj   +1 more source

The Three R\u27s of Delayed Hypersensitivity

open access: yes, 1974
Delayed hypersensitivity is one of several immune responses initiated by thymus-derived (T) lymphocytes. The mononuclear infiltrate of delayed hypersensitivity is a collaborative phenomenon between T lymphocytes and monocytes.
Horwitz, David
core  

Smoldering Systemic Mastocytosis Without Detectable KIT Mutation: A Debilitating Course and Therapeutic Challenge

open access: yesCancer Nexus, EarlyView.
Graphical abstract illustrating the clinical course and treatment response. ABSTRACT Systemic mastocytosis (SM) is a clonal hematologic neoplasm driven by activating KIT mutations, particularly D816V. Indolent SM typically follows a stable course, progression to higher‐burden subtypes is uncommon.
Homeniuk Anna   +5 more
wiley   +1 more source

Delayed hypersensitivity reactions to diclofenac

open access: yesAllergy, 2003
Allergy
Klingenberg, R. D.   +4 more
openaire   +3 more sources

Induction of Delayed-Type Hypersensitivity to Staphylococcal Antigens in Guinea Pigs

open access: yes, 1978
Delayed-type hypersensitivity against staphylococcal antigens was induced in guinea pigs using Freund's incomplete as well as Freund's complete adjuvant. In animals sensitized with Freund's complete adjuvant the induction time and the duration of delayed-
Jürs Christian Meyer   +5 more
core   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

open access: yesBarrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Lymphocyte Transformation Test (LTT) in Allergy to Benznidazole: A Promising Approach

open access: yesFrontiers in Pharmacology, 2019
Benznidazole (Bzn) from the nitroimidazole family and nifurtimox from nitrofurans family, are drugs used as first and second line treatment for acute and chronic phases of Chagas disease (CD). Even though skin reactions are frequent, confirmed allergy to
M. Andreína Marques-Mejías   +15 more
doaj   +1 more source

Zosteriform spread of herpes simplex virus as a model of recrudescence and its use to investigate the role of immune cells in prevention of recurrent disease

open access: yes, 1984
During the development of a zosteriform rash, which occurs after flank inoculation of BALB/c mice with herpes simplex virus, clinically normal skin becomes infected via nerve endings.
Simmons, Anthony, Nash, Anthony
core  

CELL-MEDIATED-IMMUNITY AND DELAYED-TYPE HYPERSENSITIVITY IN PSEUDOMONAS AERUGINOSA-INFECTED MICE

open access: yes, 1982
In mice repeated systemic injections of Pseudomonas aeruginosa viable cells were able to induce a specific delayed-type hypersensitivity, which was evaluated as increase both in footpad swelling and in the weight of popliteal lymph nodes, after a ...
LOMBARDI S   +5 more
core   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm   +7 more
wiley   +1 more source

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