Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens. [PDF]
, 1987 We have employed the guinea pig model of L. pneumophila infection, which mimics Legionnaires' disease in humans both clinically and pathologically, to study humoral and cell-mediated immune responses to L.
Breiman, RF, Horwitz, MA
core
Immersive Composition for Sensory Rehabilitation: 3D Visualisation, Surround Sound, and Synthesised Music to Provoke Catharsis and Healing [PDF]
, 2014 There is a wide range of sensory therapies using sound, music and visual stimuli. Some focus on soothing or distracting stimuli such as natural sounds or classical music as analgesic, while other approaches emphasize the active performance of producing ...
A. Cohen +9 more
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Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions
Advanced Science, EarlyView.This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang +4 more
wiley +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Mechanisms conferring sensitivity to low dose radiation exposure and consideration of potentially sensitivie individuals [PDF]
, 2009 No description ...
Jeggo, Penny
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Splenic CD8(+) T cells secrete TGF-beta 1 to exert suppression in mice with anterior chamber-associated immune deviation [PDF]
, 2009 Background CD8(+) regulatory T cells (Treg) have been considered to be involved in a model of ocular-induced tolerance, known as anterior chamber-associated immune deviation (ACAID).
He, H. +6 more
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Advanced Science, EarlyView.This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo +19 more
wiley +1 more source
Allergy, Asthma & Clinical Immunology, 2018 Background Recombinant human erythropoietin, such as epoetin alfa and darbepoetin alfa, is an important therapy for anemia due to chronic renal failure. Allergy to recombinant human erythropoietin and the need for desensitization are rare.
Jaime S. Rosa +3 more
doaj +1 more source
Humoral immune response and delayed type hypersensitivity to influenza vaccine in patients with diabetes mellitus [PDF]
, 1987 The antibody response and delayed type hypersensitivity reaction to commercially available trivalent influenza vaccine in 159 patients with diabetes mellitus was compared with response and reaction in 28 healthy volunteers.
A Ennis +29 more
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AGING MEDICINE, EarlyView.Geriatric asthmatics exhibit more comorbidities, poorer lung function, higher neutrophil ratios, and elevated CRP levels. ABSTRACT Objective The research analyzed the clinical characteristics of geriatric and nongeriatric asthma cases, aiming to provide new insights into the diagnosis and management of geriatric asthma for clinicians.
Mengxia Gu +4 more
wiley +1 more source