Results 41 to 50 of about 1,717,353 (273)

A naturally occurring NS1 variant with effector domain deletion gains growth advantages in influenza virus infection

Emerging Microbes and Infections
High pathogenicity avian influenza virus (HPAIV) poses major threats to both poultry health and public safety. The viral nonstructural protein 1 (NS1) plays a crucial role in counteracting innate immunity.
Ruei-Sheng Tsai, Jun-Yuh Tsai, Yun-Ting Chung, Ching-Yu Tseng, Guan-Ru Liao, Randy A. Albrecht, Chih-Ying Kuan, Rei-Lin Kuo, Shan-Chia Ou, Wei-Li Hsu   +9 more
doaj   +1 more source

Accurate detection of α-globin gene copy number variants with two reactions using droplet digital PCR

Hematology, 2022
Background The α-thalassemia is a highly prevalent disease in tropical and subtropical regions, including southern China, and is mainly caused by deletion in α-globin genes (HBA1 and HBA2). The clinical manifestation of α-thalassemia is highly correlated
Xiuqin Bao, Danqing Qin, Jian Ma, Xiangcheng Zhou, Jicheng Wang, Cuize Yao, Liang Zhang, Li Du   +7 more
doaj   +1 more source

Deletion-restriction in toric arrangements [PDF]

, 2015
Deletion-restriction is a fundamental tool in the theory of hyperplane arrangements. Various important results in this field have been proved using deletion-restriction.
Deshpande, Priyavrat, Sutar, Kavita
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The CST complex mediates a post-resection non-homologous end joining repair pathway and promotes local deletions in Saccharomyces cerevisiae

Cell Genomics
Summary: The repair of a DNA double-strand break (DSB) by non-homologous end joining (NHEJ) generally leaves an intact or minimally modified sequence. Resection exposes single-stranded DNA and directs repair toward homology-dependent pathways and away ...
Oana Ilioaia, Liébaut Dudragne, Clémentine Brocas, Léa Meneu, Romain Koszul, Karine Dubrana, Zhou Xu   +6 more
doaj   +1 more source

Meiotic Chromosomal Abnormality Detected in a Heterozygote of Elymus nutans

Frontiers in Plant Science, 2022
Elymus nutans is an allopolyploid with a genome constitution of StStYYHH (2n = 6x = 42). Highly frequent intergenomic translocations and chromosomal variations with repeat amplification and deletions in E.
Bo Liu, Bo Liu, Xiaoyan Tao, Xiaoyan Tao, Quanwen Dou, Quanwen Dou   +5 more
doaj   +1 more source

A Note on the Deletion Channel Capacity [PDF]

, 2012
Memoryless channels with deletion errors as defined by a stochastic channel matrix allowing for bit drop outs are considered in which transmitted bits are either independently deleted with probability $d$ or unchanged with probability $1-d$.
Duman, Tolga M., Rahmati, Mojtaba
core  

Preferential survival in models of complex ad hoc networks

, 2007
There has been a rich interplay in recent years between (i) empirical investigations of real world dynamic networks, (ii) analytical modeling of the microscopic mechanisms that drive the emergence of such networks, and (iii) harnessing of these ...
Adamic, Adamic, Albert, Barabasi, Bianconi, Borgs, Bornholdt, Chawathe, Chen, Cho, Chung, Cooper, Deng, Dorogovtsev, Geng, Gomes, Gulli, Huberman, Jeong, Joseph S. Kong, Kleinberg, Krapivsky, Kumar, Moore, Motwani, Newman, Pennock, Sarshar, Sarshar, Sarshar, Simon, Vwani P. Roychowdhury, Vázquez, Willis, Wouhaybi   +34 more
core   +1 more source

A multi-exon deletion within WWOX is associated with a 46,XY disorder of sex development [PDF]

, 2011
Disorders of sex development (DSD) are congenital conditions where chromosomal, gonad or genital development is atypical. In a significant proportion of 46,XY DSD cases it is not possible to identify a causative mutation, making genetic counseling ...
AJ Notini, AJ Paige, AK Bednarek, Andrew Sinclair, D Wilhelm, DM Maatouk, E Sutton, Erin Turbitt, H Stoop, Jacqueline Hewitt, JH Ludes-Meyers, Leendert Looijenga, LH Looijenga, M Cools, M Cools, Martine Cools, MI Nunez, N Bouteille, PA Lee, Peter Koopman, R Hersmus, Remko Hersmus, RI Aqeilan, RI Aqeilan, RI Aqeilan, RI Aqeilan, S Del Mare, SJ White, SJ White, Stefan White, Stenvert Drop, Vincent Harley, Yvonne van der Zwan   +32 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source