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Journal of Clinical Endocrinology & Metabolism, 1996 Delayed puberty can be defined as the absence of any signs of puberty in subjects that have attained an age at the upper limit (+2DS) for the onset of puberty, that means 13 years in girls and 14 years in boys. The causes of delayed puberty can be classified into three groups, functional temporary impairment in gonadotropin and sex steroid secretion ...
ANTONIAZZI, Franco +2 more
core +7 more sources
Delayed puberty versus hypogonadism: a challenge for the pediatrician [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2018 Constitutional delay of growth and puberty (CDGP) is the most common cause of delayed puberty (DP), is mainly found in males, and is characterized by short stature and delayed skeletal maturation.
Mauro Bozzola +5 more
doaj +5 more sources
Frontiers in Endocrinology, 2020 Delayed puberty is a common reason of pediatric endocrinological consultation. It is often a self-limited (or constitutional) condition with a strong familial basis. The type of inheritance is variable but most commonly autosomal dominant.
Adalgisa Festa +3 more
doaj +2 more sources
From biological marker to clinical application: the role of anti-Müllerian hormone for delayed puberty and idiopathic non-obstructive azoospermia in males [PDF]
Endocrine ConnectionsAnti-Müllerian hormone (AMH), a biomarker secreted by Sertoli cells in the testes, has emerged as a critical indicator of male reproductive function with significant clinical application potential.
Yuanyuan Zeng +3 more
doaj +2 more sources
Unraveling Delayed Puberty: A Rare Case of Congenital Hypogonadotropic Hypogonadism Masked by Celiac Disease and Plummer–Vinson Syndrome [PDF]
Clinical Case ReportsCongenital hypogonadotropic hypogonadism (CHH) is a rare disorder that results in delayed puberty and infertility due to impaired secretion of gonadotropin‐releasing hormone (GnRH).
Osama Ahmad +7 more
doaj +2 more sources
Genetic, epigenetic and enviromental influencing factors on the regulation of precocious and delayed puberty [PDF]
Frontiers in Endocrinology, 2022 Stefania de Santis +2 more
exaly +2 more sources
Acta Medica Iranica, 2022 Chronic kidney diseases affect sex hormones, and thus it is now hypothesized abnormal puberty phenomenon in adolescents suffering renal failure. The primary study endpoint was to assess the frequency of disorders related to the clinical incidence of ...
Davood Amirkashani +2 more
doaj +1 more source
DeckerMed Family Medicine, 2020 Although common, delayed puberty can be distressing to patients and families. Careful assessment is necessary to ensure appropriate physical and social development in patients that require intervention to reach pubertal milestones and achieve optimal growth.
Jessica Schmitt, Paul Boepple
+4 more sources
A Shared Genetic Basis for Self-Limited Delayed Puberty and Idiopathic Hypogonadotropic Hypogonadism [PDF]
, 2016 Background: Delayed puberty is a common condition and, in the absence of an underlying condition, is self-limited in most cases. Though delayed puberty appears to be heritable, no specific genetic cause has yet been reported.
Zhu, Jia
core +6 more sources
Endocrine Connections, 2021 Background: Animal studies suggest that insulin-like growth factor 1 (IGF1 ) may influence the function of the hypothalamus–pituitary–testicular axis, especially in childhood, but the evidence in humans is scanty.
Rossella Cannarella +4 more
doaj +1 more source