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Delayed Drug Hypersensitivity Reactions: Molecular Recognition, Genetic Susceptibility, and Immune Mediators

open access: yesBiomedicines, 2023
Drug hypersensitivity reactions are classified into immediate and delayed types, according to the onset time. In contrast to the immediate type, delayed drug hypersensitivity mainly involves T lymphocyte recognition of the drug antigens and cell ...
Mu-Tzu Chu   +3 more
doaj   +2 more sources

Evolocumab-induced delayed skin hypersensitivity reaction in a patient with familial hypercholesterolaemia

open access: yesAlergologia Polska
In this report, we describe a patient with a delayed cutaneous hypersensitivity reaction to evolocumab, a human monoclonal antibody directed against the serine protease proprotein convertase subtilisin/kexin type 9 used to reduce low-density lipoprotein ...
Grzegorz Porebski, Alicja Dziadowiec
doaj   +2 more sources

Delayed hypersensitivity reaction to allopurinol: A case report. [PDF]

open access: yesMalays Fam Physician, 2023
Allopurinol is the well-known first-line treatment option for symptomatic hyperuricaemia and gout. It is cost-effective particularly for the management of chronic gout.
Mohammad CM   +5 more
europepmc   +3 more sources

IMMEDIATE AND DELAYED HYPERSENSITIVITY REACTIONS TO LATEX GLOVES IN A DENTAL STUDENT. A case report. [PDF]

open access: yesJournal of IMAB, 2011
The article presents a case of dental student with immediate and delayed hypersensitivity reaction to latex gloves. Symptoms appeared during the second year of regularly using of latex gloves.
Iliyana Stoeva
doaj   +2 more sources

Delayed and immediate hypersensitivity reactions associated with the use of amalgam

open access: yes, 2000
Hypersensitivity to the constituents of dental amalgam is uncommon. When it occurs it typically manifests itself as a lichenoid reaction involving a delayed, type IV, cell-mediated hypersensitivity response.
Pemberton, Michael, McGivern, B.
core   +8 more sources

Delayed hypersensitivity reaction after oral intake of non-ionic iodinated contrast medium. [PDF]

open access: yes, 2021
Following intravenous contrast medium (CM) injection, a small proportion of patients acquires hypersensitivity reactions that occur either immediately or non-immediately (delayed).
Peters, Alan A.   +5 more
core   +2 more sources

Perspective of delayed Hypersensitivity: A review [PDF]

open access: yes, 2022
T cells enter tissues and are activated by antigen-presenting cells to produce cytokines that cause inflammation in the local area. In allergic contact dermatitis, drug eruptions, asthma, and autoimmune disorders, CD8+ T lymphocytes mediate DTH reactions.
Johnkennedy, N. (Nnodim)   +8 more
core   +1 more source

Delayed-type hypersensitivity skin reaction to Covid-19 vaccine

open access: yesJournal of Family Medicine and Primary Care, 2021
Delayed-Type Hypersensitivity Skin Reaction following the Moderna mRNA COVID-19 Vaccine. This case is an unusually prolonged presentation of skin rash following vaccination for the novel COVID-19 virus.
Mia L Robb, Leo J Robb
doaj   +1 more source

Carbamazepine-associated drug reaction with eosinophilia and systemic symptoms syndrome

open access: yesJournal of Pediatric Neurosciences, 2021
Drug reaction with eosinophilia and systemic symptoms syndrome is a severe type IV (delayed T-cell-dependent reaction) hypersensitivity reaction, characterized by fever, mucocutaneous eruptions, eosinophilia, and systemic inflammatory involvement.
Ankush Sharma   +3 more
doaj   +1 more source

Predominant patterns of β-lactam hypersensitivity in a single German Allergy Center: exanthem induced by aminopenicillins, anaphylaxis by cephalosporins

open access: yesAllergy, Asthma & Clinical Immunology, 2020
Background Penicillins and other β-lactam antibiotics are the most common elicitors of allergic drug reaction. However, data on the pattern of clinical reaction types elicited by specific β-lactams are scarce and inconsistent.
Philipp Schrüfer   +3 more
doaj   +1 more source

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