Results 81 to 90 of about 2,178,752 (317)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effectiveness of Community Based Safe Motherhood Promoters in Improving the Utilization of Obstetric care. The Case of Mtwara Rural District in Tanzania. [PDF]

, 2010
In Tanzania, maternal mortality ratio remains unacceptably high at 578/100,000 live births. Despite a high coverage of antenatal care (96%), only 44% of deliveries take place within the formal health services.
Declare Mushi, Rose Mpembeni, Albrecht Jahn, UNICEF, ICM/FIGO, UN, National Bureau of Statistics, SN Massawe, F Font, National Bureau of Statistics {Tanzania} & Macro International Inc. 1997, E Urassa, KM Moore, S Thaddeus, RS Ross, M Kowalewski, M Rosato, J Elder, A Kleinman, MotherCare Matters, E Murray, C Santarelli, WHO, SB Rifkin, T Lankester, B Nwakoby, JS Kiwanuka, United Nation., A Jahn, D Mushi, J Lennon, D Werner, Tanzania Ministry of Health, District Medical Officer, E Essien, U Lehmann, HB Kendah, BN Nwakoby, S Jessop, S Rowland, B Kunene, BC Mullany, District Medical Officer, G Walraven, M Thorogood   +43 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Determinants of maternal health care utilisation in India : Evidence from a recent household survey [PDF]

In India, utilisation of basic health services has remained poor. The reasons may be low levels of household income, high illiteracy and ignorance, and a host of traditional factors.
Shariff, Abusaleh, Singh, Geeta
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Critical care delivery across health care systems in low-income and low-middle-income country settings: A systematic review. [PDF]

J Glob Health, 2023
Bartlett ES, Lim A, Kivlehan S, Losonczy LI, Murthy S, Lowsby R, Papali A, Raees M, Seth B, Cobb N, Brotherton J, Dippenaar E, Nepal G, Shrestha GS, Kuo SE, Skrabal JR, Davis M, Lay C, Yi S, Jaung M, Chaffay B, Sefa N, Yang ML, Stephens PA, Rashed A, Benzoni N, Velasco B, Adhikari NK, Reynolds T.   +28 more
europepmc   +1 more source

Role of School-Based Health Centers Under Universal Coverage for Children and Youth in California: Issues and Options [PDF]

, 2007
Examines challenges of and provides suggestions for a universal model of health care delivery for all children and youth in California.
Nancy Torrey, Steve Rosenberg
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

The Health Care Financing Maze for Working-Age People with Disabilities [PDF]

, 2007
Much of the research on health care financing for people with disabilities has focused on the Medicaid and Medicare programs. The findings of this research often highlight the inadequacies of those programs in providing appropriate services to address ...
Goodman, Nanette, Livermore, Gina A, O\u27Day, Bonnie, Stapleton, David C.   +3 more
core   +3 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source