Results 41 to 50 of about 195,918 (308)

Dose⁃response relationship between delirium duration and post⁃intensive care syndrome⁃cognitive impairment

Huli yanjiu, 2023
ObjectiveTo explore the dose⁃response relationship between delirium duration and post⁃intensive care syndrome⁃cognitive impairment（PICS⁃CI）.MethodsA total of 271 critically ill patients from two tertiary grade A comprehensive hospitals in Fujian province
WEI Yueqing, WU Tingting, YI Bilan, LI Hong   +3 more
doaj  

In-hospital delirium risk assessment, diagnosis and management; medications to avoid

Italian Journal of Medicine, 2013
Background: Delirium is a common, but potentially preventable complication of acute illness that is associated with important adverse outcomes including increased length of hospital admission, risk of dementia and admission to long-term care. In-hospital
Andrew Clegg, John Young
doaj   +1 more source

Delirium Tremens [PDF]

Medical Journal Armed Forces India, 2004
The varied clinical manifestations and management of 14 male patients with delirium tremens (DT) have been studied. Eight patients were initially hospitalised for diseases unrelated to ethanol abuse i.e. 2 each for gun shot wound, myocardial infarction and stroke, and one each for pneumonia and gastroenteritis.
S R, Mehta, Hra, Prabhu, A J, Swamy, Harinder, Dhaliwal, Dinesh, Prasad   +4 more
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Modulating delirium through stimulation (MoDeSt): study protocol for a randomized, double-blind, sham-controlled trial assessing the effect of postoperative transcranial electrical stimulation on delirium incidence

Trials
Background Postoperative delirium (POD) is the most common neurological adverse event among elderly patients undergoing surgery. POD is associated with an increased risk for postoperative complications, long-term cognitive decline, an increase in ...
Sophie Leroy, Viktor Bublitz, Ulrike Grittner, Robert Fleischmann, Falk von Dincklage, Daria Antonenko   +5 more
doaj   +1 more source

Geriatric Delirium Care: Using Chart Audits to Target Improvement Strategies

Canadian Geriatrics Journal, 2017
Background Our hospital identified delirium care as a quality improvement target. Baseline characterization of our delirium care and deficits was needed to guide improvement efforts.
Carla A. Loftus, Lesley A. Wiesenfeld
doaj   +1 more source

Delirium education for geriatric patients and their families: A quality improvement initiative✰

Aging and Health Research, 2023
Delirium affects up to 50% of hospitalized older adults, contributing to poor outcomes. Family members can be engaged in delirium identification, prevention, and management.
Serena P. Wong, Jennifer Tu, Stuart Downie, Mitchell T. Heflin, Shelley R. McDonald, Mamata Yanamadala   +5 more
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Neurogranin in cerebrospinal fluid as a marker of synaptic dysfunction in hip fracture patients with delirium: a multicentre cross-sectional study

BMJ Open
Objectives Neurogranin (Ng) has a role in synaptic plasticity and is considered a biomarker of synaptic dysfunction, a process hypothesised to be important in delirium. Few studies examining Ng in delirium exist, with mixed findings.
Henrik Zetterberg, Kaj Blennow, Dag Aarsland, Marius Myrstad, Mathias N P Hella, Nathalie B Halaas, Hogne Soennesyn, Anne K Bergland, Hanne B Hetland, Audun O Vik-Mo, Ane-Victoria Idland, Christian T Pollmann, Bjørn E Neerland, Leiv O Watne   +13 more
doaj   +1 more source

Risk Factors and Outcomes for Postoperative Delirium after Major Surgery in Elderly Patients. [PDF]

PLoS ONE, 2015
Early identification of patients at risk for delirium is important, since adequate well timed interventions could prevent occurrence of delirium and related detrimental outcomes.
Jelle W Raats, Wilbert A van Eijsden, Rogier M P H Crolla, Ewout W Steyerberg, Lijckle van der Laan   +4 more
doaj   +1 more source