Results 101 to 110 of about 6,150 (245)

Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease [PDF]

open access: yes, 2015
The source of the severe acute respiratory syndrome (SARS) epidemic was traced to wildlife market civets and ultimately to bats. Subsequent hunting for novel coronaviruses (CoVs) led to the discovery of two additional human and over 40 animal CoVs ...
Chan, JFW   +5 more
core   +1 more source

Structural Immunology of SARS‐CoV‐2

open access: yesImmunological Reviews, Volume 329, Issue 1, January 2025.
ABSTRACT The SARS‐CoV‐2 spike (S) protein has undergone significant evolution, enhancing both receptor binding and immune evasion. In this review, we summarize ongoing efforts to develop antibodies targeting various epitopes of the S protein, focusing on their neutralization potency, breadth, and escape mechanisms.
Meng Yuan, Ian A. Wilson
wiley   +1 more source

Complete Genome Characterization of Novel Chinese Porcine Deltacoronavirus Strain SD

open access: yesGenome Announcements, 2017
ABSTRACT A porcine deltacoronavirus (PDCoV) was isolated and identified from feces of diarrheic piglets in Shandong Province of the Chinese mainland, and the complete genome of the Chinese PDCoV strain, SD, was sequenced and analyzed to further characterize PDCoV circulating in China.
Liu, Can   +5 more
openaire   +2 more sources

Emergence of Thailand‐like strains of porcine deltacoronavirus in Guangxi Province, China [PDF]

open access: gold, 2020
Haixin Huang   +7 more
openalex   +1 more source

Identification and subcellular localization of porcine deltacoronavirus accessory protein NS6

open access: yesVirology, 2016
Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus. Accessory proteins are genus-specific for coronavirus, and two putative accessory proteins, NS6 and NS7, are predicted to be encoded by PDCoV; however, this remains to be confirmed experimentally.
Fang, Puxian   +9 more
openaire   +2 more sources

Distribution and Regulation of RIG‐I in Porcine Intestine During TGEV and PDCoV Infection

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Transmissible gastroenteritis virus (TGEV) and porcine deltacoronavirus (PDCoV) are major enteric coronaviruses responsible for severe diarrhea in neonatal piglets. Retinoic acid‐inducible gene I (RIG‐I) is a key sensor against RNA viruses, yet its distribution in the porcine intestine and regulatory roles during TGEV and PDCoV infections remain ...
Hui Zeng   +7 more
wiley   +1 more source

Characterization and Pathogenicity of the Porcine Deltacoronavirus Isolated in Southwest China

open access: yesViruses, 2019
Porcine deltacoronavirus (PDCoV) is a newly emerging enteric pathogen in swine that causes diarrhea in neonatal piglets and creates an additional economic burden on porcine industries in Asia and North America. In this study, a PDCoV isolate, CHN-SC2015,
Yujia Zhao   +12 more
doaj   +1 more source

Design of Mucosal Vaccines Against Swine Enteric Coronaviruses: From Antigen Delivery to Immune Activation

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Swine enteric coronaviruses (SeCoVs) cause acute enteritis and high mortality in neonatal piglets, posing a significant threat to the swine industry. Injectable vaccines often fail to induce effective mucosal immunity, and their efficacy is further compromised by maternally derived antibodies.
Qihao Pan   +14 more
wiley   +1 more source

The analysis of biological diversity of coronaviruses contributes in the early awareness of their zoonotic spreading [PDF]

open access: yes, 2021
The recent outbreak of COVID-19 rose a new wave of interest to coronaviruses though the first coronaviruses were discovered in the first half of the 20th century. That time coronaviruses were considered as a quite serious veterinary problem but they were
Khaitovich, Aleksandr B.   +3 more
core   +1 more source

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