Frontiers in Endocrinology, 2020 Delayed puberty is a common reason of pediatric endocrinological consultation. It is often a self-limited (or constitutional) condition with a strong familial basis. The type of inheritance is variable but most commonly autosomal dominant.
Adalgisa Festa +3 more
doaj +2 more sources
Exposure to heavy metals, bisphenol A, and phthalates: Implications for precocious or delayed puberty. [PDF]
PLoS ONEThis study examined the associations between exposure to heavy metals, bisphenol A (BPA), and phthalates and precocious or delayed puberty. This study was a cross-sectional study using the data obtained from the Korea Environmental Exposure and Health ...
Seung-Ah Choe, Eunjung Kim, Mina Ha
doaj +2 more sources
Frequency of Delayed Puberty in Boys with Contemporary Management of Duchenne Muscular Dystrophy [PDF]
JCRPEINTRODUCTION: Delayed puberty is thought to be common in boys with Duchenne muscular dystrophy (DMD) treated with long term oral glucocorticoid. The aim of this study was to report the frequency of delayed puberty in DMD from examination by a paediatric ...
Sarah McCarrison +6 more
doaj +2 more sources
Clinical approach to the male with delayed puberty [PDF]
Archives of Endocrinology and MetabolismDisorders of pubertal onset and progression are a common cause for referral to paediatric endocrinologists, with delayed puberty in males being particularly frequent. Pubertal development depends on the hypothalamic-pituitary-testicular (HPT) axis, which
Rodolfo A. Rey +2 more
doaj +2 more sources
Adult Consequences of Self-Limited Delayed Puberty
Pediatrics, 2017 Delayed puberty is a common condition defined as the lack of sexual maturation by an age ≥2 SD above the population mean. In the absence of an identified underlying cause, the condition is usually self-limited.
Jia Zhu, Yee-Ming Chan
exaly +2 more sources
Deleterious variants in intolerant genes reveal new candidates for self-limited delayed puberty. [PDF]
Eur J EndocrinolOBJECTIVE: Self-limited delayed puberty (SLDP) is the most common cause of delayed puberty and exhibits high heritability, although few causal genes have been identified. This study aims to identify potential candidate genes associated with SLDP. METHODS:
Rezende RC +22 more
europepmc +2 more sources
Delayed and Precocious Puberty: Genetic Underpinnings and Treatments
Endocrinology and Metabolism Clinics of North America, 2020 Delayed puberty may signify a common variation of normal development, or indicate the presence of a pathologic process. Constitutional delay of growth and puberty is a strongly familial type of developmental pattern and accounts for the vast majority of ...
Anisha Gohil, Erica A Eugster
exaly +2 more sources
Next-generation sequencing approach in the diagnosis of delayed puberty
Current Opinion in Endocrine and Metabolic Research, 2020 © 2020 Elsevier Ltd The inheritance of pubertal timing is strongly influenced by genetic regulators, with conditions of delayed or absent puberty segregating within families often with Mendelian inheritance patterns.
Tansit Saengkaew, Sasha R Howard
exaly +2 more sources
Delayed Puberty in Girls with Primary Amenorrhea: A Report of Cases
Journal of Biomedicine and Translational Research, 2021 Background:Female puberty starts when the pituitary hormone producing follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which will stimulate the ovaries to produce estrogen.
Fatinah Shahab +4 more
doaj +3 more sources
From biological marker to clinical application: the role of anti-Müllerian hormone for delayed puberty and idiopathic non-obstructive azoospermia in males [PDF]
Endocrine ConnectionsAnti-Müllerian hormone (AMH), a biomarker secreted by Sertoli cells in the testes, has emerged as a critical indicator of male reproductive function with significant clinical application potential.
Yuanyuan Zeng +3 more
doaj +2 more sources