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DELIBERATIONDeliberative democratic theory is a normative, talk-centric democratic theory where deliberation and deliberative debate and discussion take center stage. For a political discussion to be deliberative, it should meet certain communicative standards.
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Sustaining Public Engagement: Embedded Deliberation in Local Communities [PDF]
, 2009 Describes nine communities using organized deliberation to consider public issues over several years and their accomplishments and analyzes how public deliberation addresses deficits in local democratic governance.
Archon Fung, Elena Fagotto
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
A Reply to John Dudley on Aristotle, Physics 2.5, 196b17–21
Peitho, 2017 In this article, I restate the interpretation of Aristotle’s Ph. 2.5, 196b17– 21, which I presented for the first time in my book I fondamenti della causalità naturale (2006).
Giovanna R. Giardina
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
, 2011 “Deliberative democracy” refers to democratic processes based on thorough consideration and discussion of issues from a variety of perspectives. Although voting and other ways of tallying opinions are often part of deliberation, it seeks to go beyond the mere aggregation of preferences through processes of collective discussion.
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Media and Communication, 2019 Deliberation research is now undergoing two emerging trends: deliberation is shifting from offline to online, as well as from an inherently democratic concept to the one applicable to less competitive regimes (He & Warren, 2011). The goal of this article
Olga Filatova +2 more
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NACCS 41st Annual Conference [PDF]
, 2014 Fragmented Landscapes in Chicana and Chicano Studies: Deliberation, Innovation or Extinction?April 9-12, 2014Hilton Salt Lake City Centerhttps://scholarworks.sjsu.edu/naccs_programs/1031/thumbnail ...
National Association for Chicana and Chicano Studies
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A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
What Happened on Deliberation Day? [PDF]
What are the effects of deliberation about political issues? This essay reports the results of a kind of Deliberation Day, involving sixty-three citizens in Colorado.
Hastie, Reid +2 more
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