Results 1 to 10 of about 238 (50)

A Previously Undiscovered Circular RNA, circTNFAIP3, and Its Role in Coronavirus Replication

open access: yesmBio, 2021
Circular RNAs (circRNAs) are a newly discovered class of noncoding RNAs (ncRNAs) present in various tissues and cells. However, the functions of most circRNAs have not been verified experimentally.
Liuyang Du   +7 more
doaj   +1 more source

Structures of a deltacoronavirus spike protein bound to porcine and human receptors

open access: yesNature Communications, 2022
Porcine deltacoronavirus (PDCoV) can experimentally infect a variety of animals. Human infection by PDCoV has also been reported. Consistently, PDCoV can use aminopeptidase N (APN) from different host species as receptors to enter cells.
Weiwei Ji   +13 more
doaj   +1 more source

Modulation of Innate Antiviral Immune Response by Porcine Enteric Coronavirus

open access: yesFrontiers in Microbiology, 2022
Host’s innate immunity is the front-line defense against viral infections, but some viruses have evolved multiple strategies for evasion of antiviral innate immunity.
Kunli Zhang   +7 more
doaj   +1 more source

Prevention and Control of Swine Enteric Coronaviruses in China: A Review of Vaccine Development and Application

open access: yesVaccines, 2023
Swine enteric coronaviruses (SECs) cause significant economic losses to the pig industry in China. Although many commercialized vaccines against transmissible gastroenteritis virus (TGEV) and porcine epidemic diarrhea virus (PEDV) are available, viruses ...
Fanzhi Kong   +4 more
doaj   +1 more source

Detection and Genetic Characterization of Deltacoronavirus in Pigs, Ohio, USA, 2014

open access: yesEmerging Infectious Diseases, 2014
In Ohio, United States, in early 2014, a deltacoronavirus was detected in feces and intestine samples from pigs with diarrheal disease. The complete genome sequence and phylogenetic analysis of the virus confirmed that the virus is closely related to a ...
Leyi Wang, Beverly Byrum, Yan Zhang
doaj   +1 more source

Porcine deltacoronavirus enters ST cells by clathrin-mediated endocytosis and does not require Rab5, Rab7, or Rab11

open access: yesMicrobiology Spectrum, 2023
Porcine deltacoronavirus (PDCoV) is a newly emerged enteric pathogen that causes diarrhea, dehydration, vomiting, and in suckling piglets, a high rate of death.
Shiqian Li   +11 more
doaj   +1 more source

A Review of Bioactive Compounds against Porcine Enteric Coronaviruses

open access: yesViruses, 2022
Pig diarrhea is a universal problem in the process of pig breeding, which seriously affects the development of the pig industry. Porcine enteric coronaviruses (PECoVs) are common pathogens causing diarrhea in pigs, currently including transmissible ...
Cong Duan   +3 more
doaj   +1 more source

Detection of Four Porcine Enteric Coronaviruses Using CRISPR-Cas12a Combined with Multiplex Reverse Transcriptase Loop-Mediated Isothermal Amplification Assay

open access: yesViruses, 2022
Porcine enteric coronaviruses have caused immense economic losses to the global pig industry, and pose a potential risk for cross-species transmission. The clinical symptoms of the porcine enteric coronaviruses (CoVs) are similar, making it difficult to ...
Jiajia Liu   +11 more
doaj   +1 more source

Antiviral Effect of Lithium Chloride and Diammonium Glycyrrhizinate on Porcine Deltacoronavirus In Vitro

open access: yesPathogens, 2019
Porcine deltacoronavirus (PDCoV) is an emerging global swine virus that has a propensity for interspecies transmission. It was identified in Hong Kong in 2012.
Xiaofeng Zhai   +5 more
doaj   +1 more source

Contribution of porcine aminopeptidase N to porcine deltacoronavirus infection

open access: yesEmerging Microbes and Infections, 2018
Porcine deltacoronavirus (PDCoV), a member of genus Deltacoronavirus, is an emerging swine enteropathogenic coronavirus (CoV). Although outstanding efforts have led to the identification of Alphacoronavirus and Betacoronavirus receptors, the receptor for
Xinyu Zhu   +9 more
doaj   +1 more source

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