Results 91 to 100 of about 812,479 (302)

Integration of health care delivery in the Eastern Mediterranean Region of the World Health Organization

Eastern Mediterranean Health Journal, 2000
This paper reviews developments in the integration of health care delivery in the Eastern Mediterranean Region. It describes the integrated intersectoral support of socioeconomic community development [district health systems and basic development needs], the functional intrasectoral integration of health services and interventions, and health ...
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Is the content of guidelines/pathways a barrier for the integration of palliative Care in Chronic Heart Failure (CHF) and chronic pulmonary obstructive disease (COPD)? A comparison with the case of cancer in Europe

BMC Palliative Care, 2017
Background There is a notable inequity in access to palliative care (PC) services between cancer and Chronic Heart Failure (CHF)/Chronic Obstructive Pulmonary Disease (COPD) patients which also translates into discrepancies in the level of integration of
Naouma Siouta, Karen Van Beek, Sheila Payne, Lukas Radbruch, Nancy Preston, Jeroen Hasselaar, Carlos Centeno, Johan Menten   +7 more
doaj   +1 more source

Integrated care: What strategies and other arrangements support and influence integration at the meso/organisational level? [PDF]

, 2013
Historically, general practice has been the principal access point for health care delivery in the Australian community. Alongside the growing trend in specialised care, there has been increased fragmentation of health care services, particularly for ...
Brown, Lynsey, Bywood, Petra Teresia, Oliver-Baxter, Jodie   +2 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Divergent modes of integration: the Canadian way

International Journal of Integrated Care, 2011
Introduction: The paper highlights key trajectories and outcomes of the recent policy developments toward integrated health care delivery systems in Quebec and Ontario in the primary care sector and in the development of regional networks of health and ...
Izzat Jiwani, Marie-Josée Fleury
doaj   +3 more sources

Strengthening the delivery of integrated care for individuals experiencing serious mental illness within mental health settings: a qualitative description of health provider perspectives

BMC Psychiatry
Background Individuals experiencing serious mental illness (SMI) have higher rates of comorbid physical health conditions, poorer associated health outcomes, and die on average 10–20 years earlier than the general population.
Munazzah Ambreen, Christopher Canning, Brian Lo, Sri Mahavir Agarwal, Amer M. Burhan, David Castle, M. Elisabeth Del Giudice, Barna Konkolÿ-Thege, Louis Liu, Osnat C. Melamed, Frank Sirotich, Sanjeev Sockalingam, Gillian Strudwick, Tania Tajirian, Philip G. Tibbo, Mary Rose van Kesteren, Caroline Walker, Vicky Stergiopoulos   +17 more
doaj   +1 more source

Basic newborn care and neonatal resuscitation: a multi-country analysis of health system bottlenecks and potential solutions. [PDF]

, 2015
BACKGROUND: An estimated two-thirds of the world's 2.7 million newborn deaths could be prevented with quality care at birth and during the postnatal period.
Bégin, France, Dickson, Kim E, Enweronu-Laryea, Christabel, Lawn, Joy E, Lee, Anne CC, Moxon, Sarah G, Niermeyer, Susan, Nyange, Christabel, Simen-Kapeu, Aline, Sobel, Howard L, von Xylander, Severin   +10 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Collaboration, coordination and communication as facilitators of transitions for patients with advanced cancer: a scoping review linked to the Pal-Cycles project

BMC Palliative Care
Background Person-centred care is becoming increasingly recognised as an important element of palliative care. The current review syntheses evidence in relation to transitions in advanced cancer patients with palliative care needs.
Rachel Louise Hooley, Sheila Payne, Dunja Begovic, Juan Esteban Correa-Morales, Andrew Harding, Jeroen Hasselaar, Nancy Preston   +6 more
doaj   +1 more source