Results 41 to 50 of about 326,141 (263)

Iterative solution of elliptic equations

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2022
We reduce solution of the Dirichlet problem ($x \in D \subset R^m$) \[ \Delta u(x)+a(x)u(x)=f(x) \quad \mbox{in $D$}, \qquad u=0 \quad \mbox{on $\partial D$} \] to iterative solution of a simpler problem \[ \Delta u=f(x) \; \; \mbox{in $D$}, \; \; u=0
Philip Korman, Dieter Schmidt
doaj   +1 more source

Delta method, asymptotic distribution

open access: yesWIREs Computational Statistics, 2023
AbstractThe delta method for deriving asymptotic distributions is presented. Assume interest lies in where is an unknown parameter and is a known function. The delta method allows to immediately obtain an approximation of the distribution of the plug‐in estimator through the asymptotic distribution ofwheneverthe asymptotic distribution of is known and ...
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Delta Methods in Enveloping Algebras of Lie Superalgebras [PDF]

open access: yesTransactions of the American Mathematical Society, 1992
Let L L be a Lie superalgebra over a field
Bergen, J., Passman, D.S.
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Collisional {delta}f method [PDF]

open access: yes, 1997
A general method for including various collisional effects, such as the drag and diffusion of test particles due to background plasmas, the effect of particle source and sink, and the like-particle Coulomb collisions, is presented. The marker density g is generally unknown along the particle trajectory, and its evaluation depends on the way particles ...
Chen, Y., White, R. B.
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Determining Minimum Trial Numbers for Reliable Lameness Detection in Canine Kinematic Studies

open access: yesAnimals
Visual orthopedic gait assessment in dogs is recognized as subjective and is limited by interobserver variability. Objective detection of lameness is offered by biomechanical analysis, where asymmetry between limbs is quantified through kinematic ...
Isabel Marrero   +2 more
doaj   +1 more source

Mathematical Explanation and Fault Diagnosis of Low Delta-T Syndrome in Building Chilled Water Systems

open access: yesBuildings, 2018
Low delta-T syndrome often occurs in building chilled water systems, which makes systems fail to operate as efficiently as originally anticipated. Extensive studies have been conducted on the subject of low delta-T syndrome with the aims of investigating
Chengchu Yan, Xiuxiu Yang, Yizhe Xu
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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