Results 21 to 30 of about 1,717,353 (273)

Detection of a Cryptic 25 bp Deletion and a 269 Kb Microduplication by Nanopore Sequencing in a Seemingly Balanced Translocation Involving the LMLN and LOC105378102 Genes

Frontiers in Genetics, 2022
Preimplantation genetic testing plays a critical role in enabling a balanced translocation carrier to obtain the normal embryo. Identifying the precise breakpoints for the carriers with phenotypic abnormity, allows us to reveal disrupted genes.
Yanan Wang, Zhenhua Zhao, Xinyu Fu, Shufang Li, Qiuyan Zhang, Xiangdong Kong   +5 more
doaj   +1 more source

Dynamic Graphs on the GPU [PDF]

, 2020
We present a fast dynamic graph data structure for the GPU. Our dynamic graph structure uses one hash table per vertex to store adjacency lists and achieves 3.4–14.8x faster insertion rates over the state of the art across a diverse set of large datasets,
Ashkiani, Saman, Awad, Muhammad A., Owens, John D., Porumbescu, Serban D.   +3 more
core   +1 more source

Deletions of the derivative chromosome 9 occur at the time of the Philadelphia translocation and provide a powerful and independent prognostic indicator in chronic myeloid leukemia [PDF]

, 2001
Chronic myeloid leukemia (CML) is characterized by formation of the BCR-ABL fusion gene, usually as a consequence of the Philadelphia (Ph) translocation between chromosomes 9 and 22.
Bench, AJ, Campbell, LJ, Grace, C, Green, AR, Huntly, BJP, Nacheva, EP, Prince, HM, Reid, AG, Shepherd, P, Szer, J, Telford, N, Turner, P   +11 more
core   +1 more source

Central 22q11.2 deletions

American Journal of Medical Genetics Part A, 2014
22q11.2 deletion syndrome is one of the most common microdeletion syndromes. Most patients have a deletion resulting from a recombination of low copy repeat blocks LCR22‐A and LCR22‐D. Loss of the TBX1 gene is considered the most important cause of the phenotype.
Rump, P., Leeuw, N. de, Essen, A.J. van, Verschuuren-Bemelmans, C.C., Veenstra-Knol, H.E., Swinkels, M.E.M., Oostdijk, W., Ruivenkamp, C., Reardon, W., Munnik, S. de, Ruiter, M., Frumkin, A., Lev, D., Evers, C., Sikkema-Raddatz, B., Dijkhuizen, T., Ravenswaaij-Arts, C.M. van   +16 more
openaire   +4 more sources

Genomic analysis of storage protein deficiency in common bean (Phaseolus vulgaris)

Frontiers in Plant Science, 2016
A series of genetically related lines of common bean (Phaseolus vulgaris L.) integrate a progressive deficiency in major storage proteins, the 7S globulin phaseolin and lectins.
Sudhakar ePandurangan, Sudhakar ePandurangan, Marwan eDiapari, Fuqiang eYin, Fuqiang eYin, Seth eMunholland, Gregory E. Perry, Patrick eChapman, Shangzhi eHuang, Francesca eSparvoli, Roberto eBollini, William Leonard Crosby, Karl Peter Pauls, Frédéric eMarsolais, Frédéric eMarsolais   +14 more
doaj   +1 more source

From karyotypes to precision genomics in 9p deletion and duplication syndromes

HGG Advances, 2022
While 9p deletion and duplication syndromes have been studied for several years, small sample sizes and minimal high-resolution data have limited a comprehensive delineation of genotypic and phenotypic characteristics.
Eleanor I. Sams, Jeffrey K. Ng, Victoria Tate, Ying-Chen Claire Hou, Yang Cao, Lucinda Antonacci-Fulton, Khadija Belhassan, Julie Neidich, Robi D. Mitra, F. Sessions Cole, Patricia Dickson, Jeffrey Milbrandt, Tychele N. Turner   +12 more
doaj   +1 more source

Parameterized lower bound and NP-completeness of some $H$-free Edge Deletion problems [PDF]

, 2015
For a graph $H$, the $H$-free Edge Deletion problem asks whether there exist at most $k$ edges whose deletion from the input graph $G$ results in a graph without any induced copy of $H$.
C Komusiewicz, DB West, ES El-Mallah, HL Bodlaender, JM Lewis, L Cai, M Cygan, M Yannakakis, MR Fellows, N Bansal, PG Drange, PW Goldberg   +11 more
core   +2 more sources

Antecedent-Contained Deletion as Deletion

Linguistics in the Netherlands, 1999
Recent discussion of the phenomenon of Antecedent-Contained Deletion (ACD, illustrated in (1)) continues to assume that the basic problem to be accounted for is one of infinite regress under LF-reconstruction of the antecedent VP (VP1) in the position of the empty VP (VP2) (e.g.
Guido Vanden Wyngaerd, C. Jan-Wouter Zwart   +1 more
openaire   +2 more sources

A U508C synonymous mutation in the SARS-CoV-2 deletion hotspot reduces deletion frequency and accelerates viral clearance

mBio
A deletion hotspot within the non-structural protein 1 (NSP1) gene (locus 500–532) has been observed in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes analyzed by next-generation sequencing.
Kaya Miyazaki, Akihiro Doi, Yuriko Tomita, Wataru Kamitani, Shutoku Matsuyama   +4 more
doaj   +1 more source

Isolation and Identification of Subgroup J Avian Leukosis Virus Inducing Multiple Systemic Tumors in Parental Meat-Type Chickens

Frontiers in Veterinary Science, 2021
Avian leukosis virus (ALV) continues evolving to obtain new genomic characters to enhance its pathogenicity. In the present study, an ALV-J strain LH20180301 was isolated from broiler breeder chickens that reached the speak of paralyzation before 20-week-
Ning Cui, Xuezhi Cui, Qinghua Huang, Shaohua Yang, Shuai Su, Chuantian Xu, Jianhe Li, Wenfeng Li, Chao Li   +8 more
doaj   +1 more source