Results 101 to 110 of about 4,018 (187)

HSP90AB1 is a host factor that promotes porcine deltacoronavirus replication

Journal of Biological Chemistry
Porcine deltacoronavirus (PDCoV) is an emerging enteropathogenic coronavirus. It causes mortality in neonatal piglets and is of growing concern because of its broad host range, including humans. To date, the mechanism of PDCoV infection remains poorly understood. Here, based on a genome-wide CRISPR screen of PDCoV-infected cells, we found that HSP90AB1
Zhao, Yujia, Yuan, Jianlin, Xiao, Dai, Zhang, Luwen, Li, Cheng, Hu, Jingfei, Chen, Rui, Song, Daili, Wen, Yiping, Wu, Rui, Zhao, Qin, Du, Senyan, Yan, Qigui, Han, Xinfeng, Wen, Xintian, Cao, Sanjie, Huang, Xiaobo   +16 more
openaire   +2 more sources

Identification and subcellular localization of porcine deltacoronavirus accessory protein NS6

Virology, 2016
Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus. Accessory proteins are genus-specific for coronavirus, and two putative accessory proteins, NS6 and NS7, are predicted to be encoded by PDCoV; however, this remains to be confirmed experimentally.
Fang, Puxian, Fang, Liurong, Liu, Xiaorong, Hong, Yingying, Wang, Yongle, Dong, Nan, Ma, Panpan, Bi, Jing, Wang, Dang, Xiao, Shaobo   +9 more
openaire   +2 more sources

A novel strain of porcine deltacoronavirus in Vietnam

, 2018
Two porcine deltacoronavirus (PDCoV) strains(Binh21 and HaNoi6) were isolated from two pig farmsin North Vietnam. Phylogenetic analysis of the completegenomes and the Spike and Membrane genes revealed thatthe two Vietnam PDCoVs belong to the same lineage
Van Phan Le...[et al.]
core  

Detection and phylogenetic analysis of porcine deltacoronavirus in Korean swine farms, 2015

, 2016
This study applied molecular-based method to investigate the presence of porcine deltacoronavirus (PDCoV) in 59 commercial pig farms in South Korea. The results of RT-PCR screening on a relatively large collection of faeces samples (n = 681) from January
J H Lee, H C CHung, B K Park, H J Moon, S J Park, C H Lee, V G Nguyen, G E Lee, Hye Kwon Kim   +8 more
core   +1 more source

Functional characterization and proteomic analysis of the nucleocapsid protein of porcine deltacoronavirus

Virus Research, 2015
Porcine deltacoronavirus (PDCoV) is a newly discovered enterotropic swine coronavirus that causes enteritis and diarrhea in piglets. Like other coronaviruses, PDCoV commonly contains 4 major structural proteins: spike (S), envelope (E), membrane (M), and nucleocapsid (N) proteins.
Lee, Sunhee, Lee, Changhee
openaire   +2 more sources

Detection and genomic characterization of coronaviruses among migratory birds in Guangdong Province, China

Animal Diseases
The recent Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic highlights the significant threat coronaviruses (CoVs) pose to public health.
Yingjie Lian, Ying Huang, Lixia Xie, Quan Liu, Zhengkai Wei, Runfeng Shi, Xinhong Pan, Wenfen Zhang, Jun Ma, Juntao Li   +9 more
doaj   +1 more source

Porcine Coronavirus HKU15 Detected in 9 US States, 2014

Emerging Infectious Diseases, 2014
Leyi Wang, Beverly Byrum, Yan Zhang
doaj   +1 more source

Identification of novel serological agents for porcine deltacoronavirus infection based on the immunogenic accessory protein NS6

Animal Diseases
Porcine deltacoronavirus (PDCoV) is a swine enteropathogenic CoV that causes severe vomiting, diarrhea and dehydration in suckling piglets, leading to economic losses in the swine industry.
Yali Li, Fangshu Shi, Lingxiang Cao, Qiankun Zheng, Yaoyu Feng, Bin Wang, Yaowei Huang   +6 more
doaj   +1 more source

Cryo-Electron Microscopy Structure of Porcine Deltacoronavirus Spike Protein in the Prefusion State

, 2018
Coronavirus spike proteins from different genera are divergent, although they all mediate coronavirus entry into cells by binding to host receptors and fusing viral and cell membranes. Here, we determined the cryo-electron microscopy structure of porcine
Qibin Geng, Wei Zhang, Chang Liu, Wanbo Tai, Lanying Du, Yuan Zheng, Jian Shang, Yang Yang, Yusen Zhou, Fang Li   +9 more
core   +1 more source

Characterization of two neutralizing monoclonal antibodies with conformational epitopes against porcine deltacoronavirus

Porcine deltacoronavirus (PDCoV) is a globally distributed swine enteropathogenic virus that emerged in the last decade. A recent report of PDCoV infection in Haitian children also highlights potential public health implications.
Bin Wang, Priscilla F. Gerber, Dong Yang, Yangyang Sun, Xiangdong Li, Wan Lu, Yongle Yang, Hongtao Cao, Yaowei Huang   +8 more
core   +1 more source