Results 71 to 80 of about 2,320,019 (294)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Remote Sensing for the Quantification of Land Surface Dynamics in Large River Delta Regions—A Review
Remote Sensing, 2019 River deltas and estuaries belong to the most significant coastal landforms on our planet and are usually very densely populated. Nearly 600 million people live in river deltas, benefiting from the large variety of locational advantages and rich ...
Claudia Kuenzer +3 more
doaj +1 more source
Decreased memory B cell frequencies in COVID‐19 delta variant vaccine breakthrough infection
EMBO Molecular Medicine, 2022 The SARS‐CoV‐2 Delta (B.1.617.2) variant is capable of infecting vaccinated persons. An open question remains as to whether deficiencies in specific vaccine‐elicited immune responses result in susceptibility to vaccine breakthrough infection.
Matthew Zirui Tay +29 more
doaj +1 more source
On the width of N-Delta and Delta-Delta states
, 2016 It is seen by a coupled-channel calculation that in the two-baryon N-Delta or Delta-Delta system the width of the state is greatly diminished due to the relative kinetic energy of the two baryons, since the internal energy of the particles, available for pionic decay, is smaller. A similar state dependent effect arises from the centrifugal barrier in N-
openaire +2 more sources
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
, 2011 We analyze the position and momentum uncertainties of the energy eigenstates of the harmonic oscillator in the context of a deformed quantum mechanics, namely, that in which the commutator between the position and momentum operators is given by [x,p]=i ...
I. S. Gradshteyn +3 more
core +2 more sources
Journal of Knot Theory and Its Ramifications, 2016 We call a delta diagram any diagram of a knot or link whose regions (including the unbounded one) have 3, 4, or 5 sides. We prove that any knot or link admits a delta diagram. We define and estimate combinatorial link invariants stemming from this definition.
Jablan, Slavik +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Hydrobiological Investigation of Channels in the Mouth Region of the Lena River [PDF]
Учёные записки Казанского университета: Серия Естественные науки, 2015 The current taxonomic composition, structure, and quantitative characteristics of zooplankton in channels of the mouth region of the Lena River were considered.
G.R. Nigamatzyanova +3 more
doaj
$\pi \Delta\Delta$ coupling constant
, 2000 We calculate the $\pi \Delta\Delta$ coupling $g_{\pi^0\Delta^{++}\Delta^{++}}$ using light cone QCD sum rule.
B. Sakita +15 more
core +1 more source