Results 81 to 90 of about 7,677,076 (348)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Drug delivery to and through the skin

Drug Delivery and Translational Research
Drug delivery technology has advanced significantly over >50 years, and has produced remarkable innovation, countless publications and conferences, and generations of talented and creative scientists.
Richard H. Guy
semanticscholar   +1 more source

Topical Delivery of Meloxicam using Liposome and Microemulsion Formulation Approaches

, 2020
The aim of this study is to develop, characterize and compare conventional liposome, deformable liposome (transfersome) and microemulsion formulations as potential topical delivery systems for meloxicam.
Anna Froelich, Zhang, Julia, Bozena Michniak-Kohn, Julia Zhang, Froelich, Anna, Michniak-Kohn, Bozena   +5 more
core   +1 more source

Beyond multimedia adaptation: Quality of experience-aware multi-sensorial media delivery [PDF]

, 2015
Multiple sensorial media (mulsemedia) combines multiple media elements which engage three or more of human senses, and as most other media content, requires support for delivery over the existing networks.
Yuan, Zhenhui, Muntean, Gabriel-Miro, Ghinea, G, Yuan, Z, Muntean, G-M, Ghinea, Gheorghita, Gheorghita Ghinea, Gabriel-miro Muntean, Zhenhui Yuan   +8 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Delivery of new terms and concepts in a given department

Ikala: Revista de Lenguaje y Cultura, 1998
This article presents a necessary and important preparation phase of the methodology in terminology. This methodological procedure preliminary to the terminological research in the specific area of Somatic Culture, demands processes enrooted in the ...
Maria Cecilia Plested Alvarez, Angela María Campo, Gabriel Angel Quiroz Herrera, Carlos Arturo Muñoz Torres   +3 more
doaj  

Non-Invasive Delivery of Therapeutics into the Brain: The Potential of Aptamers for Targeted Delivery

Biomedicines, 2020
The blood-brain barrier (BBB) is a highly specialised network of blood vessels that effectively separates the brain environment from the circulatory system.
Bakhtiar Bukari, Rasika M. Samarasinghe, Jinjutha Noibanchong, Sarah L. Shigdar   +3 more
doaj   +1 more source

A journey through the history of PEGylated drug delivery nanocarriers

Drug Delivery and Translational Research
This note aims to inspire through providing a personal view of the development and potential Drug Delivery Nanocarriers functionalized with polythyleneglycol (PEG).
Ana M López-Estévez, Ruxandra Gref, María J. Alonso   +2 more
semanticscholar   +1 more source

The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants' life: a systematic review

BMC Gastroenterology, 2016
BackgroundThe human gut is the habitat for diverse and dynamic microbial ecosystem. The human microbiota plays a critical role in functions that sustain health and is a positive asset in host defenses.
E. Rutayisire, Kun Huang, Yehao Liu, F. Tao   +3 more
semanticscholar   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source