Results 81 to 90 of about 741,169 (252)

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

Advanced Science, EarlyView.
This review summarizes the pathogenic role of mitochondria in diseases and highlights mitochondrial transfer and transplantation as emerging therapeutic strategies. It systematically discusses how nanomaterials are engineered to facilitate these processes, and critically examines the current challenges and future perspectives for their clinical ...
Yuanyuan Su, Zhiyan Gong, Jiao Mu, Lili Huang, Pengfei Yang, Chenli Zhang, Lingshan Zhao, Liling Yang, Jun Deng, Xiaohui Liao   +9 more
wiley   +1 more source

Spontaneous (atraumatic) splenic rupture complicating anticoagulant treatment for splenic infarction.

, 2013
We report the case of a 61-year-old male patient who suffered a spontaneous (atraumatic) splenic rupture (SSR) following splenic infarction treated by heparin anticoagulation. Splenic rupture precipitated by thrombolytic or anticoagulant therapy has been
Colin, Geoffrey, Philippe Hainaut, Fabrice C. Deprez, Deprez, Fabrice, Hainaut, Philippe, Geoffrey C. Colin   +5 more
core   +1 more source

Spontaneous splenic rupture in pregnancy [PDF]

, 2016
Splenic rupture during pregnancy is a rare and can frequently be a misdiagnosed pathology. This rupture is associated with a high maternal and fetal mortality rate.
Khabouz, S, Mohamed, J, Benkirane, S, Khabouz, Samira, Masrar, Azlarab, Mukendi, J.N., Elghanmi, A, Mohamed, Jou, Elghanmi, Adil, Masrar, A, Mukendi, Jean-Louis Ntumba, Benkirane, Souad   +11 more
core   +1 more source

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

Advanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou, Lei Zhang, Xingyu Cai, Jiajia Su, Guangyu Dai, Xue Chen, Hanming Wang, Jia Hua, Jianping Liu, Chunmeng Sun, Xiancheng Chen, Erhao Wang, Wenli Zhang   +12 more
wiley   +1 more source

Fatal Recurrent Splenic Artery Pseudoaneurysm Rupture Despite Prior Successful Embolization in Alcohol-Associated Chronic Pancreatitis: A Case Report

Reports
Background and Clinical Significance: Splenic artery pseudoaneurysm (SAP) is a rare but life-threatening complication of chronic pancreatitis. Although endovascular embolization achieves high technical success, recurrence and delayed rupture may occur ...
Nawras Ibrahim, Stéphanie Ammari, Faiza Malik   +2 more
doaj   +1 more source

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

Advanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun, Ruiqi Wu, Qingshuang Tang, Yunli Xu, Wanrui Shi, Mengxin Wang, Haonan Wang, Yan Luo, Cheng Ma, Xiaolong Liang   +9 more
wiley   +1 more source

Spontaneous rupture of spleen in the second trimester: a case report and literature review

BMC Pregnancy and Childbirth
Background Spontaneous rupture of the spleen during pregnancy or after delivery is an extremely rare, potentially life-threatening complication that poses major diagnostic and therapeutic challenges.
Yilin Meng, Xuan Zhang
doaj   +1 more source

Atraumatic splenic rupture associated with apixaban [PDF]

, 2019
Apixaban is a direct oral anticoagulant that works by inhibiting factor Xa. It has been associated with adverse bleeding outcomes including atraumatic splenic rupture.
Mir, Izza, Koirala, Ajay, Elan Mohanty, Ajay Koirala, Niranjan Tachamo, Mohanty, Elan, Dhital, Rashmi, Sijan Basnet, Tachamo, Niranjan, Izza Mir, Rashmi Dhital, Basnet, Sijan   +11 more
core   +1 more source

Closing the Loop: High‐Precision 3D Photofabrication in Living Tissues

Advanced Science, EarlyView.
Writing 3D microstructures inside living tissue demands more than laser access; It demands information. Hierarchical sensing captures thermal and mechanical states across pulse‐train, voxel, and structure timescales, feeding a controller that steers the laser in real time.
Amirbahador Zeynali, Mangirdas Malinauskas, Giuseppe Chirico   +2 more
wiley   +1 more source

Case Report: Disseminated actinomycosis-induced splenic rupture with spleen and liver abscesses

Frontiers in Medicine
Disseminated actinomycosis is a rare, slowly progressing infection caused by Actinomyces species and can manifest as the formation of multiple abscesses and sulfur granules in infected tissues.
Huaijuan Li, Zhaoping Cheng, Kui Li
doaj   +1 more source