Results 41 to 50 of about 11,724,681 (306)

Delta method, asymptotic distribution

open access: yesWIREs Computational Statistics, 2023
AbstractThe delta method for deriving asymptotic distributions is presented. Assume interest lies in where is an unknown parameter and is a known function. The delta method allows to immediately obtain an approximation of the distribution of the plug‐in estimator through the asymptotic distribution ofwheneverthe asymptotic distribution of is known and ...
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Delta Methods in Enveloping Algebras of Lie Superalgebras [PDF]

open access: yesTransactions of the American Mathematical Society, 1992
Let L L be a Lie superalgebra over a field
Bergen, J., Passman, D.S.
openaire   +2 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Delta High P.T.A. Officers

open access: yes, 1965
Left to Right: Mrs. Ronald Wright-Secretary, Mrs. Robert Clark-President, Mrs. Dorcey Sabey-Vice President being presented the P.T.A. duties by Mrs.

core   +1 more source

Delta Delta Delta welcomes you to Ole Miss [PDF]

open access: yes, 2019
Sorority recruitment brochure, circa 1959, for Delta Delta Delta at the University of Mississippihttps://egrove.olemiss.edu/um_pub/1015/thumbnail ...
Delta Delta Delta. Tri Delta Chapter (University of Mississippi)
core   +1 more source

The performance of delta check methods.

open access: yesClinical Chemistry, 1979
Abstract The percentage of mislabeled specimens detected (true-positive rate) and the percentage of correctly labeled specimens misidentified (false-positive rate) were computed for three previously proposed delta check methods and two linear discriminant functions.
L B, Sheiner, L A, Wheeler, J K, Moore
openaire   +2 more sources

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

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