Results 31 to 40 of about 238 (50)

Characteristics of the Life Cycle of Porcine Deltacoronavirus (PDCoV) In Vitro: Replication Kinetics, Cellular Ultrastructure and Virion Morphology, and Evidence of Inducing Autophagy

Viruses, 2019
Porcine deltacoronavirus (PDCoV) causes severe diarrhea and vomiting in affected piglets. The aim of this study was to establish the basic, in vitro characteristics of the life cycle such as replication kinetics, cellular ultrastructure, virion ...
Pan Qin, En-Zhong Du, Wen-Ting Luo, Yong-Le Yang, Yu-Qi Zhang, Bin Wang, Yao-Wei Huang   +6 more
doaj   +1 more source

Identification of novel serological agents for porcine deltacoronavirus infection based on the immunogenic accessory protein NS6

Animal Diseases
Porcine deltacoronavirus (PDCoV) is a swine enteropathogenic CoV that causes severe vomiting, diarrhea and dehydration in suckling piglets, leading to economic losses in the swine industry.
Yali Li, Fangshu Shi, Lingxiang Cao, Qiankun Zheng, Yaoyu Feng, Bin Wang, Yaowei Huang   +6 more
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Deltacoronavirus HKU11, HKU13, PDCoV (HKU15) and HKU17 spike pseudoviruses enter avian DF-1 cells via clathrin-mediated endocytosis in a Rab5-, Rab7- and pH-dependent manner

Veterinary Research
Porcine deltacoronavirus (PDCoV), also known as HKU15, is a swine enteropathogenic virus that is believed to have originated in birds. PDCoV belongs to the genus Deltacoronavirus (DCoV), the members of which have mostly been identified in diverse avian ...
Qi-Zhang Liang, Chun-Miao Ji, Bin Wang, Wei Chen, Feng Cong, Yu Huang, Yao-Wei Huang   +6 more
doaj   +1 more source

Low-pH-induced conformational changes in the spike protein promote porcine deltacoronavirus infection by enhancing viral binding efficiency to the porcine aminopeptidase receptor

Journal of Virology
Porcine deltacoronavirus (PDCoV) is a critical enteric pathogen causing severe diarrhea in neonatal piglets, with fecal-oral transmission as its primary route. However, the molecular mechanism underlying PDCoV adaptation to the acidic gastric environment
Ruiming Yu, Liping Zhang, Peng Zhou, Zhongwang Zhang, Yingjie Bai, Dongsheng Wang, Ya Liu, Xinru Wang, Gang Du, Ligang Yuan, Huichen Guo, Li Pan, Xinsheng Liu   +12 more
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Characterization and Pathogenicity of the Porcine Deltacoronavirus Isolated in Southwest China

Viruses, 2019
Porcine deltacoronavirus (PDCoV) is a newly emerging enteric pathogen in swine that causes diarrhea in neonatal piglets and creates an additional economic burden on porcine industries in Asia and North America. In this study, a PDCoV isolate, CHN-SC2015,
Yujia Zhao, Huan Qu, Jingfei Hu, Jiayu Fu, Rui Chen, Cheng Li, Sanjie Cao, Yiping Wen, Rui Wu, Qin Zhao, Qigui Yan, Xintian Wen, Xiaobo Huang   +12 more
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CRISPR/Cas13a-based rapid detection method for porcine deltacoronavirus

Frontiers in Microbiology
BackgroundPorcine deltacoronavirus (PDCoV) is a newly discovered porcine intestinal pathogenic coronavirus with a single-stranded positive-sense RNA genome and an envelope.
Ran Luo, Zhimeng Cheng, Zhimeng Cheng, Haoyu Wang, Qiyue Yang, Yongping Zeng, Yijun Yang, Yuankun Chen, Wenting Li, Wenting Li, Xiao Liu, Xiao Liu   +11 more
doaj   +1 more source

The essential role of heparan sulfate in the entry of PDCoV and other porcine coronaviruses

Virulence
Porcine enteric coronaviruses, including porcine deltacoronavirus (PDCoV), porcine epidemic diarrhea virus (PEDV), swine acute diarrhea syndrome coronavirus (SADS-CoV), and transmissible gastroenteritis coronavirus (TGEV), can cause acute diarrhea ...
Ningning Ma, Mengjia Zhang, Ahmed H. Ghonaim, Pei Zhou, Chunyan Wang, Jiaru Zhou, Guanghao Guo, Robert Jan Lebbink, Berend Jan Bosch, Hongmei Zhu, Wentao Li, Qigai He   +11 more
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Tight junction protein claudin-1 is a novel internalization factor for swine enteric coronaviruses infection

mBio
Swine enteric coronaviruses (SeCoVs), including transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), and porcine deltacoronavirus (PDCoV), have been reported to use aminopeptidase N (APN) as a cellular receptor.
Zhongyuan Li, Jianfei Chen, Yunyan Chen, Shouping Hu, Huan Li, Liang Li, Mei Xue, Li Feng   +7 more
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GSDMD and GSDME exhibit distinct roles in enteric coronavirus PDCoV-induced pyroptosis and inflammatory responses

Journal of Virology
Porcine deltacoronavirus (PDCoV), an emerging enteric coronavirus with zoonotic potential, typically causes intestinal villous epithelial cell damage with inflammation.
Chenyu Li, Yuting Shi, Chunying Xie, Kaiqi Duan, Tong Ding, Xiangfei Xu, Liurong Fang, Yanrong Zhou, Shaobo Xiao   +8 more
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Porcine Deltacoronavirus, Thailand, 2015

Emerging Infectious Diseases, 2016
Taveesak Janetanakit, Mongkol Lumyai, Napawan Bunpapong, Supanat Boonyapisitsopa, Supassama Chaiyawong, Nutthawan Nonthabenjawan, Sawang Kesdaengsakonwut, Alongkorn Amonsin   +7 more
doaj   +1 more source