Results 11 to 20 of about 584,122 (264)

Delayed puberty [PDF]

open access: yesJournal of Clinical Endocrinology & Metabolism, 1996
Delayed puberty can be defined as the absence of any signs of puberty in subjects that have attained an age at the upper limit (+2DS) for the onset of puberty, that means 13 years in girls and 14 years in boys. The causes of delayed puberty can be classified into three groups, functional temporary impairment in gonadotropin and sex steroid secretion ...
ANTONIAZZI, Franco   +2 more
core   +7 more sources

Genetic Evaluation of Patients With Delayed Puberty and Congenital Hypogonadotropic Hypogonadism: Is it Worthy of Consideration?

open access: yesFrontiers in Endocrinology, 2020
Delayed puberty is a common reason of pediatric endocrinological consultation. It is often a self-limited (or constitutional) condition with a strong familial basis. The type of inheritance is variable but most commonly autosomal dominant.
Adalgisa Festa   +3 more
doaj   +2 more sources

Delayed puberty versus hypogonadism: a challenge for the pediatrician [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism, 2018
Constitutional delay of growth and puberty (CDGP) is the most common cause of delayed puberty (DP), is mainly found in males, and is characterized by short stature and delayed skeletal maturation.
Mauro Bozzola   +5 more
doaj   +5 more sources

Testosterone undecanoate treatment for muscle weakness in a male with hypogonadotropic hypogonadism delayed puberty: A case report [PDF]

open access: yesJKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2022
Puberty is a series of physical development and sexual maturation that aims to achieved reproductive capacity. The hypothalamic-pituitary-gonadal (HPG) axis has an important role in the normal process of puberty.
Dicky Moch Rizal, Nandia Septiyorini
doaj   +2 more sources

From biological marker to clinical application: the role of anti-Müllerian hormone for delayed puberty and idiopathic non-obstructive azoospermia in males [PDF]

open access: yesEndocrine Connections
Anti-Müllerian hormone (AMH), a biomarker secreted by Sertoli cells in the testes, has emerged as a critical indicator of male reproductive function with significant clinical application potential.
Yuanyuan Zeng   +3 more
doaj   +2 more sources

Unraveling Delayed Puberty: A Rare Case of Congenital Hypogonadotropic Hypogonadism Masked by Celiac Disease and Plummer–Vinson Syndrome [PDF]

open access: yesClinical Case Reports
Congenital hypogonadotropic hypogonadism (CHH) is a rare disorder that results in delayed puberty and infertility due to impaired secretion of gonadotropin‐releasing hormone (GnRH).
Osama Ahmad   +7 more
doaj   +2 more sources

IGSF10 mutations dysregulate gonadotropin‐releasing hormone neuronal migration resulting in delayed puberty

open access: yesEMBO Molecular Medicine, 2016
Early or late pubertal onset affects up to 5% of adolescents and is associated with adverse health and psychosocial outcomes. Self‐limited delayed puberty (DP) segregates predominantly in an autosomal dominant pattern, but the underlying genetic ...
Sasha R Howard   +19 more
doaj   +2 more sources

Delayed Puberty and Its Association With Hormonal Changes in Children With Chronic Renal Insufficiency

open access: yesActa Medica Iranica, 2022
Chronic kidney diseases affect sex hormones, and thus it is now hypothesized abnormal puberty phenomenon in adolescents suffering renal failure. The primary study endpoint was to assess the frequency of disorders related to the clinical incidence of ...
Davood Amirkashani   +2 more
doaj   +1 more source

Role of the GH-IGF1 axis on the hypothalamus–pituitary–testicular axis function: lessons from Laron syndrome

open access: yesEndocrine Connections, 2021
Background: Animal studies suggest that insulin-like growth factor 1 (IGF1 ) may influence the function of the hypothalamus–pituitary–testicular axis, especially in childhood, but the evidence in humans is scanty.
Rossella Cannarella   +4 more
doaj   +1 more source

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