Results 111 to 120 of about 2,178,752 (317)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Staff Experiences Transitioning to Digital Dermatopathology in a Tertiary Academic Medical Center: Lessons Learned From Implementation Science

Mayo Clinic Proceedings: Digital Health
Digital pathology (DP) transforms practice by replacing traditional glass slide review with digital whole slide images and workflows. Although digitization may improve accuracy and efficiency, transitioning to digital practice requires staff to learn new
Celia C. Kamath, PhD, Erin O. Wissler Gerdes, MA, Barbara A. Barry, PhD, Sarah A. Minteer, PhD, Nneka I. Comfere, MD, Margot S. Peters, MD, Carilyn N. Wieland, MD, Elizabeth B. Habermann, PhD, Jennifer L. Ridgeway, PhD   +8 more
doaj   +1 more source

Poverty and access to maternal health care in Tajikistan

, 2003
Using recently available survey data for Tajikistan, this paper investigates changes in the pattern of maternal health care over the last decade, and the extent to which inequalities in access to that care have emerged.
Falkingham, Jane
core  

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

The role of telemedicine in the delivery of health care in the COVID-19 pandemic. [PDF]

Haemophilia, 2020
Valentino LA, Skinner MW, Pipe SW.
europepmc   +1 more source

Designing a New Model for Clinical Education: An Innovative Approach. [PDF]

, 2017
To keep pace with the ever-changing health care delivery system, it is important to transform the way future nurses are educated, both in classroom and in clinical settings, to care for people along the life and care continuum, not only in acute-care ...
Bouchaud, Mary, Shaffer, Kathryn, Swan, Beth Ann   +2 more
core   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Depression and Anxiety Among Patients on Chronic Opioid Therapy

Health Services Research & Managerial Epidemiology, 2018
Background: Chronic noncancer pain (CNCP) and chronic opioid therapy (COT) commonly coexist with comorbid depression and anxiety. We investigated the prevalence of depression and anxiety and their correlates at the time of controlled substance agreement (
Muhamad Y. Elrashidi, Lindsey M. Philpot, Priya Ramar, William B. Leasure, Jon O. Ebbert   +4 more
doaj   +1 more source

Optimizing the stake holder’s perspective on enhancing the service quality in health care [PDF]

For the success of health care organizations, accurate measurement of health care service quality is as important as understanding the nature of the service delivery system.
G, Thiagarajan, Nakkeeran, Senthil kumar
core   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source