Results 61 to 70 of about 465,797 (308)

Rare Complications of Cervical Spine Surgery: Pseudomeningocoele. [PDF]

, 2017
STUDY DESIGN: This study was a retrospective, multicenter cohort study. OBJECTIVES: Rare complications of cervical spine surgery are inherently difficult to investigate.
Ailon, Tamir, Arnold, Paul M., Buser, Zorica, Chou, Dean, Corriveau, Mark, Fehlings, Michael G., Fish, David E., Hilibrand, Alan S., Hsu, Wellington K., Lee, Sungho, Lord, Elizabeth L L., Massicotte, Eric M., Mroz, Thomas E., Mummaneni, Praveen V., Nassr, Ahmad, Pace, Jonathan, Riew, K. Daniel, Sasso, Rick C., Sebastian, Arjun S., Shaffrey, Christopher, Smith, Gabriel A., Smith, Justin S., Smith, Zachary A., Steinmetz, Michael P., Than, Khoi D., Traynelis, Vincent C., Wang, Jeffrey C.   +26 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Repair Integrity and Clinical Outcomes Following Arthroscopic Rotator Cuff Repair

Orthopaedic Journal of Sports Medicine, 2016
Objectives: To prospectively evaluate the effect of early versus delayed motion on repair integrity on 6-month postoperative magnetic resonance imaging (MRI) scans following rotator cuff repair, and to correlate repair integrity with clinical and ...
Ariel A. Williams MD, P. Mark Cote, RPT, Jessica Megan DiVenere BS, Stephen Austin Klinge MD, Robert A. Arciero MD, Augustus D. Mazzocca MD, MS   +5 more
doaj   +1 more source

Effect of High-Intensity Interval Training on Fatty Infiltration After Delayed Rotator Cuff Repair in a Mouse Model

Orthopaedic Journal of Sports Medicine, 2023
Background: Fatty infiltration (FI) of the rotator cuff muscles is correlated with shoulder function and retear rates after rotator cuff repair. High-intensity interval training (HIIT) induces beige adipose tissue to express more uncoupling protein 1 ...
Hecheng Zhou MD, Zili Wang MD, Chuanshun Chen MD, Hai Hu MD, Binbin Jiang MD, Yuesong Yin MD, Kexiang Zhang MD, Minren Shen MD, Song Wu MD   +8 more
doaj   +1 more source

Does Lost Time Cost You Money and Create High Risk? [PDF]

, 2012
The aim of the case study is to express the delayed repair time impact on the revenues and profit in numbers with the example of the outage of power plant units.
Fekete, István
core  

Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks. [PDF]

, 2012
Recruitment of 53BP1 to chromatin flanking double strand breaks (DSBs) requires γH2AX/MDC1/RNF8-dependent ubiquitination of chromatin and interaction of 53BP1 with histone H4 methylated on lysine 20 (H4K20me). Several histone methyltransferases have been
Guan, Yinghua, Hartlerode, Andrea J., Rajendran, Anbazhagan, Schotta, Gunnar, Scully, Ralph, Shah, Jagesh V., Ura, Kiyoe, Xie, Anyong   +7 more
core   +4 more sources

Repair Kinetics of Radiation-Induced Mitotic Delay

Biophysical Journal, 1973
The recovery from radiation-induced mitotic delay in asynchronous sarcoma-180 (S-180) ascites tumor cells has been analyzed in a manner analogous to the repair of sublethal damage. 200-R increments were separated by various fraction intervals (not exceeding the time necessary for mitosis to return to control levels) for total exposures up to 1600 R ...
Leeper, Dennis B., Hagemann, Ronald F.
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Comparison of functional outcomes following early and delayed arthroscopic repair for traumatic and non-traumatic rotator cuff injuries

Journal of Orthopaedic Surgery and Research
Background The effects of the timing of surgical repair on the outcomes of traumatic and non-traumatic rotator cuff injuries (RCI) remain elusive.
Aixin Liu, Baorui Zhang, Tong Lai, Mingxing Wang, Gongyi Wu, Shilin Liu, Tao Zhang   +6 more
doaj   +1 more source