Results 81 to 90 of about 78,171 (296)

PEG Alternatives in Liposomal Nanocarriers: Physicochemical Characteristics and Sustainable Process Strategies

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The global trend toward sustainable and intensified bioprocesses is driving innovation in the design and scalable synthesis of liposomal nanocarriers, a cornerstone of modern drug delivery. For decades, these nanosystems have relied exclusively on polyethylene glycol (PEG) for their sustained circulation in vivo, but they are currently ...
Chandra Has
wiley   +1 more source

CD69 upregulation on T cells as an in vitro marker for delayed-type drug hypersensitivity

, 2007
BACKGROUND: T cells play a key role in delayed-type drug hypersensitivity reactions. Their reactivity can be assessed by their proliferation in response to the drug in the lymphocyte transformation test (LTT).
W. J. Pichler, L. Zaccaria, B. O. Gerber, A. Beeler, Zaccaria, L, T. Kawabata, Beeler, A, Kawabata, T, Gerber, B O, Pichler, W J   +9 more
core   +1 more source

The Potential Role of Synovial T Cell Infiltration Following Knee Joint Injury in Symptoms and Progression to Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Identification of osteoarthritis (OA)–specific synovial inflammatory pathways and their temporal relevance is critical for therapeutic targeting. We compared mononuclear inflammatory/immune cell responses following joint injury that does or does not lead to OA to define bona fide OA‐associated cellular events.
Babak Moradi, Miriam T. Jackson, Cindy C. Shu, Susan M. Smith, Margaret M. Smith, Sanaa Zaki, Hadrian Platzer, Nils Rosshirt, David Giangreco, Carla R. Scanzello, Christopher B. Little   +10 more
wiley   +1 more source

Suspected Dorzolamide–Induced Delayed Hypersensitivity Blepharitis in Dogs

Acta Veterinaria
The aim was to investigate the incidence, clinical presentation, and potential risk factors for suspected dorzolamide-induced blepharitis (DIB), in dogs diagnosed with glaucoma or hereditary glaucoma predisposition.
Grozdanić Sinisa, Luzhetskii Sergei, Lazić Tatjana, Milčić-Matić Natalija   +3 more
doaj   +1 more source

A simple screening approach to reduce B*5701-associated abacavir hypersensitivity on the basis of sequence variation in HIV reverse transcriptase

, 2007
Background. Abacavir hypersensitivity is strongly associated with the human leukocyte antigen (HLA)–B*5701 allele; however, the cost of routine high-resolution HLA typing before initiation of therapy remains prohibitive.
Chui, C.K.S., Brumme, Z.L., Brumme, C.J., Yip, B., Montaner, J.S.G., Phillips, E.J., Harrigan, P.R.   +6 more
core  

Nifedipine-induced hyporeactivity in delayed hypersensitivity skin tests

, 1987
Four patients and three healthy volunteers were submitted to delayed hypersensitivity skin tests to candidin, tuberculin, streptokinase/streptodornase (SK/SD) and mumps antigen before and after a 1 week treatment with nifedipine 10 mg q. 8h.
Vanhaeverbeek, Michel, Brohée, Dany, Derenne, Fabienne   +2 more
core   +1 more source

Expert Perspectives: Defining and Managing Progressive Pulmonary Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is one of the leading causes of morbidity and mortality in SSc, affecting up to three‐quarters of patients. The disease course is highly heterogeneous, ranging from indolent, nonprogressive forms to rapidly progressive pulmonary fibrosis (PPF).
Devis Benfaremo, Dinesh Khanna, Corrado Campochiaro, Vincent Cottin, Fabrizio Luppi, Marco Matucci‐Cerinic, Gianluca Moroncini, Yannick Allanore   +7 more
wiley   +1 more source

Effect of treatment with cyclophosphamide in low doses upon the onset of delayed type hypersensitivity in mice chronically infected with Trypanosoma cruzi: involvement of heart interstitial dendritic cells

Memorias do Instituto Oswaldo Cruz, 2013
Acute infection with Trypanosoma cruzi results in intense myocarditis, which progresses to a chronic, asymptomatic indeterminate form. The evolution toward this chronic cardiac form occurs in approximately 30% of all cases of T.
Torriceli Souza The, Renata Siqueira Portella, Marcos Lazaro Guerreiro, Sonia Gumes Andrade   +3 more
doaj   +1 more source

Delayed hypersensitivity reactions to iodinated contrast media: A diagnostic approach by skin tests

, 2023
Background: Adverse drug reactions to iodinated contrast media (ICM) have risen due to their increasing use in x-ray-based imaging modalities. Delayed hypersensitivity reactions are mainly caused by nonionic monomeric compounds and represent an issue ...
Biondi, Filippo, Casciola, Gabriele, Cataldo Patruno, Tramontana, Marta, Tommaso Galeotti, Hansel, Katharina, Filippo Biondi, Rossella Marietti, Napolitano, Maddalena, Katharina Hansel, Gabriele Casciola, Bianchi, Leonardo, Maddalena Napolitano, Patruno, Cataldo, Luca Stingeni, Caroppo, Elena Sofia, Galeotti, Tommaso, Leonardo Bianchi, Elena Sofia Caroppo, Marta Tramontana, Stingeni, Luca, Marietti, Rossella   +21 more
core   +1 more source

Auditory Sensitivity in Autism: A Systematic Review of Mismatch Negativity and Mismatch Field Responses

Autism Research, EarlyView.
ABSTRACT Auditory mismatch responses—mismatch negativity (MMN) and mismatch fields (MMF)—are well established electrophysiological markers of automatic auditory discrimination supported by short‐term sensory memory. These responses, typically elicited using passive oddball paradigms, are increasingly used to investigate sensory and language processing ...
Sara Cacciato‐Salcedo, Shreya Jaokar, Neil J. Ingham, Manuel S. Malmierca, Marija M. Petrinovic   +4 more
wiley   +1 more source