Results 101 to 110 of about 177,396,190 (300)

Staff Experiences Transitioning to Digital Dermatopathology in a Tertiary Academic Medical Center: Lessons Learned From Implementation Science

Mayo Clinic Proceedings: Digital Health
Digital pathology (DP) transforms practice by replacing traditional glass slide review with digital whole slide images and workflows. Although digitization may improve accuracy and efficiency, transitioning to digital practice requires staff to learn new
Celia C. Kamath, PhD, Erin O. Wissler Gerdes, MA, Barbara A. Barry, PhD, Sarah A. Minteer, PhD, Nneka I. Comfere, MD, Margot S. Peters, MD, Carilyn N. Wieland, MD, Elizabeth B. Habermann, PhD, Jennifer L. Ridgeway, PhD   +8 more
doaj   +1 more source

Unfair inequalities in health and health care [PDF]

Inequalities in health and health care are caused by different factors. Measuring "unfair"inequalities implies that a distinction is introduced between causal variables leading toethically legitimate inequalities and causal variables leading to ethically
FLEURBAEY, Marc, SCHOKKAERT, Erik
core  

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Identification of Patients for a Community Health Worker Program Using an Artificial Intelligence Algorithm

Learning Health Systems
Introduction Community health workers (CHWs) help patients navigate community resources. CHW programs can improve health outcomes and reduce healthcare utilization, but identifying eligible patients is challenging.
Samuel T. Savitz, Brendan Broderick, Margaret M. Paul, Timethia J. Bonner, Jennifer L. Ridgeway, Mikaela Kall, Jane W. Njeru   +6 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Identifying factors influencing emerging innovations in hospital discharge decision making in response to system stress: a qualitative study

BMC Health Services Research
Background The purpose of this qualitative study was to identify emergent rehabilitation innovations and clinician perceptions influencing their implementation and outcomes related to hospital discharge decision-making during the Coronavirus 2019 ...
Allison M. Gustavson, Matthew J. Miller, Natassia Boening, Emily M. Hudson, Jennifer P. Wisdom, Robert E. Burke, Hildi J. Hagedorn   +6 more
doaj   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Estimating the Joint Probability Density for Index Construction: Some Simplifications Using the TWEAK as Example

International Journal of Methods in Psychiatric Research
Background Index construction using the joint probability density (JPD) method is extremely robust and, unlike confirmatory factor analysis (CFA) or item response theory (IRT), puts few restrictions on underlying data.
Maureen Murdoch, Barbara Ann Clothier, Siamak Noorbaloochi   +2 more
doaj   +1 more source

Health Care Reform and Mental Health Care Delivery [PDF]

Psychiatric Services, 2010
Vidhya, Alakeson, Richard G, Frank
openaire   +2 more sources