Results 61 to 70 of about 2,427,943 (336)
Espace populations sociétés, 2023 With more than 100 million inhabitants, Egypt is a demographic giant. Nowadays, the country wins one million inhabitants every 7 months and its population is extremely young: two thirds of Egyptians are less than 30 years old.
Florian Bonnefoi
doaj +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
H-vectors of simplicial complexes with Serre's conditions
, 2009 We study $h$-vectors of simplicial complexes which satisfy Serre's condition ($S_r$). We say that a simplicial complex $\Delta$ satisfies Serre's condition ($S_r$) if $\tilde H_i(\lk_\Delta(F);K)=0$ for all faces $F \in \Delta$ and for all $i < \min \{r ...
Murai, Satoshi, Terai, Naoki
core +1 more source
Specific Increase of Hippocampal Delta Oscillations Across Consecutive Treadmill Runs
Frontiers in Behavioral Neuroscience, 2020 Running speed affects theta (6–10 Hz) oscillations, the most prominent rhythm in the rat hippocampus. Many reports have found a strong positive correlation between locomotion speed and the amplitude and frequency of theta oscillations.
Alan M. B. Furtunato +8 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
COVID-19 Cases and Disease Severity in Pregnancy and Neonatal Positivity Associated With Delta (B.1.617.2) and Omicron (B.1.1.529) Variant Predominance [PDF]
, 2022 Emily H. Adhikari +5 more
openalex +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Reproduction Number of the Omicron Variant Triples That of the Delta Variant [PDF]
, 2022 Zhanwei Du +10 more
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Hydrology as a Driver of Floating River Plastic Transport
Earth's Future, 2022 Plastic pollution in aquatic ecosystems is a growing threat to ecosystem health and human livelihood. Recent studies show that the majority of environmental plastics accumulate within river systems for years, decades and potentially even longer.
T. vanEmmerik +20 more
doaj +1 more source