Results 41 to 50 of about 1,098,495 (316)

Genome- and transcriptome-assisted development of nuclear insertion/deletion markers for Calanus species (Copepoda: Calanoida) identification [PDF]

, 2014
Copepods of the genus Calanus are key zooplankton species in temperate to arctic marine ecosystems. Despite their ecological importance, species identification remains challenging.
Poortvliet, Marloes, Hoarau, Galice, Smolina, Irina, Smolina, I, Kollias, Spyros, Castellani, Claudia, Kollias, S., Blanco-Bercial, L., Nielsen, Torkel Gissel, Hoarau, Galice Guillaume, Castellani, C, Poortvliet, M, Kollias, S, Møller, Eva, Poortvliet, M., Lindeque, PK, Hoarau, G., Lindeque, Penelope, Castellani, C., Nielsen, TG, Hoarau, G, Blanco-Bercial, Leocadio, Møller, E.F., Lindeque, P., Smolina, I., Møller, EF, Møller, Eva Friis, Møller, E. F., Blanco-Bercial, L, Nielsen, Torkel   +29 more
core   +1 more source

Characteristics of four natural poliovirus type 1 variants with six-nucleotide deletion (2,783–2,788 nt) in the VP1 region

Microbiology Spectrum
Since the establishment of the Chinese acute flaccid paralysis (AFP) case surveillance system in 1999, around 7,200 strains of poliovirus (PV) type 1 have been identified and isolated.
Jie Lin, Lei Zhou, Chenglin Zhu, Jinhang Wei, Bo Lv, Yuan Si, Shuangli Zhu, Tianjiao Ji, Dongyan Wang, Qian Yang, Jinbo Xiao, Lan Yang, Kaitao Xiao, Kexin Shao, Yong Zhang, Dongmei Yan   +15 more
doaj   +1 more source

Detection of a Cryptic 25 bp Deletion and a 269 Kb Microduplication by Nanopore Sequencing in a Seemingly Balanced Translocation Involving the LMLN and LOC105378102 Genes

Frontiers in Genetics, 2022
Preimplantation genetic testing plays a critical role in enabling a balanced translocation carrier to obtain the normal embryo. Identifying the precise breakpoints for the carriers with phenotypic abnormity, allows us to reveal disrupted genes.
Yanan Wang, Zhenhua Zhao, Xinyu Fu, Shufang Li, Qiuyan Zhang, Xiangdong Kong   +5 more
doaj   +1 more source

From karyotypes to precision genomics in 9p deletion and duplication syndromes

HGG Advances, 2022
While 9p deletion and duplication syndromes have been studied for several years, small sample sizes and minimal high-resolution data have limited a comprehensive delineation of genotypic and phenotypic characteristics.
Eleanor I. Sams, Jeffrey K. Ng, Victoria Tate, Ying-Chen Claire Hou, Yang Cao, Lucinda Antonacci-Fulton, Khadija Belhassan, Julie Neidich, Robi D. Mitra, F. Sessions Cole, Patricia Dickson, Jeffrey Milbrandt, Tychele N. Turner   +12 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery [PDF]

, 2014
Background:Wider clinical applications of 9p status in clear cell renal cell carcinoma (ccRCC) are limited owing to the lack of validation and consensus for interphase fluorescent in situ hybridisation (I-FISH) scoring technique.
Fleming, S., P Rauchhaus, J Fitzpatrick, Fitzpatrick, J., N Pratt, S Fleming, J Bondad, J Cunningham, El-Mokadem, I., Cunningham, J., Bondad, J., Nabi, G., Rauchhaus, P., G Nabi, Pratt, N., I El-Mokadem   +15 more
core   +1 more source

Isolation and Identification of Subgroup J Avian Leukosis Virus Inducing Multiple Systemic Tumors in Parental Meat-Type Chickens

Frontiers in Veterinary Science, 2021
Avian leukosis virus (ALV) continues evolving to obtain new genomic characters to enhance its pathogenicity. In the present study, an ALV-J strain LH20180301 was isolated from broiler breeder chickens that reached the speak of paralyzation before 20-week-
Ning Cui, Xuezhi Cui, Qinghua Huang, Shaohua Yang, Shuai Su, Chuantian Xu, Jianhe Li, Wenfeng Li, Chao Li   +8 more
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Independent regulation of P53 stabilisation and activation after Rb deletion in primary epithelial cells [PDF]

, 2010
We have previously reported that deletion of the retinoblastoma gene Rb leads to rapid but transient p53 stabilisation. We investigated here the pathways involved.
Bellamy, Christopher, Harrison, David J, Treanor, Louise, Prost, Sandrine, Harrison, David J.   +4 more
core   +1 more source

A naturally occurring NS1 variant with effector domain deletion gains growth advantages in influenza virus infection

Emerging Microbes and Infections
High pathogenicity avian influenza virus (HPAIV) poses major threats to both poultry health and public safety. The viral nonstructural protein 1 (NS1) plays a crucial role in counteracting innate immunity.
Ruei-Sheng Tsai, Jun-Yuh Tsai, Yun-Ting Chung, Ching-Yu Tseng, Guan-Ru Liao, Randy A. Albrecht, Chih-Ying Kuan, Rei-Lin Kuo, Shan-Chia Ou, Wei-Li Hsu   +9 more
doaj   +1 more source