Results 91 to 100 of about 919,987 (306)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Machine learning models predicting inpatient falls
Scientific ReportsAccurate prediction of inpatient fall risk is crucial for preventing injuries and improving patient safety in hospitals. The widely used Hester-Davis score (HD) lacks precision, highlighting the need for more advanced models.
Hojjat Salehinejad +5 more
doaj +1 more source
The use of experimental vignette studies to identify drivers of variations in the delivery of health care: a scoping review. [PDF]
BMC Med Res Methodol, 2021 Sheringham J, Kuhn I, Burt J.
europepmc +1 more source
The Health Care Systems Research Network (HCSRN) comprises 20 learning health systems with integrated care delivery and embedded research units. The network’s annual conference serves as a forum for research teams from member institutions to disseminate ...
Research Network, Health Care Systems
core +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
BMC PsychologyBackground Studies have demonstrated that medical students’ anti-fat prejudice increases over the course of training, although the mechanisms through which these prejudicial attitudes are heightened are not well understood.
Samantha R. Philip +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Unfair inequalities in health and health care [PDF]
Inequalities in health and health care are caused by different factors. Measuring "unfair"inequalities implies that a distinction is introduced between causal variables leading toethically legitimate inequalities and causal variables leading to ethically
FLEURBAEY, Marc, SCHOKKAERT, Erik
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FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Digital Health & Care Innovation Centre Phase 2 – Year 3 Annual Report (August 2021 to July 2022) [PDF]
, 2022 This Year 3 annual report sets out the significant impact made by DHI over the past 12 months with continued success to report evident, including 5 projects transferred to other organisations as ready to scale.
Digital Health & Care Institute (DHI)
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