Results 21 to 30 of about 71,302 (277)

Enhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axis [PDF]

open access: yes, 2007
The initiation of mammalian puberty and the maintenance of female reproductive cycles are events controlled by hypothalamic neurons that secrete the decapeptide gonadotropin-releasing hormone (GnRH).
Sabine Heger   +56 more
core   +1 more source

Evo-devo of human adolescence: beyond disease models of early puberty [PDF]

open access: yes, 2013
Despite substantial heritability in pubertal development, much variation remains to be explained, leaving room for the influence of environmental factors to adjust its phenotypic trajectory in the service of fitness goals.
A Templeton   +69 more
core   +2 more sources

Delayed Puberty in Girls with Primary Amenorrhea: A Report of Cases

open access: yesJournal of Biomedicine and Translational Research, 2021
Background:Female puberty starts when the pituitary hormone producing follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which will stimulate the ovaries to produce estrogen.
Fatinah Shahab   +4 more
doaj   +1 more source

Mutational analysis of DAX1 in patients with hypogonadotropic hypogonadism or pubertal delay [PDF]

open access: yes, 1999
Although delayed puberty is relatively common and often familial, its molecular and pathophysiologic basis is poorly understood. In contrast, the molecular mechanisms underlying some forms of hypogonadotropic hypogonadism (HH) are clearer, following the ...
Achermann, JC   +12 more
core   +1 more source

Height and timing of growth spurt during puberty in young people living with vertically acquired HIV in Europe and Thailand. [PDF]

open access: yes, 2019
OBJECTIVE: The aim of this study was to describe growth during puberty in young people with vertically acquired HIV. DESIGN: Pooled data from 12 paediatric HIV cohorts in Europe and Thailand.
Abou-Rayyah, ACM   +436 more
core   +4 more sources

Functional hypogonadism in adolescence: an overlooked cause of secondary hypogonadism

open access: yesEndocrine Connections, 2023
Hypogonadism is a clinical syndrome resulting from failure to produce physiological concentrations of sex steroid hormones with accompanying symptoms, such as slowed growth and delayed pubertal maturation.
Rebeca Esquivel-Zuniga, Alan D Rogol
doaj   +1 more source

Reproductive and developmental effects of phthalate diesters in females. [PDF]

open access: yes, 2013
Phthalate diesters, widely used in flexible plastics and consumer products, have become prevalent contaminants in the environment. Human exposure is ubiquitous and higher phthalate metabolite concentrations documented in patients using medications with ...
Chambers, Christina   +2 more
core   +1 more source

The relationship between obesity and body compositions with respect to the timing of puberty in Chongqing adolescents: a cross-sectional study

open access: yesBMC Public Health, 2017
Background It is well known that excess adiposity during childhood may influence pubertal development. However, the extent to which body compositions vary in throughout puberty in boys and girls is currently unknown.
Fang He   +5 more
doaj   +1 more source

Testosterone Replacement Therapy in Adolescents With Sickle Cell Disease Reverses Hypogonadism Without Promoting Priapism: A Case Report

open access: yesUrology Case Reports, 2015
Delayed puberty secondary to hypogonadism is commonly seen in sickle cell disease (SCD), affecting normal growth and development. The condition is rarely treated in SCD for fear of inducing priapism episodes.
Belinda F. Morrison   +3 more
doaj   +1 more source

Novas perspectivas no diagnóstico do hipogonadismo pediátrico masculino: a importância do AMH como marcador de células de Sertoli [PDF]

open access: yes, 2011
Sertoli cells are the most active cell population in the testis during infancy and childhood. In these periods of life, hypogonadism can only be evidenced without stimulation tests, if Sertoli cell function is assessed.
Grinspon, Romina, Rey, Rodolfo Alberto
core   +2 more sources

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