Results 41 to 50 of about 72,472 (321)

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. [PDF]

, 2014
Age at menarche is a marker of timing of puberty in females. It varies widely between individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, cardiovascular disease, breast cancer and all-cause mortality.
A Kong, A Lomniczi, A Murphy, A Schröder, AA D’Aloisio, Aarno Palotie, AB Migliano, Adamo Pio D’adamo, Aida K. Dieffenbach, AL Dixon, Albert Hofman, Albert V. Smith, Albertine J. Oldehinkel, Alexander Teumer, Alison M. Dunning, Andrea D. Coviello, Andrea Ganna, Andres Metspalu, Andrew C. Heath, Andrew D. Johnson, André G. Uitterlinden, Angela Cox, Anja Rudolph, Anna M. Storniolo, Anna Murray, Anneli Pouta, Annika Lindblom, Antonietta Robino, AP Abreu, Arto Mannermaa, AS Dimas, AV Segrè, B Kabakchiev, B Zhang, BE Stranger, Behrooz Z. Alizadeh, Ben A. Oostra, Bernardo Bonanni, Bjarke Feenstra, BP Fairfax, Bruce H. R. Wolffenbuttel, C Colantuoni, C Liu, C-J Partsch, Carl Blomqvist, Catharina A. Hartman, Cathy E. Elks, CE Elks, Christian Gieger, Chunyan He, CJ Willer, Cornelia M. van Duijn, CP Schaaf, Craig E. Pennell, D Mehta, D Sasayama, DA Cusanovich, Daniel F. Gudbjartsson, Daniel I. Chasman, Daniel L. Koller, David Couper, David J. Hunter, David Karasik, David P. Strachan, David Schlessinger, Debbie Lawlor, Deborah J. Thompson, Diana L. Cousminer, Dieter Flesch-Janys, Diether Lambrechts, Dirkje S. Postma, DM Greenawalt, Doris Stöckl, Dorret I. Boomsma, Douglas F. Easton, Douglas P. Kiel, E Grundberg, E Grundberg, E Grundberg, Eco E. J. de Geus, EE Schadt, EK Speliotes, EL Heinzen, Eleonora Porcu, Elisabeth Widen, Elizabeth A. Streeten, Ellen A. Nohr, Ellen W. Demerath, Emmi Tikkanen, Enda M. Byrne, Eric Boerwinkle, Erik Ingelsson, Erin K. Wagner, Eva Albrecht, Evelin Mihailov, F Innocenti, F Nagl, F Zou, Felix Day, Femke Atsma, Fergus J. Couch, Fernando Rivadeneira, Frank B. Hu, Frank Geller, GA Heap, George Davey Smith, George McMahon, Georgia Chenevix-Trench, Gerard Waeber, Gisli Masson, Gonneke Willemsen, Graham G. Giles, Grant W. Montgomery, Gudmar Thorleifsson, Gudny Eiriksdottir, H Lango Allen, H-J Westra, Harold Snieder, Heather A. Boyd, Heli Nevanlinna, Henri Wallaschofski, Henrik Flyger, Henry Völzke, Hermann Brenner, HHH Göring, Hiltrud Brauch, Hoda Anton-Culver, IK Temple, Ilja M. Nolte, Immaculata De Vivo, Irene L. Andrulis, J Ding, J Huang, J Yang, J Yang, J Yang, J. Margriet Collée, JA Webster, Javier Benitez, JC Barrett, Jenny A. Visser, Jenny Chang-Claude, JF Degner, Jing Hua Zhao, Jinhui Chen, Joanne M. Murabito, Joe Dennis, Johan G. Eriksson, John L. Hopper, John P. Rice, John R. B. Perry, Jonathan Tyrer, Jouke-Jan Hottenga, JR Gibbs, Julia A. Knight, Julian Peto, Julie E. Buring, K Estrada, K Hao, K Michailidou, Kamila Czene, Kari Stefansson, Kathryn L. Lunetta, Katri Pylkäs, Kay-Tee Khaw, Ken K. Ong, KS Kompass, Kyriaki Michailidou, L Liang, Laura Crisponi, Laura J. Bierut, Laura M. Yerges-Armstrong, Lavinia Paternoster, LB Barreiro, LFG Silveira, Lili Milani, Lisette Stolk, Lude Franke, Luigi Ferrucci, Lynda M. Rose, M Horikoshi, M Rantalainen, Maartje J. Hooning, Mads Melbye, Manjeet K. Bolla, Marek Zygmunt, Margaret J. Wright, Marjanka K. Schmidt, Marjo-Riitta Järvelin, Mark I. McCarthy, Massimo Mangino, Matthias W. Beckmann, Meir J. Stampfer, Melanie Waldenberger, Melissa E. Garcia, Mellissa C. Southey, Michael J. Econs, Montserrat García-Closas, Munro Peacock, N Ruf, Najaf Amin, Nancy L. Pedersen, Natalia Tšernikova, Nicholas G. Martin, Nicholas J. Timpson, Nicholas J. Wareham, Nora Franceschini, P Prentice, Paolo Gasparini, Paolo Peterlongo, Paolo Radice, Pascal Guénel, Patrick F. McArdle, Patrick Neven, Patrick Sulem, Patrik K. Magnusson, Paul D. P. Pharoah, Paul M. Ridker, Per Hall, Peter A. Fasching, Peter Devilee, Peter Kraft, Peter Vollenweider, Q Li, Qin Wang, Reedik Mägi, Robert Winqvist, Robin Haring, Roger L. Milne, RP Grinspon, RS Huang, RSN Fehrmann, Ruth J. F. Loos, S Cho, S Constantin, S Sulzbacher, Sandra Lai, Sanela Kjellqvist, SE Parker, Serena Sanna, Sheila Ulivi, Stefania Bandinelli, Stephen Chanock, Stig E. Bojesen, Suiqun Guo, Susan Ring, Sven Bergmann, T Kwan, T Maeda, T Zeller, Tamara B. Harris, Tanguy Corre, Tatiana Foroud, Teresa Ferreira, Thorkild I. A. Sørensen, Tim D. Spector, Tune H. Pers, Tõnu Esko, Ulla Sovio, Unnur Thorsteinsdottir, Ute Hamann, V Emilsson, Veikko Salomaa, Veli-Matti Kosma, Vilmundur Gudnason, W Zheng, Wei Q. Ang, Wendy L. McArdle, Y Idaghdour, Y Stelzer, Z Zadik, Zoltan Kutalik   +271 more
core   +7 more sources

Constitutional delay of growth and puberty in boys: review

Mìžnarodnij Endokrinologìčnij Žurnal, 2019
The review focuses on the diagnosis, clinical and general therapeutic approach to constitutional growth and delayed puberty and hypogonadotrophic hypogonadism in men, which are difficult to distinguish. Clinical history and physical examination should be
A.B. Grossman, S.I. Ismailov, M.G. Kulmirzayeva, Y.M. Urmanova, K.N. Gilazitdinov   +4 more
doaj   +1 more source

Delayed puberty versus hypogonadism: a challenge for the pediatrician [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2018
Constitutional delay of growth and puberty (CDGP) is the most common cause of delayed puberty (DP), is mainly found in males, and is characterized by short stature and delayed skeletal maturation.
Mauro Bozzola, Elena Bozzola, Chiara Montalbano, Filomena Andreina Stamati, Pietro Ferrara, Alberto Villani   +5 more
doaj   +1 more source

A classification of genes involved in normal and delayed male puberty

Asian Journal of Andrology, 2023
Puberty is a pivotal biological process that completes sexual maturation to achieve full reproductive capability. It is a major transformational period of life, whose timing is strongly affected by genetic makeup of the individual, along with various ...
Maleeha Akram, Syed Shakeel Raza Rizvi, Mazhar Qayyum, David J Handelsman   +3 more
doaj   +1 more source

Sex assignment in conditions affecting sex development [PDF]

, 2017
The newborn infant with atypical genitalia presents a challenging clinical scenario and requires expert input. There have been appreciable advances in our knowledge of the underlying causes that may lead to a mere difference or a more serious disorder of
Ahmed, S. Faisal, Markosyan, Renata
core   +1 more source

Introduction to and Screening Visit Results of the Multicenter Pediatric Crohn's Disease Growth Study. [PDF]

, 2020
BackgroundStatural growth impairment is more common in males with Crohn's disease (CD). We assessed sex differences in height Z score differences and bone age (BA) Z scores and characterized age of menarche in a novel contemporary cohort of pediatric CD ...
Andrews, Howard, Gokhale, Ranjana, Goyal, Alka, Gupta, Neera, Guthery, Stephen, Keljo, David, Leu, Cheng-Shiun, Lustig, Robert H, Patel, Ashish S, Sylvester, Francisco   +9 more
core  

Maternal pre-pregnancy obesity and timing of puberty in sons and daughters: a population-based cohort study. [PDF]

, 2019
BackgroundIn many countries, an increased prevalence of obesity in pregnancy has coincided with a declining pubertal age. We aimed to explore the potential effect of maternal pre-pregnancy overweight and obesity on timing of puberty in sons and daughters.
Arah, Onyebuchi A, Brix, Nis, Ernst, Andreas, Henriksen, Tine Brink, Lauridsen, Lea LB, Nohr, Ellen A, Olsen, Jørn, Ramlau-Hansen, Cecilia Høst   +7 more
core   +2 more sources

Evo-devo of human adolescence: beyond disease models of early puberty [PDF]

, 2013
Despite substantial heritability in pubertal development, much variation remains to be explained, leaving room for the influence of environmental factors to adjust its phenotypic trajectory in the service of fitness goals.
A Templeton, AB Arquitt, AB Migliano, AK Pesonen, AS Parent, B Bogin, B Campbell, BH Smith, BJ Ellis, BJ Ellis, BJ Ellis, BJ Ellis, BS Zemel, C Ankarberg Lindgren, C Cooper, C Tardieu, CC Chen, CL Sisk, F Deng, GB Cutler Jr, GB Muller, GE Weisfeld, J Belsky, J Belsky, J Belsky, J Belsky, J Belsky, J Belsky, J Belsky, J Belsky, J Belsky, J Bowlby, J Bowlby, J James, J Tinggaard, Jay Belsky, JC Wingfield, JL Locke, JM Tither, KB Simondon, KK Ong, KK Ong, KO Klein, L Aksglaede, LA Proos, M Celio, M Del Giudice, M Krstevska-Konstantinova, M Mead, M Suzuki, ME Pembrey, MR Palmert, N Howell, NM Cameron, PD Gluckman, PD Kroboth, PJ Hunt, RG Westendorp, S White, SB Manuck, SC Stearns, W Arlt, W Copeland, WT Boyce, Z Hochberg, Z Hochberg, Z Hochberg, Z Hochberg, Z Hochberg, Ze'ev Hochberg   +69 more
core   +2 more sources

Homozygous mutation in the prokineticin-receptor2 gene (Val274Asp) presenting as reversible Kallmann syndrome and persistent oligozoospermia: case report. [PDF]

, 2008
Prokineticin 2 (Prok2) or prokineticin-receptor2 (Prok-R2) gene mutations are associated with Kallmann syndrome (KS). We describe a new homozygous mutation of Prok-R2 gene in a man displaying KS with an apparent reversal of hypogonadism.
Asci R, Bellastella A, Bellastella G, De Bellis A, ELEFANTE, ANDREA, Esposito D, IOLASCON, ACHILLE, Maione L, Sinisi AA   +8 more
core   +1 more source

Hypogonadotropic hypogonadism and pituitary hypoplasia as recurrent features in Ulnar-Mammary syndrome

Endocrine Connections, 2018
Ulnar-mammary syndrome (UMS) is characterized by ulnar defects, and nipple or apocrine gland hypoplasia, caused by TBX3 haploinsufficiency. Signs of hypogonadism were repeatedly reported, but the mechanisms remain elusive.
Elena Galazzi, Paolo Duminuco, Mirella Moro, Fabiana Guizzardi, Nicoletta Marazzi, Alessandro Sartorio, Sabrina Avignone, Marco Bonomi, Luca Persani, Maria Teresa Bonati   +9 more
doaj   +1 more source