Results 1 to 10 of about 3,368 (205)

Porcine Deltacoronavirus-Related Viruses in House Sparrows [PDF]

Viruses
Porcine deltacoronavirus (PDCoV) is an emerging enteric pathogen in pigs and a newly recognized zoonotic coronavirus in humans. Genetic analyses suggest that PDCoV originated from avian deltacoronaviruses, with sparrow deltacoronaviruses (SpDCoVs) being ...
Daoqun Li, Jiayu Xu, Elizabeth M. Ames, Mingde Liu, Bikash Aryal, Maria Chellis, Ramon Zegpi Lagos, Christopher M. Tonra, Qiuhong Wang   +8 more
doaj   +4 more sources

CRISPR/Cas13a-based rapid detection method for porcine deltacoronavirus [PDF]

Frontiers in Microbiology
BackgroundPorcine deltacoronavirus (PDCoV) is a newly discovered porcine intestinal pathogenic coronavirus with a single-stranded positive-sense RNA genome and an envelope.
Ran Luo, Zhimeng Cheng, Zhimeng Cheng, Haoyu Wang, Qiyue Yang, Yongping Zeng, Yijun Yang, Yuankun Chen, Wenting Li, Wenting Li, Xiao Liu, Xiao Liu   +11 more
doaj   +4 more sources

Inhibition of porcine deltacoronavirus entry and replication by Cepharanthine [PDF]

Virus Research, 2023
Porcine deltacoronavirus (PDCoV) is an emerging swine enteropathogenic coronavirus (CoV) that mainly causes acute diarrhea/vomiting, dehydration, and mortality in piglets, possessing economic losses and public health concerns.
Yumei Sun, Zhongzhu Liu, Shiyi Shen, Mengjia Zhang, Lina Liu, Ahmed H Ghonaim, Yongtao Li, Shujun Zhang, Wentao Li   +8 more
doaj   +4 more sources

Porcine deltacoronavirus infection promotes intracellular lipid droplet accumulation [PDF]

Virology Journal
Background Viruses critically depend on host lipid metabolism to drive replication, assembly and immune evasion during infection and pathogenesis. While previous studies have demonstrated that certain viruses induce lipid droplet accumulation in infected
Xiaohui Yang, Haiwen Zhong, Chuanzhao Yu, Jie Cheng, Huijie Jiang, Cuizhen Wang, Changxu Song, Huaqiang Yang   +7 more
doaj   +3 more sources

Differential Susceptibility to Porcine Deltacoronavirus: Ducks Show Greater Vulnerability Than Geese. [PDF]

Transbound Emerg Dis
Porcine deltacoronavirus (PDCoV), an enteropathogenic coronavirus belonging to the Deltacoronavirus genus, is globally distributed and represents a significant viral enteric disease in pigs. It primarily causes severe diarrhea in pigs, especially in newborn piglets, with high fatality rates, resulting in substantial losses to the pig farming industry ...
Liu R, Meng S, Shuai L, Zhang H, Hu G, Guo H, Chen J, Shan D, Du Y, Cao Y, Bu Z, Wen Z.   +11 more
europepmc   +2 more sources

Development of a nanobody-based competitive enzyme-linked immunosorbent assay for the sensitive detection of antibodies against porcine deltacoronavirus [PDF]

Journal of Clinical Microbiology
Porcine deltacoronavirus (PDCoV) is an emerging porcine enteric coronavirus causing significant economic losses to the pig farming industry globally.
Ruiming Yu, Liping Zhang, Yingjie Bai, Peng Zhou, Jun Yang, Dongsheng Wang, Liyang Wei, Zhongwang Zhang, Chenghua Yan, Yonglu Wang, Huichen Guo, Li Pan, Ligang Yuan, Xinsheng Liu   +13 more
doaj   +2 more sources

Development and Comparison of Indirect ELISAs for Detecting IgG and IgA Antibodies Against Major Structural Proteins of Porcine Deltacoronavirus With Virus Neutralization as a Benchmark. [PDF]

Transbound Emerg Dis
Porcine deltacoronavirus (PDCoV) is an emerging enteric pathogen that causes substantial economic losses in the global swine industry. Although neutralizing antibodies (NAbs) are a key indicator of vaccine efficacy, their diagnostic concordance with IgG/IgA levels measured by indirect enzyme‐linked immunosorbent assays (iELISAs) targeting major ...
Li D, Deng J, Zhang Y, Wang Z, Li Y, Hao L, Tian K, Li X.   +7 more
europepmc   +2 more sources

Genetic and Pathogenic Characterization of a Porcine Deltacoronavirus Strain Isolated in Zhejiang Province, China. [PDF]

Transbound Emerg Dis
Porcine deltacoronavirus (PDCoV) has emerged as a significant pathogen in swine, affecting animal health and posing potential risks for cross‐species transmission. In this study, we successfully isolated a PDCoV strain named HZYH‐2019 from the feces of diarrheal sows in Zhejiang Province, China.
Zhang YQ, Wang B, Wei W, Lu W, Du EZ, Liu Y, Yang YL, Huang YW.   +7 more
europepmc   +2 more sources

A Previously Undiscovered Circular RNA, circTNFAIP3, and Its Role in Coronavirus Replication

mBio, 2021
Circular RNAs (circRNAs) are a newly discovered class of noncoding RNAs (ncRNAs) present in various tissues and cells. However, the functions of most circRNAs have not been verified experimentally.
Liuyang Du, Xingbo Wang, Junli Liu, Jiarong Li, Shengnan Wang, Jing Lei, Jiyong Zhou, Jinyan Gu   +7 more
doaj   +1 more source

Structures of a deltacoronavirus spike protein bound to porcine and human receptors

Nature Communications, 2022
Porcine deltacoronavirus (PDCoV) can experimentally infect a variety of animals. Human infection by PDCoV has also been reported. Consistently, PDCoV can use aminopeptidase N (APN) from different host species as receptors to enter cells.
Weiwei Ji, Qi Peng, Xueqiong Fang, Zehou Li, Yaxin Li, Cunfa Xu, Shuqing Zhao, Jizong Li, Rong Chen, Guoxiang Mo, Zhanyong Wei, Ying Xu, Bin Li, Shuijun Zhang   +13 more
doaj   +1 more source