Results 81 to 90 of about 4,018 (187)

Complete Genome Characterization of the Porcine Deltacoronavirus HKD/JPN/2016, Isolated in Japan, 2016

open access: yes, 2017
In 2016, an outbreak of diarrhea with high mortality in piglets occurred on a swine farm in Hokkaido prefecture, Japan. The causative porcine deltacoronavirus HDK/JPN/2016 was isolated from intestinal samples of the dead piglets on LLC-PK1 cells.
Seiichi Ohashi   +2 more
core   +1 more source

Nicotinamide Efficiently Suppresses Porcine Epidemic Diarrhea Virus and Porcine Deltacoronavirus Replication

open access: yes, 2023
Porcine epidemic diarrhea virus (PEDV) and porcine deltacoronavirus (PDCoV), members of the genus Coronavirus, mainly cause acute diarrhea, vomiting and dehydration in piglets, and thus lead to serious economic losses.
Peng Zhou   +10 more
core   +1 more source

Development of a High‐Resolution Melting (HRM)‐Based Multiplex Real‐Time PCR Assay of PEDV, TGEV, PoRV, PDCoV, PRV, and PRRSV

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Six key viral pathogens—porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), porcine rotavirus (PoRV), porcine deltacoronavirus (PDCoV), pseudorabies virus (PRV), and porcine reproductive and respiratory syndrome virus (PRRSV)—inflict substantial economic losses on the global swine industry.
Fangshan Wang   +7 more
wiley   +1 more source

Construction, Characterization and Application of Recombinant Porcine Deltacoronavirus Expressing Nanoluciferase

open access: yes, 2021
Porcine deltacoronavirus (PDCoV), an emerging enteropathogenic coronavirus, causes diarrhoea in suckling piglets and has the potential for cross-species transmission. No effective PDCoV vaccines or antiviral drugs are currently available.
Huichang Zhang   +9 more
core   +1 more source

Porcine deltacoronavirus (PDCoV) infection antagonizes interferon-λ1 production

open access: yesVeterinary Microbiology, 2020
Porcine deltacoronavirus (PDCoV) is a novel swine enteropathogenic coronavirus that causes watery diarrhea, vomiting and mortality in nursing piglets. Type III interferons (IFN-λs) are the major antiviral cytokines in intestinal epithelial cells, the target cells in vivo for PDCoV.
Liu, Shudan   +6 more
openaire   +2 more sources

Emergence of a Highly Virulent Porcine Epidemic Diarrhea Virus (PEDV) G2c Subtype in China: Isolation, Genetic and Pathogenic Characterization, and Cross‐Neutralizing Antibody Response

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine epidemic diarrhea virus (PEDV), an enteropathogenic coronavirus causing high mortality in neonatal piglets, continues to threaten global swine industries. Frequent mutations in the spike (S) protein of PEDV, particularly in emerging variants, have substantially compromised commercial vaccine efficacy.
Yang-Yang Li   +8 more
wiley   +1 more source

Porcine Deltacoronavirus Engages the Transmissible Gastroenteritis Virus Functional Receptor Porcine Aminopeptidase N for Infectious Cellular Entry

open access: yes, 2018
Identification of cellular receptors used by coronavirus (CoV) entry into the host cells is critical to an understanding of pathogenesis and to development of intervention strategies.
Bin Wang   +11 more
core   +1 more source

Identification of a Novel Linear B-Cell Epitope on the Nucleocapsid Protein of Porcine Deltacoronavirus

open access: yes, 2020
Porcine deltacoronavirus (PDCoV), first identified in 2012, is a swine enteropathogen now found in many countries. The nucleocapsid (N) protein, a core component of PDCoV, is essential for virus replication and is a significant candidate in the ...
Xintian Wen   +11 more
core   +1 more source

Ten Years Later: Molecular Detection and Circulation of Enteric Viruses in Italian Pig Herds

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Enteric viral infections remain a major challenge for the swine industry, particularly in young animals, and represent a potential source of zoonotic risk. Ten years after a previous survey conducted in Italy, we performed a cross‐sectional study investigating mostly the same viruses to evaluate the persistence and circulation of different enteric ...
Ilaria Di Bartolo   +8 more
wiley   +1 more source

Identification of a Monoclonal Antibody against Porcine Deltacoronavirus Membrane Protein

open access: yes, 2023
Porcine deltacoronavirus (PDCoV) is an emerging virus that poses a significant threat to the global swine industry. Its membrane (M) protein is crucial for virion assembly and virus–host interactions. We selected the hydrophilic region of M protein
Zhenhai Chen   +4 more
core   +1 more source

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