Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease [PDF]
The source of the severe acute respiratory syndrome (SARS) epidemic was traced to wildlife market civets and ultimately to bats. Subsequent hunting for novel coronaviruses (CoVs) led to the discovery of two additional human and over 40 animal CoVs ...
Chan, JFW +5 more
core +1 more source
Structural Immunology of SARS‐CoV‐2
ABSTRACT The SARS‐CoV‐2 spike (S) protein has undergone significant evolution, enhancing both receptor binding and immune evasion. In this review, we summarize ongoing efforts to develop antibodies targeting various epitopes of the S protein, focusing on their neutralization potency, breadth, and escape mechanisms.
Meng Yuan, Ian A. Wilson
wiley +1 more source
Complete Genome Characterization of Novel Chinese Porcine Deltacoronavirus Strain SD
ABSTRACT A porcine deltacoronavirus (PDCoV) was isolated and identified from feces of diarrheic piglets in Shandong Province of the Chinese mainland, and the complete genome of the Chinese PDCoV strain, SD, was sequenced and analyzed to further characterize PDCoV circulating in China.
Liu, Can +5 more
openaire +2 more sources
Emergence of Thailand‐like strains of porcine deltacoronavirus in Guangxi Province, China [PDF]
Haixin Huang +7 more
openalex +1 more source
Identification and subcellular localization of porcine deltacoronavirus accessory protein NS6
Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus. Accessory proteins are genus-specific for coronavirus, and two putative accessory proteins, NS6 and NS7, are predicted to be encoded by PDCoV; however, this remains to be confirmed experimentally.
Fang, Puxian +9 more
openaire +2 more sources
Porcine deltacoronavirus and its prevalence in China: a review of epidemiology, evolution, and vaccine development [PDF]
Pan Tang +4 more
openalex +1 more source
Distribution and Regulation of RIG‐I in Porcine Intestine During TGEV and PDCoV Infection
Transmissible gastroenteritis virus (TGEV) and porcine deltacoronavirus (PDCoV) are major enteric coronaviruses responsible for severe diarrhea in neonatal piglets. Retinoic acid‐inducible gene I (RIG‐I) is a key sensor against RNA viruses, yet its distribution in the porcine intestine and regulatory roles during TGEV and PDCoV infections remain ...
Hui Zeng +7 more
wiley +1 more source
Characterization and Pathogenicity of the Porcine Deltacoronavirus Isolated in Southwest China
Porcine deltacoronavirus (PDCoV) is a newly emerging enteric pathogen in swine that causes diarrhea in neonatal piglets and creates an additional economic burden on porcine industries in Asia and North America. In this study, a PDCoV isolate, CHN-SC2015,
Yujia Zhao +12 more
doaj +1 more source
Swine enteric coronaviruses (SeCoVs) cause acute enteritis and high mortality in neonatal piglets, posing a significant threat to the swine industry. Injectable vaccines often fail to induce effective mucosal immunity, and their efficacy is further compromised by maternally derived antibodies.
Qihao Pan +14 more
wiley +1 more source
The analysis of biological diversity of coronaviruses contributes in the early awareness of their zoonotic spreading [PDF]
The recent outbreak of COVID-19 rose a new wave of interest to coronaviruses though the first coronaviruses were discovered in the first half of the 20th century. That time coronaviruses were considered as a quite serious veterinary problem but they were
Khaitovich, Aleksandr B. +3 more
core +1 more source

