Results 101 to 110 of about 72,472 (321)

Gender‐Affirming Feminization Voice Surgery: A Scoping Review of Preoperative Assessments

The Laryngoscope, EarlyView.
PRISMA flowchart. ABSTRACT Objective To identify the preoperative assessments and criteria surgeons use to assess the suitability of transfeminine patients for voice feminization surgery. Data Sources Electronic search of Ovid MEDLINE, Ovid Embase, APA PsycINFO, Cochrane Library, CINAHL, and PubMed excluding MEDLINE records was performed on February 11,
Jadin Chahade, Hedieh Keshavars, Janice Y. Kung, Teresa L. D. Hardy, Caroline C. Jeffery   +4 more
wiley   +1 more source

Association between the onset age of puberty and parental height.

PLoS ONE, 2019
BACKGROUND:The onset age of physiological puberty is greatly variable. This variability has been attributed to environmental factors and to genetic factors although a very little is explained by genome-wide associations studies.
Yehuda Limony, Slawomir Koziel, Michael Friger   +2 more
doaj   +1 more source

Gain of function mutants: Ion channels and G protein-coupled receptors [PDF]

, 2000
Many ion channels and receptors display striking phenotypes for gain-of-function mutations but milder phenotypes for null mutations. Gain of molecular function can have several mechanistic bases: selectivity changes, gating changes including constitutive
Karschin, Andreas, Lester, Henry A.
core   +1 more source

IGSF10 mutations dysregulate gonadotropin‐releasing hormone neuronal migration resulting in delayed puberty

EMBO Molecular Medicine, 2016
Early or late pubertal onset affects up to 5% of adolescents and is associated with adverse health and psychosocial outcomes. Self‐limited delayed puberty (DP) segregates predominantly in an autosomal dominant pattern, but the underlying genetic ...
Sasha R Howard, Leonardo Guasti, Gerard Ruiz‐Babot, Alessandra Mancini, Alessia David, Helen L Storr, Lousie A Metherell, Michael JE Sternberg, Claudia P Cabrera, Helen R Warren, Michael R Barnes, Richard Quinton, Nicolas de Roux, Jacques Young, Anne Guiochon‐Mantel, Karoliina Wehkalampi, Valentina André, Yoav Gothilf, Anna Cariboni, Leo Dunkel   +19 more
doaj   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Differences in female athlete triad risk factors between Japanese and American female runners: A comparative study

PM&R, EarlyView.
Abstract Background Differences in female athlete triad risk factors between runners from Japan and the United States have not been explored. Objective To compare the prevalence of Triad risk factors and Triad components between female Japanese and American distance runners. Design Observational, cross‐sectional.
Ana Carla C. Salamunes, Natsue Koikawa, Nancy I. Williams, Kristen J. Koltun, Maha L. Vijaya Krishnan, Yuko Sakurama, Takao Matsuda, Shihoko Suzuki, Yuji Takazawa, Mary Jane De Souza   +9 more
wiley   +1 more source

Nanoplastics Impair GnRH Neuron Migration and Neuroendocrine Function: Emerging Players in the Pathogenesis of Reproductive Disorders

Small, EarlyView.
Little is known about the effects of polystyrene nanoplastics (PS‐NPs) on gonadotropin releasing hormone (GnRH) neurons, which control puberty onset and fertility. By applying tailored in vitro GnRH neuron models, this article shows how PS‐NPs are internalized and impact hormone secretion and cell migration, through gene expression changes. Ultimately,
Federica Amoruso, Alyssa Julia Jennifer Paganoni, Astrid Saraceni, Andrea Magnani, Alessia Brossa, Giorgio Roberto Merlo, Cristina Matei, Ruben Heinjan Willemsen, Raíssa Carneiro Rezende, Alexander Augusto de Lima Jorge, Federica Dal Bello, Patrizia Bovolin, Sasha Rose Howard, Roberto Oleari, Anna Cariboni   +14 more
wiley   +1 more source

Insulin-like growth factor 1 and sex hormones for assessment of anthropometric and pubertal growth of Egyptian children and adolescents with type 1 diabetes mellitus (single center study)

BMC Endocrine Disorders
Background This study aimed to assess the anthropometric measures and pubertal growth of children and adolescents with Type 1 diabetes mellitus (T1DM) and to detect risk determinants affecting these measures and their link to glycemic control.
Rasha A. Thabet, Eman M. Sherif, Ahmed O Abd ElAal, Rana A. Mahmoud   +3 more
doaj   +1 more source

The importance of elementary sexuality education [PDF]

, 2002
Includes bibliographical ...
Meillier, Jill M.
core  

A study of seasonally delayed puberty in the male hare, Lepus europaeus [PDF]

, 1976
G. A. Lincoln, P. C. B. MacKinnon
openalex   +1 more source