Results 71 to 80 of about 169,950,942 (293)

Decentralization and Public Delivery of Health Care Services in India [PDF]

This paper examines delivery of public health care services in India, in the broader context of decentralization. It provides an overview of the basic features and recent developments in intergovernmental fiscal relations and accountability mechanisms ...
Singh, Nirvikar
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Utilisation of Postnatal Care among Rural Women in Nepal [PDF]

, 2007
Background: Postnatal care is uncommon in Nepal, and where it is available the quality is often poor. Adequate utilisation of postnatal care can help reduce mortality and morbidity among mothers and their babies.
van Teijlingen Edwin R, Simkhada Padam P, Van Teijlingen R, Edwin, Stephens Jane, Dhakal, Sulochana, Chapman, Glyn N, Simkhada, Padam, Chapman Glyn N, Raja, Edwin Amalraj, Dhakal Sulochana, Simkhada P, Padam, van Teijlingen, Edwin, Stephens, Jane, Raja, Amalraj E., Glyn N , Chapman, Raja Amalraj E   +15 more
core   +1 more source

Critical care delivery across health care systems in low-income and low-middle-income country settings: A systematic review. [PDF]

J Glob Health, 2023
Bartlett ES, Lim A, Kivlehan S, Losonczy LI, Murthy S, Lowsby R, Papali A, Raees M, Seth B, Cobb N, Brotherton J, Dippenaar E, Nepal G, Shrestha GS, Kuo SE, Skrabal JR, Davis M, Lay C, Yi S, Jaung M, Chaffay B, Sefa N, Yang ML, Stephens PA, Rashed A, Benzoni N, Velasco B, Adhikari NK, Reynolds T.   +28 more
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Understanding medical trainees’ anti-fat dislike: roles of observed weight stigma, body image disturbance, and controllability beliefs

BMC Psychology
Background Studies have demonstrated that medical students’ anti-fat prejudice increases over the course of training, although the mechanisms through which these prejudicial attitudes are heightened are not well understood.
Samantha R. Philip, Sherecce A. Fields, Bo Zhang, Erin C. Standen, Michelle van Ryn, Sean M. Phelan   +5 more
doaj   +1 more source

Physical distancing for care delivery in health care settings: Considerations and consequences. [PDF]

Am J Infect Control, 2021
Parmasad V, Keating JA, Carayon P, Safdar N.   +3 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source