Results 51 to 60 of about 1,174,028 (302)

Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery [PDF]

, 2014
Background:Wider clinical applications of 9p status in clear cell renal cell carcinoma (ccRCC) are limited owing to the lack of validation and consensus for interphase fluorescent in situ hybridisation (I-FISH) scoring technique.
Fleming, S., P Rauchhaus, J Fitzpatrick, Fitzpatrick, J., N Pratt, S Fleming, J Bondad, J Cunningham, El-Mokadem, I., Cunningham, J., Bondad, J., Nabi, G., Rauchhaus, P., G Nabi, Pratt, N., I El-Mokadem   +15 more
core   +1 more source

The CST complex mediates a post-resection non-homologous end joining repair pathway and promotes local deletions in Saccharomyces cerevisiae

Cell Genomics
Summary: The repair of a DNA double-strand break (DSB) by non-homologous end joining (NHEJ) generally leaves an intact or minimally modified sequence. Resection exposes single-stranded DNA and directs repair toward homology-dependent pathways and away ...
Oana Ilioaia, Liébaut Dudragne, Clémentine Brocas, Léa Meneu, Romain Koszul, Karine Dubrana, Zhou Xu   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Independent regulation of P53 stabilisation and activation after Rb deletion in primary epithelial cells [PDF]

, 2010
We have previously reported that deletion of the retinoblastoma gene Rb leads to rapid but transient p53 stabilisation. We investigated here the pathways involved.
Bellamy, Christopher, Harrison, David J, Treanor, Louise, Prost, Sandrine, Harrison, David J.   +4 more
core   +1 more source

Temporal Tampering Detection in Automotive Dashcam Videos via Multi-Feature Forensic Analysis and a 1D Convolutional Neural Network

Sensors
Automotive dashboard cameras are widely used to record driving events and often serve as critical evidence in accident investigations and insurance claims.
Ali Rehman Shinwari, Uswah Binti Khairuddin, Mohamad Fadzli Bin Haniff   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Proximal 4p Deletion Syndrome in an Infant With Multiple Systemic Anomalies

Molecular Genetics & Genomic Medicine
Background Contiguous gene deletion in the short arm of chromosome 4 is linked to various neurodevelopmental disorders. Methods In this study, we conducted peripheral blood chromosome G‐banding karyotyping and whole‐exome sequencing (WES) on a proband ...
Ying Pang, Lan Zeng, Hua Liang, Chunlan Cheng, Lihui Shan, Jin Wang, Nanjing Jiang, Guanghuan Pi, Li Yang, Ai Chen, Fu Xiong, Shuyao Zhu   +11 more
doaj   +1 more source

Identification of Two Porcine Reproductive and Respiratory Syndrome Virus Variants Sharing High Genomic Homology but with Distinct Virulence

Viruses, 2019
Porcine reproductive and respiratory syndrome virus (PRRSV) causes huge economic loss to the global swine industry. Even though several control strategies have been applied, PRRS is still not effectively controlled due to the continuous emergence of new ...
Nanhua Chen, Mengxue Ye, Yucheng Huang, Shuai Li, Yanzhao Xiao, Xinshuai Li, Shubin Li, Xiangdong Li, Xiuling Yu, Kegong Tian, Jianzhong Zhu   +10 more
doaj   +1 more source

Influence of False Self-Presentation on Mental Health and Deleting Behavior on Instagram: The Mediating Role of Perceived Popularity

Frontiers in Psychology, 2021
The present study explored motivations (need for approval, impression management) for lying self-presentation on Instagram as well as the mental and behavioral outcomes (depression, perceived popularity, deleting behavior on Instagram) of this ...
Il Bong Mun, Hun Kim
doaj   +1 more source

Antecedent-Contained Deletion as Deletion

Linguistics in the Netherlands, 1999
Recent discussion of the phenomenon of Antecedent-Contained Deletion (ACD, illustrated in (1)) continues to assume that the basic problem to be accounted for is one of infinite regress under LF-reconstruction of the antecedent VP (VP1) in the position of the empty VP (VP2) (e.g.
Guido Vanden Wyngaerd, C. Jan-Wouter Zwart   +1 more
openaire   +2 more sources