Results 91 to 100 of about 2,685,673 (317)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Peptide and protein delivery /
, 2011 The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. A needed reference for entry level researchers and researchers working in interdisciplinary / collaborative projects, Peptide
Van der Walle, Chris.
core
zelepukiny/FlaRE-delivery: FlaRE Delivery
, 2022 Code used for theoretical modelling of drug delivery into the tissue via free drug and encapsulated drug with different release ...
zelepukiny
core +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Evaluation of an Internet Document Delivery Service [PDF]
, 2001 An Internet-based Document Delivery Service (DDS) has been developed within the framework of the CNR ( the Italian Research National Council) Project BiblioMIME, in order to take advantage of new Internet technologies and promote cooperation among ...
Mangiaracina, Silvana +9 more
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Maternal and perinatal outcomes of live births after uterus transplantation: A systematic review
Acta Obstetricia et Gynecologica ScandinavicaIntroduction Uterus transplantation (UTx) is a treatment for absolute uterine factor infertility. The results of pregnancies of this complex infertility treatment should be established.
Mats Brännström +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Service delivery review: a how to manual for local government [PDF]
, 2014 This resource aims to assist councils assess the services they provide for local communities. Service Delivery Review: A How to Manual for Local Government brings together advice, toolkits and templates to help councils regardless of size ...
Roberta Ryan +5 more
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THE OBSTETRIC TACTICS IN ACUTE APPENDICITIS IN PREGNANCY
Акушерство, гинекология и репродукция, 2016 The results of tocolytic therapy for prolongation pregnancy and delivery in pregnant women with severe appendicitis 45. In the structure of the women operated on appendicitis pregnant amounted to 5.7%.
A. G. Khasanov +5 more
doaj