Results 71 to 80 of about 919,987 (306)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The influences of distance on health facility delivery in rural Zambia [PDF]
Skilled attendance at delivery is crucial for decreasing maternal and neonatal mortality. My literature review showed that epidemiological research on factors influencing whether women receive skilled attendance has so far been hampered by a lack of ...
Gabrysch, Sabine
core +1 more source
Quality requirements for cross-border care in Europe: a qualitative study of patients', professionals' and healthcare financiers' views. [PDF]
, 2009 BACKGROUND: In the past decade the issue of patient mobility has emerged on the European health policy agenda. Although the volume of patients crossing borders to obtain healthcare is low, it is increasing continuously and, due to its legal, financial ...
Vallejo, P +13 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Changing roles and responses of health care workers in HIV treatment and care.
, 2008 A key limiting factor in the scale up and sustainability of HIV care and treatment programmes is the global shortage of trained health care workers. This paper discusses why it is important to move beyond conceptualising health care workers simply as ...
Palmer, Natasha, Rajaraman, Divya
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Still too far to walk: literature review of the determinants of delivery service use. [PDF]
, 2009 BACKGROUND: Skilled attendance at childbirth is crucial for decreasing maternal and neonatal mortality, yet many women in low- and middle-income countries deliver outside of health facilities, without skilled help.
Campbell, Oona MR +5 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Towards quality of care i n mental health services
, 2019 Mental health is an integral part of health and is defined as “a state of mental well being where an individual realises their full potential, can cope with the normal stresses of life and can contribute productively to their community” (WHO).
Ministry of Health and Child Care +1 more
core +1 more source
The Health Care Systems Research Network (HCSRN) comprises 19 learning health systems with integrated care delivery and embedded research units. The network’s annual conference serves as a forum for research teams from member institutions to disseminate ...
Research Network, Health Care Systems
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