Results 61 to 70 of about 3,396,568 (293)

Postsurgical Remote Patient Monitoring Outcomes and Perceptions: A Mixed-Methods Assessment

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2022
Objective: To determine how postsurgical remote patient monitoring (RPM) influences readmissions and emergency visits within 30 days of discharge after operation and to understand patient and surgeon perspectives on postsurgical RPM. Patients and Methods:
Aaron Spaulding, PhD, Erica Loomis, MD, Emily Brennan, MPH, Diane Klein, BA, Karlyn Pierson, MAN, RN, Rochelle Willford, RN, M. Susan Hallbeck, PhD, Janani Reisenauer, MD   +7 more
doaj  

ChatGPT for Us: Preserving Data Privacy in ChatGPT via Dialogue Text Ambiguation to Expand Mental Health Care Delivery [PDF]

EMBC 2023, 2023
Large language models have been useful in expanding mental health care delivery. ChatGPT, in particular, has gained popularity for its ability to generate human-like dialogue. However, data-sensitive domains -- including but not limited to healthcare -- face challenges in using ChatGPT due to privacy and data-ownership concerns.
arxiv  

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

Book review of “Here, there, everywhere—A memoir” by Peter Almond

, 2022
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022.
Bruce J. Gerbi
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Decision Support Framework for Home Health Caregiver Allocation Using Optimally Tuned Spectral Clustering and Genetic Algorithm [PDF]

arXiv, 2023
Population aging is a global challenge, leading to increased demand for health care and social services for the elderly. Home Health Care (HHC) is a vital solution to serve this segment of the population. Given the increasing demand for HHC, it is essential to coordinate and regulate caregiver allocation efficiently.
arxiv  

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

Evaluation for clinical benefit of metformin in patients with idiopathic pulmonary fibrosis and type 2 diabetes mellitus: a national claims-based cohort analysis

Respiratory Research, 2022
Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with high morbidity and limited treatment options. Type 2 diabetes mellitus (T2DM) is a common comorbid illness among patients with IPF and is often treated with ...
Taylor T. Teague, Stephanie R. Payne, Bryan T. Kelly, Timothy M. Dempsey, Rozalina G. McCoy, Lindsey R. Sangaralingham, Andrew H. Limper   +6 more
doaj   +1 more source

Designing Technologies for Value-based Mental Healthcare: Centering Clinicians' Perspectives on Outcomes Data Specification, Collection, and Use [PDF]

Health information technologies are transforming how mental healthcare is paid for through value-based care programs, which tie payment to data quantifying care outcomes. But, it is unclear what outcomes data these technologies should store, how to engage users in data collection, and how outcomes data can improve care.
arxiv   +1 more source